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Zheng Zhou
Zheng Zhou
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Year
LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake
Z Zhou, J Zhen, NK Karpowich, RM Goetz, CJ Law, MEA Reith, DN Wang
Science 317 (5843), 1390-1393, 2007
3962007
Antidepressant specificity of serotonin transporter suggested by three LeuT–SSRI structures
Z Zhou, J Zhen, NK Karpowich, CJ Law, MEA Reith, DN Wang
Nature structural & molecular biology 16 (6), 652-657, 2009
2842009
Structure-Based Design and Synthesis of Potent Cyclic Peptides Inhibiting the YAP–TEAD Protein–Protein Interaction
Z Zhang, Z Lin, Z Zhou, HC Shen, SF Yan, AV Mayweg, Z Xu, N Qin, ...
ACS medicinal chemistry letters 5 (9), 993-998, 2014
1512014
Targeting Hippo pathway by specific interruption of YAP-TEAD interaction using cyclic YAP-like peptides
Z Zhou, T Hu, Z Xu, Z Lin, Z Zhang, T Feng, L Zhu, Y Rong, H Shen, ...
The FASEB Journal 29 (2), 724-732, 2015
1482015
Heteroaryldihydropyrimidine (HAP) and sulfamoylbenzamide (SBA) inhibit hepatitis B virus replication by different molecular mechanisms
Z Zhou, T Hu, X Zhou, S Wildum, F Garcia-Alcalde, Z Xu, D Wu, Y Mao, ...
Scientific reports 7 (1), 1-12, 2017
1322017
Design and synthesis of orally bioavailable 4-methyl heteroaryldihydropyrimidine based hepatitis B virus (HBV) capsid inhibitors
Z Qiu, X Lin, M Zhou, Y Liu, W Zhu, W Chen, W Zhang, L Guo, H Liu, G Wu, ...
Journal of medicinal chemistry 59 (16), 7651-7666, 2016
962016
Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling
JK Holden, JJ Crawford, CL Noland, S Schmidt, JR Zbieg, JA Lacap, ...
Cell Reports 31 (12), 107809, 2020
892020
Dipolar coupling between nitroxide spin labels: the development and application of a tether-in-a-cone model
EJ Hustedt, RA Stein, L Sethaphong, S Brandon, Z Zhou, SC DeSensi
Biophysical journal 90 (1), 340-356, 2006
782006
Solution structure of the cytoplasmic domain of erythrocyte membrane band 3 determined by site-directed spin labeling
Z Zhou, SC DeSensi, RA Stein, S Brandon, M Dixit, EJ McArdle, ...
Biochemistry 44 (46), 15115-15128, 2005
772005
Discovery of fluoromethylketone-based peptidomimetics as covalent ATG4B (autophagin-1) inhibitors
Z Qiu, B Kuhn, J Aebi, X Lin, H Ding, Z Zhou, Z Xu, D Xu, L Han, C Liu, ...
ACS medicinal chemistry letters 7 (8), 802-806, 2016
602016
Discovery and pre-clinical characterization of third-generation 4-H heteroaryldihydropyrimidine (HAP) analogues as hepatitis B virus (HBV) capsid inhibitors
Z Qiu, X Lin, W Zhang, M Zhou, L Guo, B Kocer, G Wu, Z Zhang, H Liu, ...
Journal of medicinal chemistry 60 (8), 3352-3371, 2017
522017
Targeting cadherin-17 inactivates Ras/Raf/MEK/ERK signaling and inhibits cell proliferation in gastric cancer
Z Lin, C Zhang, M Zhang, D Xu, Y Fang, Z Zhou, X Chen, N Qin, X Zhang
PLoS One 9 (1), e85296, 2014
522014
Discovery of Pyrido[2,3-b]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV
Y Hu, H Shi, M Zhou, Q Ren, W Zhu, W Zhang, Z Zhang, C Zhou, Y Liu, ...
Journal of Medicinal Chemistry 63 (17), 9623-9649, 2020
382020
Direct Inhibition of Hepatitis B e Antigen by Core Protein Allosteric Modulator
Z Yan, D Wu, H Hu, J Zeng, X Yu, Z Xu, Z Zhou, X Zhou, G Yang, ...
Hepatology 70 (1), 11-24, 2019
352019
Identification of new ATG4B inhibitors based on a novel high-throughput screening platform
D Xu, Z Xu, L Han, C Liu, Z Zhou, Z Qiu, X Lin, G Tang, H Shen, J Aebi, ...
SLAS Discovery 22 (4), 338-347, 2017
342017
Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation
Z Chen, Z Li, X Hu, F Xie, S Kuang, B Zhan, W Gao, X Chen, S Gao, Y Li, ...
Advanced Science, 2000532, 2020
322020
Determination of structural models of the complex between the cytoplasmic domain of erythrocyte band 3 and ankyrin-R repeats 13–24
S Kim, S Brandon, Z Zhou, CE Cobb, SJ Edwards, CW Moth, CS Parry, ...
Journal of Biological Chemistry 286 (23), 20746-20757, 2011
292011
Discovery of potent and selective CDK8 inhibitors through FBDD approach
X Han, M Jiang, C Zhou, Z Zhou, Z Xu, L Wang, AV Mayweg, R Niu, ...
Bioorganic & medicinal chemistry letters 27 (18), 4488-4492, 2017
262017
Structure of the cytoplasmic domain of erythrocyte band 3 hereditary spherocytosis variant P327R: band 3 Tuscaloosa
Z Zhou, SC DeSensi, RA Stein, S Brandon, L Song, CE Cobb, EJ Hustedt, ...
Biochemistry 46 (36), 10248-10257, 2007
262007
Discovery of Linvencorvir (RG7907), a Hepatitis B Virus Core Protein Allosteric Modulator, for the Treatment of Chronic HBV Infection
W Zhang, L Guo, H Liu, G Wu, H Shi, M Zhou, Z Zhang, B Kou, T Hu, ...
Journal of Medicinal Chemistry 66 (6), 4253-4270, 2023
122023
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