| Bioinformatic analysis of a PLP-dependent enzyme superfamily suitable for biocatalytic applications F Steffen-Munsberg, C Vickers, H Kohls, H Land, H Mallin, A Nobili, ... Biotechnology advances 33 (5), 566-604, 2015 | 242 | 2015 |
| 3DM: systematic analysis of heterogeneous superfamily data to discover protein functionalities RK Kuipers, HJ Joosten, WJH Van Berkel, NGH Leferink, E Rooijen, ... Proteins: Structure, Function, and Bioinformatics 78 (9), 2101-2113, 2010 | 197 | 2010 |
| The α/β‐hydrolase fold 3DM database (ABHDB) as a tool for protein engineering R Kourist, H Jochens, S Bartsch, R Kuipers, SK Padhi, M Gall, D Böttcher, ... ChemBioChem 11 (12), 1635-1643, 2010 | 163 | 2010 |
| Oxaloacetate hydrolase, the C–C bond lyase of oxalate secreting fungi Y Han, HJ Joosten, W Niu, Z Zhao, PS Mariano, M McCalman, J Van Kan, ... Journal of Biological Chemistry 282 (13), 9581-9590, 2007 | 122 | 2007 |
| nanoDSF as screening tool for enzyme libraries and biotechnology development AO Magnusson, A Szekrenyi, HJ Joosten, J Finnigan, S Charnock, ... The FEBS journal 286 (1), 184-204, 2019 | 107 | 2019 |
| Identification of a Gatekeeper Residue That Prevents Dehydrogenases from Acting as Oxidases*♦ NGH Leferink, MW Fraaije, HJ Joosten, PJ Schaap, A Mattevi, ... Journal of Biological Chemistry 284 (7), 4392-4397, 2009 | 103 | 2009 |
| Correlated mutation analyses on super‐family alignments reveal functionally important residues RKP Kuipers, HJ Joosten, E Verwiel, S Paans, J Akerboom, ... Proteins: Structure, Function, and Bioinformatics 76 (3), 608-616, 2009 | 93 | 2009 |
| Stress-induced hyperthermia in the mouse: c-fos expression, corticosterone and temperature changes JG Veening, JA Bouwknecht, HJJ Joosten, PJ Dederen, TJJ Zethof, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 28 (4), 699-707, 2004 | 70 | 2004 |
| Increasing the thermostability of sucrose phosphorylase by a combination of sequence-and structure-based mutagenesis A Cerdobbel, K De Winter, D Aerts, R Kuipers, HJ Joosten, W Soetaert, ... Protein Engineering, Design & Selection 24 (11), 829-834, 2011 | 67 | 2011 |
| Switch in cofactor specificity of a baeyer–villiger monooxygenase A Beier, S Bordewick, M Genz, S Schmidt, T Van Den Bergh, C Peters, ... ChemBioChem 17 (24), 2312-2315, 2016 | 60 | 2016 |
| Two subtle amino acid changes in a transaminase substantially enhance or invert enantiopreference in cascade syntheses L Skalden, C Peters, J Dickerhoff, A Nobili, HJ Joosten, K Weisz, M Höhne, ... ChemBioChem 16 (7), 1041-1045, 2015 | 60 | 2015 |
| Engineering the Amine Transaminase from Vibrio fluvialis towards Branched‐Chain Substrates M Genz, O Melse, S Schmidt, C Vickers, M Dörr, T Van Den Bergh, ... ChemCatChem 8 (20), 3199-3202, 2016 | 57 | 2016 |
| A structural classification of carbohydrate epimerases: from mechanistic insights to practical applications S Van Overtveldt, T Verhaeghe, HJ Joosten, T van den Bergh, K Beerens, ... Biotechnology Advances 33 (8), 1814-1828, 2015 | 51 | 2015 |
| Alteration of the Donor/Acceptor Spectrum of the (S)-Amine Transaminase from Vibrio fluvialis M Genz, C Vickers, T Van den Bergh, HJ Joosten, M Dörr, M Höhne, ... International journal of molecular sciences 16 (11), 26953-26963, 2015 | 45 | 2015 |
| Patterns of c-fos expression induced by fluvoxamine are different after acute vs. chronic oral administration JG Veening, LM Coolen, W Spooren, H Joosten, R Van Oorschot, J Mos, ... European neuropsychopharmacology 8 (3), 213-226, 1998 | 45 | 1998 |
| A family-based approach reveals the function of residues in the nuclear receptor ligand-binding domain S Folkertsma, P van Noort, J Van Durme, HJ Joosten, E Bettler, W Fleuren, ... Journal of Molecular Biology 341 (2), 321-335, 2004 | 43 | 2004 |
| Intravenous administration of interleukin-1β induces fos-like immunoreactivity in corticotropin-releasing hormone neurons in the paraventricular hypothalamic nucleus of the rat JG Veening, MJM van der Meer, H Joosten, ARMM Hermus, ... Journal of Chemical Neuroanatomy 6 (6), 391-397, 1993 | 43 | 1993 |
| Identification of fungal oxaloacetate hydrolyase within the isocitrate lyase/PEP mutase enzyme superfamily using a sequence marker‐based method HJ Joosten, Y Han, W Niu, J Vervoort, D Dunaway‐Mariano, PJ Schaap Proteins: Structure, Function, and Bioinformatics 70 (1), 157-166, 2008 | 41 | 2008 |
| Complete switch of reaction specificity of an aldolase by directed evolution in vitro: synthesis of generic aliphatic aldol products S Junker, R Roldan, HJ Joosten, P Clapés, WD Fessner Angewandte Chemie International Edition 57 (32), 10153-10157, 2018 | 40 | 2018 |
| Ultrastructure of the periaqueductal grey matter of the rat: an electron microscopical and horseradish peroxidase study P Buma, J Veening, T Hafmans, H Joosten, R Nieuwenhuys Journal of Comparative Neurology 319 (4), 519-535, 1992 | 35 | 1992 |
