Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v. 3.0 L Heirendt, S Arreckx, T Pfau, SN Mendoza, A Richelle, A Heinken, ... Nature protocols, 1, 2019 | 1009 | 2019 |
CANCERTOOL: a visualization and representation interface to exploit cancer datasets AR Cortazar, V Torrano, N Martín-Martín, A Caro-Maldonado, L Camacho, ... Cancer research 78 (21), 6320-6328, 2018 | 94 | 2018 |
An in-silico approach to predict and exploit synthetic lethality in cancer metabolism I Apaolaza, E San José-Eneriz, L Tobalina, E Miranda, L Garate, X Agirre, ... Nature communications 8 (1), 1-9, 2017 | 59 | 2017 |
An extended reconstruction of human gut microbiota metabolism of dietary compounds T Blasco, S Pérez-Burillo, F Balzerani, D Hinojosa-Nogueira, ... Nature Communications 12 (1), 4728, 2021 | 25 | 2021 |
gMCS: fast computation of genetic minimal cut sets in large networks I Apaolaza, LV Valcarcel, FJ Planes Bioinformatics 35 (3), 535-537, 2019 | 24 | 2019 |
Adaptation of the human gut microbiota metabolic network during the first year after birth Á Fuertes, S Pérez-Burillo, I Apaolaza, Y Vallès, MP Francino, ... Frontiers in Microbiology 10, 848, 2019 | 19 | 2019 |
In-silico gene essentiality analysis of polyamine biosynthesis reveals APRT as a potential target in cancer J Pey, E San José-Eneriz, MC Ochoa, I Apaolaza, P de Atauri, A Rubio, ... Scientific reports 7 (1), 1-10, 2017 | 15 | 2017 |
The bone marrow niche regulates redox and energy balance in MLL:: AF9 leukemia stem cells AC Viñado, IA Calvo, I Cenzano, D Olaverri, M Cocera, P San Martin-Uriz, ... Leukemia 36 (8), 1969-1979, 2022 | 9 | 2022 |
Prediction of degradation pathways of phenolic compounds in the human gut microbiota through enzyme promiscuity methods F Balzerani, D Hinojosa-Nogueira, X Cendoya, T Blasco, S Pérez-Burillo, ... npj Systems Biology and Applications 8 (1), 24, 2022 | 8 | 2022 |
A network-based approach to integrate nutrient microenvironment in the prediction of synthetic lethality in cancer metabolism I Apaolaza, E San José-Enériz, LV Valcarcel, X Agirre, F Prosper, ... PLOS Computational Biology 18 (3), e1009395, 2022 | 8 | 2022 |
Effect of Freezing on Gut Microbiota Composition and Functionality for In Vitro Fermentation Experiments S Pérez-Burillo, D Hinojosa-Nogueira, B Navajas-Porras, T Blasco, ... Nutrients 13 (7), 2207, 2021 | 8 | 2021 |
On the inconsistent treatment of gene-protein-reaction rules in context-specific metabolic models M Ponce-de-León, I Apaolaza, A Valencia, FJ Planes Bioinformatics 36 (6), 1986, 2020 | 7 | 2020 |
COBRA methods and metabolic drug targets in cancer I Apaolaza, ES José-Eneriz, X Agirre, F Prósper, FJ Planes Molecular & Cellular Oncology, e1389672, 2017 | 5 | 2017 |
Synthetic lethality in large-scale integrated metabolic and regulatory network models of human cells N Barrena, LV Valcárcel, D Olaverri-Mendizabal, I Apaolaza, FJ Planes npj Systems Biology and Applications 9 (1), 32, 2023 | 3 | 2023 |
gMCStool: automated network-based tool to search for metabolic vulnerabilities in cancer LV Valcárcel, E San José-Enériz, R Ordoñez, I Apaolaza, A Valcárcel, ... bioRxiv, 2022.11. 03.514827, 2022 | 1 | 2022 |
Computational Systems Biology Models for the Identification of Metabolic Vulnerabilities in Multiple Myeloma LVV Valcárcel, R Ordoñez, I Apaolaza, A Valcárcel, L Garate, C Meydan, ... Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019 | | 2019 |
genetic Minimal Cut Sets-gMCSs I Apaolaza, LV Valcarcel, FJ Planes | | |