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Yakov Kipnis
Yakov Kipnis
Postdoctoral Research Associate at University of Washington
Verified email at uw.edu
Title
Cited by
Cited by
Year
Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis
SD Khare, Y Kipnis, PJ Greisen, R Takeuchi, Y Ashani, M Goldsmith, ...
Nature chemical biology 8 (3), 294-300, 2012
2552012
De novo design of luciferases using deep learning
AHW Yeh, C Norn, Y Kipnis, D Tischer, SJ Pellock, D Evans, P Ma, ...
Nature 614 (7949), 774-780, 2023
1572023
Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design
S Bjelic, Y Kipnis, L Wang, Z Pianowski, S Vorobiev, M Su, ...
Journal of molecular biology 426 (1), 256-271, 2014
422014
A computational method for design of connected catalytic networks in proteins
BD Weitzner, Y Kipnis, AG Daniel, D Hilvert, D Baker
Protein Science 28 (12), 2036-2041, 2019
332019
TRINS: a method for gene modification by randomized tandem repeat insertions
Y Kipnis, E Dellus-Gur, DS Tawfik
Protein Engineering, Design & Selection 25 (9), 437-444, 2012
282012
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
Y Liu, YL Tan, X Zhang, G Bhabha, DC Ekiert, JC Genereux, Y Cho, ...
Proceedings of the National Academy of Sciences 111 (12), 4449-4454, 2014
262014
Concerted ATP-induced allosteric transitions in GroEL facilitate release of protein substrate domains in an all-or-none manner
Y Kipnis, N Papo, G Haran, A Horovitz
Proceedings of the National Academy of Sciences 104 (9), 3119-3124, 2007
262007
Comparison of designed and randomly generated catalysts for simple chemical reactions
Y Kipnis, D Baker
Protein science 21 (9), 1388-1395, 2012
242012
De Novo-Designed Enzymes as Small-Molecule-Regulated Fluorescence Imaging Tags and Fluorescent Reporters
Y Liu, X Zhang, YL Tan, G Bhabha, DC Ekiert, Y Kipnis, S Bjelic, D Baker, ...
Journal of the American Chemical Society 136 (38), 13102-13105, 2014
182014
Concerted release of substrate domains from GroEL by ATP is demonstrated with FRET
N Papo, Y Kipnis, G Haran, A Horovitz
Journal of molecular biology 380 (4), 717-725, 2008
162008
Improving protein expression, stability, and function with ProteinMPNN
KH Sumida, R Núñez-Franco, I Kalvet, SJ Pellock, BIM Wicky, LF Milles, ...
Journal of the American Chemical Society 146 (3), 2054-2061, 2024
132024
Design of an optical switch for studying conformational dynamics in individual molecules of GroEL
GA Frank, Y Kipnis, E Smolensky, SS Daube, A Horovitz, G Haran
Bioconjugate chemistry 19 (7), 1339-1341, 2008
132008
Design and optimization of enzymatic activity in a de novo β‐barrel scaffold
Y Kipnis, AO Chaib, AA Vorobieva, G Cai, G Reggiano, B Basanta, ...
Protein Science 31 (11), e4405, 2022
92022
Improving protein expression, stability, and function with ProteinMPNN
KH Sumida, R Núñez Franco, I Kalvet, SJ Pellock, BIM Wicky, LF Milles, ...
bioRxiv, 2023.10. 03.560713, 2023
52023
De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8
A Roy, L Shi, A Chang, X Dong, A Fernandez, JC Kraft, J Li, VQ Le, ...
Nature Communications 14 (1), 5660, 2023
22023
Design and optimization of enzymatic activity in a de novo฀-barrel scaffold
Y Kipnis, AO Chaib, AA Vorobieva, G Cai, G Reggiano, B Basanta, ...
2022
HARNESSING BACKBONE STRAIN TO DESIGN BETA-BARREL PROTEINS DE NOVO: FROM FIRST PRINCIPLES TO APPLICATION
A Vorobieva, J Dou, W Sheffler, B Mao, M Bick, L Doyle, J Klima, ...
PROTEIN SCIENCE 28, 115-116, 2019
2019
Blueprint for de novo protein design and engineering
AO Chaib, Y Kipnis, D Baker, D Hilvert
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
Designing de novo retroaldolase catalysts
Y Kipnis, D Baker
2019
Award Address (Nobel Laureate Signature Award for Graduate Education in Chemistry (Student) sponsored by Avantor Performance Materials). E. coli protein homeostasis network …
X Zhang, Y Cho, ET Powers, M Singh, J Yates, Y Kipnis, D Baker, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 243, 2012
2012
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