Diverse brain myeloid expression profiles reveal distinct microglial activation states and aspects of Alzheimer’s disease not evident in mouse models BA Friedman, K Srinivasan, G Ayalon, WJ Meilandt, H Lin, MA Huntley, ... Cell reports 22 (3), 832-847, 2018 | 531 | 2018 |
Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses K Srinivasan, BA Friedman, JL Larson, BE Lauffer, LD Goldstein, ... Nature communications 7 (1), 11295, 2016 | 319 | 2016 |
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration CD Pozniak, A Sengupta Ghosh, A Gogineni, JE Hanson, SH Lee, ... Journal of Experimental Medicine 210 (12), 2553-2567, 2013 | 83 | 2013 |
A common variant of IL-6R is associated with elevated IL-6 pathway activity in Alzheimer’s disease brains PCG Haddick, JL Larson, N Rathore, TR Bhangale, QT Phung, ... Journal of Alzheimer's Disease 56 (3), 1037-1054, 2017 | 47 | 2017 |
Validation of a high resolution NGS method for detecting spinal muscular atrophy carriers among phase 3 participants in the 1000 Genomes Project JL Larson, AJ Silver, D Chan, C Borroto, B Spurrier, LM Silver BMC medical genetics 16, 1-14, 2015 | 40 | 2015 |
Caspase-3 deficiency results in disrupted synaptic homeostasis and impaired attention control SC Lo, Y Wang, M Weber, JL Larson, K Scearce-Levie, M Sheng Journal of Neuroscience 35 (5), 2118-2132, 2015 | 39 | 2015 |
ReportingTools: an automated result processing and presentation toolkit for high-throughput genomic analyses MA Huntley, JL Larson, C Chaivorapol, G Becker, M Lawrence, ... Bioinformatics 29 (24), 3220-3221, 2013 | 35 | 2013 |
Targeted mutation screening panels expose systematic population bias in detection of cystic fibrosis risk RM Lim, AJ Silver, MJ Silver, C Borroto, B Spurrier, TC Petrossian, ... Genetics in medicine 18 (2), 174-179, 2016 | 31 | 2016 |
Carrier screening is a deficient strategy for determining sperm donor eligibility and reducing risk of disease in recipient children AJ Silver, JL Larson, MJ Silver, RM Lim, C Borroto, B Spurrier, A Morriss, ... Genetic testing and molecular biomarkers 20 (6), 276-284, 2016 | 29 | 2016 |
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model JL Larson, GC Yuan BMC bioinformatics 11, 1-12, 2010 | 26 | 2010 |
Diverse brain myeloid expression profiles reveal distinct microglial activation states and aspects of Alzheimer’s disease not evident in mouse models. Cell Rep 22: 832–847 BA Friedman, K Srinivasan, G Ayalon, WJ Meilandt, H Lin, MA Huntley, ... Molecular Therapy: Nucleic Acids, 2018 | 22 | 2018 |
Multilaboratory assessment of a new reference material for quality assurance of cell-free tumor DNA measurements HJ He, EV Stein, Y Konigshofer, T Forbes, FL Tomson, R Garlick, ... The Journal of Molecular Diagnostics 21 (4), 658-676, 2019 | 20 | 2019 |
Moment based gene set tests JL Larson, AB Owen BMC bioinformatics 16, 1-17, 2015 | 18 | 2015 |
Chromatin states accurately classify cell differentiation stages JL Larson, GC Yuan PloS one 7 (2), e31414, 2012 | 18 | 2012 |
A tiered hidden Markov model characterizes multi-scale chromatin states JL Larson, C Huttenhower, J Quackenbush, GC Yuan Genomics 102 (1), 1-7, 2013 | 16 | 2013 |
Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses. Nat Commun 7: 11295 K Srinivasan, BA Friedman, JL Larson, BE Lauffer, LD Goldstein, ... | 13 | 2016 |
Spine and spinal cord trauma BJ Baron, KJ McSherry, JL Larson, TM Scalea Tintinalli’s Emergency Medicine. A Comprehensive Study Guide, 1569-1582, 2011 | 12 | 2011 |
Multisite Evaluation and Validation of a Sensitive Diagnostic and Screening System for Spinal Muscular Atrophy that Reports SMN1 and SMN2 Copy Number, along with Disease … JN Milligan, JL Larson, S Filipovic-Sadic, W Laosinchai-Wolf, YW Huang, ... The Journal of Molecular Diagnostics 23 (6), 753-764, 2021 | 2 | 2021 |
Dry beriberi manifesting as acute inflammatory demyelinating polyneuropathy in a patient with decompensated alcohol-induced cirrhosis A Dhaliwal, JL Larson, BS Dhindsa, N Bhogal, FA Rochling Cureus 12 (10), 2020 | 2 | 2020 |
Chronic Inflammatory Demyelinating Polyneuropathy after Therapy with Infliximab Biosimilar J Larson, P Twohig, K Hutchins ACG Case Reports Journal 10 (2), e00993, 2023 | 1 | 2023 |