|Septic shock is correlated with asymmetrical dimethyl arginine levels, which may be influenced by a polymorphism in the dimethylarginine dimethylaminohydrolase II gene: a …|
MJ O'Dwyer, F Dempsey, V Crowley, DP Kelleher, R McManus, T Ryan
Critical Care 10 (5), R139, 2006
|Features of postoperative immune suppression are reversible with interferon gamma and independent of interleukin-6 Pathways|
ER Longbottom, HDT Torrance, HC Owen, PC Fragkou, CJ Hinds, ...
Annals of surgery 264 (2), 370-377, 2016
|The perioperative immune response|
MJ O’Dwyer, HC Owen, HDT Torrance
Current opinion in critical care 21 (4), 336-342, 2015
|The occurrence of severe sepsis and septic shock are related to distinct patterns of cytokine gene expression|
MJ O'Dwyer, AK Mankan, P Stordeur, B O'Connell, E Duggan, M White, ...
Shock 26 (4), 5-6, 2006
|Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses|
MW Lawless, AK Mankan, M White, MJ O'Dwyer, S Norris
BMC cell biology 8 (1), 30, 2007
|Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients|
HDT Torrance, K Brohi, RM Pearse, CA Mein, E Wozniak, JR Prowle, ...
Annals of surgery 261 (4), 751-759, 2015
|Systemic inflammatory response syndrome after major abdominal surgery predicted by early upregulation of TLR4 and TLR5|
R Lahiri, Y Derwa, Z Bashir, E Giles, HDT Torrance, HC Owen, ...
Annals of surgery 263 (5), 1028-1037, 2016
|The human response to infection is associated with distinct patterns of interleukin 23 and interleukin 27 expression|
MJ O’Dwyer, AK Mankan, M White, MW Lawless, P Stordeur, B O’Connell, ...
Intensive care medicine 34 (4), 683-691, 2008
|Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study|
PC Fragkou, HD Torrance, RM Pearse, GL Ackland, JR Prowle, HC Owen, ...
Critical care 18 (5), 541, 2014
|Does major surgery induce immune suppression and increase the risk of postoperative infection?|
HDT Torrance, RM Pearse, MJ O’Dwyer
Current Opinion in Anesthesiology 29 (3), 376-383, 2016
|Hospital-acquired pneumonia after lung resection surgery is associated with characteristic cytokine gene expression|
M White, I Martin-Loeches, MW Lawless, MJ O’Dwyer, DG Doherty, ...
CHEST Journal 139 (3), 626-632, 2011
|Tumor necrosis factor-α and interleukin-10 gene expression in peripheral blood mononuclear cells after cardiac surgery|
E Duggan, E Caraher, K Gately, M O'Dwyer, E McGovern, D Kelleher, ...
Critical care medicine 34 (8), 2134-2139, 2006
|Gene polymorphism and requirement for vasopressor infusion after cardiac surgery|
R Ryan, J Thornton, E Duggan, E McGovern, MJ O’Dwyer, AW Ryan, ...
The Annals of thoracic surgery 82 (3), 895-901, 2006
|Elevated MCP‐1 serum levels are associated with the H63D mutation and not the C282Y mutation in hereditary hemochromatosis|
MW Lawless, M White, AK Mankan, MJ O’Dwyer, S Norris
Tissue antigens 70 (4), 294-300, 2007
|Changes in gene expression following trauma are related to the age of transfused packed red blood cells|
HDT Torrance, ME Vivian, K Brohi, JR Prowle, RM Pearse, HC Owen, ...
Journal of Trauma and Acute Care Surgery 78 (3), 535-542, 2015
|Coagulopathy after cardiac surgery may be influenced by a functional plasminogen activator inhibitor polymorphism|
E Duggan, MJ O’dwyer, E Caraher, D Diviney, E McGovern, D Kelleher, ...
Anesthesia & Analgesia 104 (6), 1343-1347, 2007
|Transforming growth factor β-1 and interleukin-17 gene transcription in peripheral blood mononuclear cells and the human response to infection|
M White, MW Lawless, MJ O’Dwyer, R Grealy, BO Connell, P Stordeur, ...
Cytokine 50 (3), 322-327, 2010
|The detection of microbial DNA but not cultured bacteria is associated with increased mortality in patients with suspected sepsis—a prospective multi-centre European …|
MJ O’Dwyer, MH Starczewska, J Schrenzel, K Zacharowski, DJ Ecker, ...
Clinical Microbiology and Infection, 2016
|Characterization of tumour necrosis factor‐alpha genetic variants and mRNA expression in patients with severe sepsis|
MJ O'Dwyer, AK Mankan, AW Ryan, MW Lawless, P Stordeur, D Kelleher, ...
International journal of immunogenetics 35 (4‐5), 279-285, 2008
|Epigenetic regulatory pathways involving microRNAs may modulate the host immune response following major trauma|
HC Owen, HDT Torrance, TF Jones, RM Pearse, CJ Hinds, K Brohi, ...
Journal of Trauma and Acute Care Surgery 79 (5), 766-772, 2015