sheetal gandotra
sheetal gandotra
CSIR-Institute of Genomics and Integrative Biology
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In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice
S Gandotra, D Schnappinger, M Monteleone, W Hillen, S Ehrt
Nature medicine 13 (12), 1515, 2007
Perilipin deficiency and autosomal dominant partial lipodystrophy
S Gandotra, C Le Dour, W Bottomley, P Cervera, P Giral, Y Reznik, ...
New England Journal of Medicine 364 (8), 740-748, 2011
A glutamate‐alanine‐leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP
KB Hisert, M MacCoss, MU Shiloh, KH Darwin, S Singh, RA Jones, S Ehrt, ...
Molecular microbiology 56 (5), 1234-1245, 2005
Nucleotide-binding oligomerization domain protein 2-deficient mice control infection with Mycobacterium tuberculosis
S Gandotra, S Jang, PJ Murray, P Salgame, S Ehrt
Infection and immunity 75 (11), 5127-5134, 2007
Expression of many immunologically important genes in Mycobacterium tuberculosis-infected macrophages is independent of both TLR2 and TLR4 but dependent on IFN-αβ receptor and …
S Shi, A Blumenthal, CM Hickey, S Gandotra, D Levy, S Ehrt
The Journal of Immunology 175 (5), 3318-3328, 2005
Human frame shift mutations affecting the carboxyl terminus of perilipin increase lipolysis by failing to sequester the adipose triglyceride lipase (ATGL) coactivator AB …
S Gandotra, K Lim, A Girousse, V Saudek, S O'Rahilly, DB Savage
Journal of Biological Chemistry 286 (40), 34998-35006, 2011
The Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide
S Gandotra, MB Lebron, S Ehrt
PLoS pathogens 6 (8), e1001040, 2010
A network map of Interleukin-10 signaling pathway
R Verma, L Balakrishnan, K Sharma, AA Khan, J Advani, H Gowda, ...
Journal of cell communication and signaling 10 (1), 61-67, 2016
Clinical and molecular characterization of a novel PLIN1 frameshift mutation identified in patients with familial partial lipodystrophy
K Kozusko, VHM Tsang, W Bottomley, YH Cho, S Gandotra, M Mimmack, ...
Diabetes 64 (1), 299-310, 2015
The functionally conserved nucleoporins Nup124p from fission yeast and the human Nup153 mediate nuclear import and activity of the Tf1 retrotransposon and HIV-1 Vpr
P Varadarajan, S Mahalingam, P Liu, SBH Ng, S Gandotra, ...
Molecular biology of the cell 16 (4), 1823-1838, 2005
Quantitative Proteomic and Phosphoproteomic Analysis of H37Ra and H37Rv Strains of Mycobacterium tuberculosis
R Verma, SM Pinto, AH Patil, J Advani, P Subba, M Kumar, J Sharma, ...
Journal of Proteome Research 16 (4), 1632-1645, 2017
Secretory phosphatases deficient mutant of Mycobacterium tuberculosis imparts protection at the primary site of infection in guinea pigs
P Chauhan, PV Reddy, R Singh, N Jaisinghani, S Gandotra, AK Tyagi
PloS one 8 (10), e77930, 2013
Protein kinase A (PknA) of Mycobacterium tuberculosis is independently activated and is critical for growth in vitro and survival of the pathogen in the host
SN Nagarajan, S Upadhyay, Y Chawla, S Khan, S Naz, J Subramanian, ...
Journal of Biological Chemistry 290 (15), 9626-9645, 2015
Necrosis driven triglyceride synthesis primes macrophages for inflammation during Mycobacterium tuberculosis infection
N Jaisinghani, S Dawa, K Singh, A Nandy, D Menon, PD Bhandari, ...
Frontiers in Immunology 9, 1490, 2018
clpC operon regulates cell architecture and sporulation in Bacillus anthracis
LK Singh, N Dhasmana, A Sajid, P Kumar, A Bhaduri, M Bharadwaj, ...
Environmental microbiology 17 (3), 855-865, 2015
Phospholipid homeostasis, membrane tenacity and survival of Mtb in lipid rich conditions is determined by MmpL11 function
A Bothra, P Arumugam, V Panchal, D Menon, S Srivastava, D Shankaran, ...
Scientific reports 8 (1), 8317, 2018
Quantitative lipid droplet proteomics reveals Mycobacterium tuberculosis induced alterations in macrophage response to infection
D Menon, K Singh, SM Pinto, A Nandy, N Jaisinghani, R Kutum, D Dash, ...
ACS infectious diseases, 2019
The MmpS6-MmpL6 operon is an oxidative stress response system providing selective advantage to Mycobacterium tuberculosis in stress
P Arumugam, D Shankaran, A Bothra, S Gandotra, V Rao
The Journal of infectious diseases, 2018
Adipocyte model of Mycobacterium tuberculosis infection reveals differential iron availability to bacilli in the lipid rich caseous environment
A Nandy, AK Mondal, R Pandey, P Arumugam, S Dawa, N Jaisinghani, ...
Infection and immunity, IAI. 00041-18, 2018
Integrated Multi-Omic Analysis of Mycobacterium tuberculosis H37Ra Redefines Virulence Attributes
SM Pinto, R Verma, J Advani, O Chatterjee, AH Patil, S Kapoor, ...
Frontiers in microbiology 9, 2018
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