| The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3. 2 channel activity A García-Caballero, VM Gadotti, P Stemkowski, N Weiss, IA Souza, ... Neuron 83 (5), 1144-1158, 2014 | 229 | 2014 |
| A neuronal circuit for activating descending modulation of neuropathic pain J Huang, VM Gadotti, L Chen, IA Souza, S Huang, D Wang, ... Nature neuroscience 22 (10), 1659-1668, 2019 | 220 | 2019 |
| Role of prelimbic GABAergic circuits in sensory and emotional aspects of neuropathic pain Z Zhang, VM Gadotti, L Chen, IA Souza, PL Stemkowski, GW Zamponi Cell reports 12 (5), 752-759, 2015 | 214 | 2015 |
| Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission MS Guzman, X De Jaeger, S Raulic, IA Souza, AX Li, S Schmid, ... PLoS biology 9 (11), e1001194, 2011 | 115 | 2011 |
| De novo pathogenic variants in CACNA1E cause developmental and epileptic encephalopathy with contractures, macrocephaly, and dyskinesias KL Helbig, RJ Lauerer, JC Bahr, IA Souza, CT Myers, B Uysal, N Schwarz, ... The American Journal of Human Genetics 103 (5), 666-678, 2018 | 111 | 2018 |
| Analgesic effect in rodents of native and recombinant Phα1β toxin, a high-voltage-activated calcium channel blocker isolated from armed spider venom AH Souza, J Ferreira, M do Nascimento Cordeiro, LB Vieira, CJ De Castro, ... Pain 140 (1), 115-126, 2008 | 107 | 2008 |
| Amyloid‐beta oligomers increase the localization of prion protein at the cell surface FA Caetano, FH Beraldo, GNM Hajj, AL Guimaraes, S Jürgensen, ... Journal of neurochemistry 117 (3), 538-553, 2011 | 91 | 2011 |
| BK potassium channels suppress Cavα2δ subunit function to reduce inflammatory and neuropathic pain FX Zhang, VM Gadotti, IA Souza, L Chen, GW Zamponi Cell reports 22 (8), 1956-1964, 2018 | 57 | 2018 |
| TRPV1 nociceptor activity initiates USP5/T-type channel-mediated plasticity P Stemkowski, A García-Caballero, VDM Gadotti, S M'Dahoma, S Huang, ... Cell reports 17 (11), 2901-2912, 2016 | 55 | 2016 |
| Identification of interleukin-1 beta as a key mediator in the upregulation of Cav3. 2–USP5 interactions in the pain pathway PL Stemkowski, A Garcia-Caballero, VM Gadotti, S M’Dahoma, L Chen, ... Molecular pain 13, 1744806917724698, 2017 | 52 | 2017 |
| Block of T-type calcium channels by protoxins I and II C Bladen, J Hamid, IA Souza, GW Zamponi Molecular brain 7, 1-8, 2014 | 50 | 2014 |
| A novel calmodulin site in the Cav1. 2 N-terminus regulates calcium-dependent inactivation BA Simms, IA Souza, GW Zamponi Pflügers Archiv-European Journal of Physiology 466, 1793-1803, 2014 | 40 | 2014 |
| TNF-α mediated upregulation of NaV1.7 currents in rat dorsal root ganglion neurons is independent of CRMP2 SUMOylation FHP De Macedo, RD Aires, EG Fonseca, RCM Ferreira, DPD Machado, ... Molecular brain 12, 1-14, 2019 | 30 | 2019 |
| Two heterozygous Cav3.2 channel mutations in a pediatric chronic pain patient: recording condition-dependent biophysical effects IA Souza, MA Gandini, MM Wan, GW Zamponi Pflugers Arch, 635-42, 2016 | 26 | 2016 |
| CaV3. 2 calcium channels contribute to trigeminal neuralgia E Gambeta, MA Gandini, IA Souza, GW Zamponi Pain 163 (12), 2315-2325, 2022 | 24 | 2022 |
| The Cav1. 2 N terminus contains a CaM kinase site that modulates channel trafficking and function BA Simms, IA Souza, R Rehak, GW Zamponi Pflügers Archiv-European Journal of Physiology 467, 677-686, 2015 | 23 | 2015 |
| Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP−/− Mice J Fan, PL Stemkowski, MA Gandini, SA Black, Z Zhang, IA Souza, L Chen, ... Frontiers in cellular neuroscience 10, 74, 2016 | 19 | 2016 |
| A rare CACNA1H variant associated with amyotrophic lateral sclerosis causes complete loss of Cav3.2 T-type channel activity RN Stringer, B Jurkovicova-Tarabova, S Huang, O Haji-Ghassemi, ... Molecular Brain 13, 1-11, 2020 | 18 | 2020 |
| Differential regulation of Cav3.2 and Cav2.2 calcium channels by CB1 receptors and cannabidiol EK Harding, IA Souza, MA Gandini, VM Gadotti, MY Ali, S Huang, ... British Journal of Pharmacology 180 (12), 1616-1633, 2023 | 17 | 2023 |
| T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B A Garcia-Caballero, FX Zhang, V Hodgkinson, J Huang, L Chen, IA Souza, ... Molecular brain 11, 1-10, 2018 | 16 | 2018 |
