Greg Findlay
Greg Findlay
Principal Investigator, MRC-PPU, University of Dundee
Email verificata su - Home page
Citata da
Citata da
The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins
LS Harrington, GM Findlay, A Gray, T Tolkacheva, S Wigfield, H Rebholz, ...
The Journal of cell biology 166 (2), 213-223, 2004
Restraining PI3K: mTOR signalling goes back to the membrane
LS Harrington, GM Findlay, RF Lamb
Trends in biochemical sciences 30 (1), 35-42, 2005
A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling
GM Findlay, L Yan, J Procter, V Mieulet, RF Lamb
Biochemical Journal 403 (1), 13-20, 2007
PP2AT61ɛ is an inhibitor of MAP4K3 in nutrient signaling to mTOR
L Yan, V Mieulet, D Burgess, GM Findlay, K Sully, J Procter, J Goris, ...
Molecular cell 37 (5), 633-642, 2010
A quantitative liposome microarray to systematically characterize protein-lipid interactions
AE Saliba, I Vonkova, S Ceschia, GM Findlay, K Maeda, C Tischer, ...
nature methods 11 (1), 47-50, 2014
Hyperactivation of mammalian target of rapamycin (mTOR) signaling by a gain-of-function mutant of the Rheb GTPase
L Yan, GM Findlay, R Jones, J Procter, Y Cao, RF Lamb
Journal of Biological Chemistry 281 (29), 19793-19797, 2006
Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate
GM Findlay, MJ Smith, F Lanner, MS Hsiung, GD Gish, E Petsalaki, ...
Cell 152 (5), 1008-1020, 2013
TSC1-2 tumour suppressor and regulation of mTOR signalling: linking cell growth and proliferation?
GM Findlay, LS Harrington, RF Lamb
Current opinion in genetics & development 15 (1), 69-76, 2005
Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation
N Yasui, GM Findlay, GD Gish, MS Hsiung, J Huang, M Tucholska, ...
Molecular cell 54 (6), 1034-1041, 2014
Erk5 is a key regulator of naive-primed transition and embryonic stem cell identity
CAC Williams, R Fernandez-Alonso, J Wang, R Toth, NS Gray, ...
Cell reports 16 (7), 1820-1828, 2016
How is SOS activated? Let us count the ways
GM Findlay, T Pawson
Nature structural & molecular biology 15 (6), 538-540, 2008
Protein kinases in pluripotency—beyond the usual suspects
R Fernandez-Alonso, F Bustos, CAC Williams, GM Findlay
Journal of molecular biology 429 (10), 1504-1520, 2017
Brd4‐Brd2 isoform switching coordinates pluripotent exit and Smad2‐dependent lineage specification
R Fernandez‐Alonso, L Davidson, J Hukelmann, M Zengerle, AR Prescott, ...
EMBO reports 18 (7), 1108-1122, 2017
RNF12 X-linked intellectual disability mutations disrupt E3 ligase activity and neural differentiation
F Bustos, A Segarra-Fas, VK Chaugule, L Brandenburg, E Branigan, ...
Cell reports 23 (6), 1599-1611, 2018
A simple method to identify kinases that regulate embryonic stem cell pluripotency by high-throughput inhibitor screening
CAC Williams, NS Gray, GM Findlay
JoVE (Journal of Visualized Experiments), e55515, 2017
Phosphoproteomics identifies a bimodal EPHA2 receptor switch that promotes embryonic stem cell differentiation
R Fernandez-Alonso, F Bustos, M Budzyk, P Kumar, AO Helbig, ...
Nature Communications 11 (1), 1-13, 2020
Profiling embryonic stem cell differentiation by MALDI TOF mass spectrometry: development of a reproducible and robust sample preparation workflow
RE Heap, A Segarra-Fas, AP Blain, GM Findlay, M Trost
Analyst 144 (21), 6371-6381, 2019
Profiling embryonic stem cell differentiation by MALDI-MS: development of a reproducible and robust sample preparation workflow
RE Heap, AS Fas, G Findlay, M Trost
bioRxiv, 536664, 2019
Molecular Mechanisms of Stem Cell Pluripotency and Cell Fate Specification
GM Findlay, L David, TA Beyer
Journal of molecular biology 429 (10), 1439-1440, 2017
Online Commentary
C Hindley, A Philpott, M Sauter, B Moffatt, MC Saechao, R Hell, M Wirtz
BIOCHEMICAL JOURNAL 451 (part 2), 2013
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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