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Florencia Rago
Florencia Rago
Novartis Institutes for Biomedical Research
Email verificata su novartis.com
Titolo
Citata da
Citata da
Anno
CENP‐T provides a structural platform for outer kinetochore assembly
T Nishino, F Rago, T Hori, K Tomii, IM Cheeseman, T Fukagawa
The EMBO journal 32 (3), 424-436, 2013
2312013
Distinct organization and regulation of the outer kinetochore KMN network downstream of CENP-C and CENP-T
F Rago, KE Gascoigne, IM Cheeseman
Current Biology 25 (5), 671-677, 2015
1502015
Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program
P Thiru, DM Kern, KL McKinley, JK Monda, F Rago, KC Su, T Tsinman, ...
Molecular biology of the cell 25 (13), 1983-1994, 2014
592014
The functions and consequences of force at kinetochores
F Rago, IM Cheeseman
Journal of Cell Biology 200 (5), 557-565, 2013
572013
Degron mediated BRM/SMARCA2 depletion uncovers novel combination partners for treatment of BRG1/SMARCA4-mutant cancers
F Rago, MT DiMare, GN Elliott, DA Ruddy, S Sovath, G Kerr, CB Hyo-eun, ...
Biochemical and biophysical research communications 508 (1), 109-116, 2019
292019
Exquisite sensitivity to dual BRG1/BRM ATPase inhibitors reveals broad SWI/SNF dependencies in acute myeloid leukemia
F Rago, LU Rodrigues, M Bonney, K Sprouffske, E Kurth, GN Elliott, ...
Molecular cancer research 20 (3), 361-372, 2022
242022
Enzyme substrate specificity conferred by distinct conformational pathways
F Rago, D Saltzberg, KN Allen, DR Tolan
Journal of the American Chemical Society 137 (43), 13876-13886, 2015
212015
The discovery of SWI/SNF chromatin remodeling activity as a novel and targetable dependency in uveal melanoma
F Rago, GN Elliott, A Li, K Sprouffske, G Kerr, A Desplat, D Abramowski, ...
Molecular cancer therapeutics 19 (10), 2186-2195, 2020
192020
In-Depth Characterization and Validation in BRG1-Mutant Lung Cancers Define Novel Catalytic Inhibitors of SWI/SNF Chromatin Remodeling
Z Jagani, G Chenail, K Xiang, G Bushold, HEC Bhang, A Li, GN Elliott, ...
Biorxiv, 812628, 2019
102019
Identification of a novel dependence on the SWI/SNF chromatin remodeling complex in uveal melanoma
F Rago, X Xiang, A Desplat, E Niemezyk, D Ruddy, G Kerr, EM Robles, ...
Cancer Research 78 (13_Supplement), 361-361, 2018
2018
Controlled and endogenous depletion of a synthetic lethal target in human cancer cell lines via SMASh degron engineering
F Rago, MT Dimare, G Bushold, A Kapoor, HC Bhang, Z Jagani
Cancer Research 77 (13_Supplement), 1025-1025, 2017
2017
Organization and regulation of outer kinetochore assembly
F Rago
Massachusetts Institute of Technology, 2015
2015
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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