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Prathap Kumar S. Mahalingaiah
Prathap Kumar S. Mahalingaiah
Email verificata su abbvie.com
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Chronic oxidative stress increases growth and tumorigenic potential of MCF-7 breast cancer cells
PKS Mahalingaiah, KP Singh
PloS one 9 (1), e87371, 2014
1462014
Potential mechanisms of target-independent uptake and toxicity of antibody-drug conjugates
PK Mahalingaiah, R Ciurlionis, KR Durbin, RL Yeager, BK Philip, B Bawa, ...
Pharmacology & Therapeutics 200, 110-125, 2019
1212019
Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology
L Ewart, A Apostolou, SA Briggs, CV Carman, JT Chaff, AR Heng, ...
Communications medicine 2 (1), 154, 2022
892022
Oxidative stress-induced epigenetic changes associated with malignant transformation of human kidney epithelial cells
PKS Mahalingaiah, L Ponnusamy, KP Singh
Oncotarget 8 (7), 11127, 2017
652017
Potentiation of growth inhibition and epigenetic modulation by combination of green tea polyphenol and 5-aza-2′-deoxycytidine in human breast cancer cells
T Tyagi, JN Treas, PKS Mahalingaiah, KP Singh
Breast cancer research and treatment 149, 655-668, 2015
542015
Chronic oxidative stress leads to malignant transformation along with acquisition of stem cell characteristics, and epithelial to mesenchymal transition in human renal …
PKS Mahalingaiah, L Ponnusamy, KP Singh
Journal of cellular physiology 230 (8), 1916-1928, 2015
502015
Chronic oxidative stress causes estrogen-independent aggressive phenotype, and epigenetic inactivation of estrogen receptor alpha in MCF-7 breast cancer cells
PKS Mahalingaiah, L Ponnusamy, KP Singh
Breast Cancer Research and Treatment 153, 41-56, 2015
382015
Reversal of epigenetic aberrations associated with the acquisition of doxorubicin resistance restores drug sensitivity in breast cancer cells
L Ponnusamy, PKS Mahalingaiah, YW Chang, KP Singh
European Journal of Pharmaceutical Sciences 123, 56-69, 2018
332018
Application of microphysiological systems in biopharmaceutical research and development
NC Peterson, PK Mahalingaiah, A Fullerton, M Di Piazza
Lab on a Chip 20 (4), 697-708, 2020
292020
Epigenetic reprogramming and potential application of epigenetic-modifying drugs in acquired chemotherapeutic resistance
L Ponnusamy, PKS Mahalingaiah, KP Singh
Advances in clinical chemistry 94, 219-259, 2020
252020
Treatment schedule and estrogen receptor-status influence acquisition of doxorubicin resistance in breast cancer cells
L Ponnusamy, PKS Mahalingaiah, KP Singh
European Journal of Pharmaceutical Sciences 104, 424-433, 2017
242017
Chronic oxidative stress increases resistance to doxorubicin-induced cytotoxicity in renal carcinoma cells potentially through epigenetic mechanism
L Ponnusamy, PKS Mahalingaiah, KP Singh
Molecular Pharmacology 89 (1), 27-41, 2016
222016
Role of cellular reprogramming and epigenetic dysregulation in acquired chemoresistance in breast cancer
L Ponnusamy, PKS Mahalingaiah, YW Chang, KP Singh
Cancer Drug Resistance 2 (2), 297, 2019
212019
Mitochondrial dysfunction caused by drugs and environmental toxicants
Y Will, JA Dykens
John Wiley & Sons, 2018
212018
Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications
L Ewart, A Apostolou, SA Briggs, CV Carman, JT Chaff, AR Heng, ...
Biorxiv, 2021.12. 14.472674, 2021
182021
An In Vitro Model of Hematotoxicity: Differentiation of Bone Marrow–Derived Stem/Progenitor Cells into Hematopoietic Lineages and Evaluation of Lineage‐Specific Hematotoxicity
PK Mahalingaiah, T Palenski, TR Van Vleet
Current protocols in toxicology 76 (1), e45, 2018
172018
In-vivo anti-inflammatory effect of aqueous and ethanolic extract of Sida rhombifolia l. Root
P Logeswari, V Dineshkumar, SMP Kumar, PTA Usha
International Journal of Pharmaceutical Sciences and Research 4 (1), 316, 2013
172013
Nonclinical studies that support viral vector-delivered gene therapies: an EFPIA gene therapy working group perspective
MW Bolt, LO Whiteley, JL Lynch, B Lauritzen, ARF de Henestrosa, ...
Molecular Therapy-Methods & Clinical Development 19, 89-98, 2020
112020
Proximate Analysis of Sida Rhombifolia L Root and Its Effect on Cadmium Chloride Induced Alterations In Body Weight Of Wistar Rats.
P Logeswari, V Dineshkumar, PTA Usha, SM Prathap Kumar
IJPBS International Journal of Pharmacy and Biological Sciences 2 (3), 303-309, 2012
62012
Towards in vitro models for reducing or replacing the use of animals in drug testing
DM Stresser, AK Kopec, P Hewitt, RN Hardwick, TR Van Vleet, ...
Nature Biomedical Engineering, 1-6, 2023
52023
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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