Chronic oxidative stress increases growth and tumorigenic potential of MCF-7 breast cancer cells PKS Mahalingaiah, KP Singh PloS one 9 (1), e87371, 2014 | 146 | 2014 |
Potential mechanisms of target-independent uptake and toxicity of antibody-drug conjugates PK Mahalingaiah, R Ciurlionis, KR Durbin, RL Yeager, BK Philip, B Bawa, ... Pharmacology & Therapeutics 200, 110-125, 2019 | 121 | 2019 |
Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology L Ewart, A Apostolou, SA Briggs, CV Carman, JT Chaff, AR Heng, ... Communications medicine 2 (1), 154, 2022 | 89 | 2022 |
Oxidative stress-induced epigenetic changes associated with malignant transformation of human kidney epithelial cells PKS Mahalingaiah, L Ponnusamy, KP Singh Oncotarget 8 (7), 11127, 2017 | 65 | 2017 |
Potentiation of growth inhibition and epigenetic modulation by combination of green tea polyphenol and 5-aza-2′-deoxycytidine in human breast cancer cells T Tyagi, JN Treas, PKS Mahalingaiah, KP Singh Breast cancer research and treatment 149, 655-668, 2015 | 54 | 2015 |
Chronic oxidative stress leads to malignant transformation along with acquisition of stem cell characteristics, and epithelial to mesenchymal transition in human renal … PKS Mahalingaiah, L Ponnusamy, KP Singh Journal of cellular physiology 230 (8), 1916-1928, 2015 | 50 | 2015 |
Chronic oxidative stress causes estrogen-independent aggressive phenotype, and epigenetic inactivation of estrogen receptor alpha in MCF-7 breast cancer cells PKS Mahalingaiah, L Ponnusamy, KP Singh Breast Cancer Research and Treatment 153, 41-56, 2015 | 38 | 2015 |
Reversal of epigenetic aberrations associated with the acquisition of doxorubicin resistance restores drug sensitivity in breast cancer cells L Ponnusamy, PKS Mahalingaiah, YW Chang, KP Singh European Journal of Pharmaceutical Sciences 123, 56-69, 2018 | 33 | 2018 |
Application of microphysiological systems in biopharmaceutical research and development NC Peterson, PK Mahalingaiah, A Fullerton, M Di Piazza Lab on a Chip 20 (4), 697-708, 2020 | 29 | 2020 |
Epigenetic reprogramming and potential application of epigenetic-modifying drugs in acquired chemotherapeutic resistance L Ponnusamy, PKS Mahalingaiah, KP Singh Advances in clinical chemistry 94, 219-259, 2020 | 25 | 2020 |
Treatment schedule and estrogen receptor-status influence acquisition of doxorubicin resistance in breast cancer cells L Ponnusamy, PKS Mahalingaiah, KP Singh European Journal of Pharmaceutical Sciences 104, 424-433, 2017 | 24 | 2017 |
Chronic oxidative stress increases resistance to doxorubicin-induced cytotoxicity in renal carcinoma cells potentially through epigenetic mechanism L Ponnusamy, PKS Mahalingaiah, KP Singh Molecular Pharmacology 89 (1), 27-41, 2016 | 22 | 2016 |
Role of cellular reprogramming and epigenetic dysregulation in acquired chemoresistance in breast cancer L Ponnusamy, PKS Mahalingaiah, YW Chang, KP Singh Cancer Drug Resistance 2 (2), 297, 2019 | 21 | 2019 |
Mitochondrial dysfunction caused by drugs and environmental toxicants Y Will, JA Dykens John Wiley & Sons, 2018 | 21 | 2018 |
Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications L Ewart, A Apostolou, SA Briggs, CV Carman, JT Chaff, AR Heng, ... Biorxiv, 2021.12. 14.472674, 2021 | 18 | 2021 |
An In Vitro Model of Hematotoxicity: Differentiation of Bone Marrow–Derived Stem/Progenitor Cells into Hematopoietic Lineages and Evaluation of Lineage‐Specific Hematotoxicity PK Mahalingaiah, T Palenski, TR Van Vleet Current protocols in toxicology 76 (1), e45, 2018 | 17 | 2018 |
In-vivo anti-inflammatory effect of aqueous and ethanolic extract of Sida rhombifolia l. Root P Logeswari, V Dineshkumar, SMP Kumar, PTA Usha International Journal of Pharmaceutical Sciences and Research 4 (1), 316, 2013 | 17 | 2013 |
Nonclinical studies that support viral vector-delivered gene therapies: an EFPIA gene therapy working group perspective MW Bolt, LO Whiteley, JL Lynch, B Lauritzen, ARF de Henestrosa, ... Molecular Therapy-Methods & Clinical Development 19, 89-98, 2020 | 11 | 2020 |
Proximate Analysis of Sida Rhombifolia L Root and Its Effect on Cadmium Chloride Induced Alterations In Body Weight Of Wistar Rats. P Logeswari, V Dineshkumar, PTA Usha, SM Prathap Kumar IJPBS International Journal of Pharmacy and Biological Sciences 2 (3), 303-309, 2012 | 6 | 2012 |
Towards in vitro models for reducing or replacing the use of animals in drug testing DM Stresser, AK Kopec, P Hewitt, RN Hardwick, TR Van Vleet, ... Nature Biomedical Engineering, 1-6, 2023 | 5 | 2023 |