| HECT E3 ubiquitin ligases–emerging insights into their biological roles and disease relevance Y Wang, D Argiles-Castillo, EI Kane, A Zhou, DE Spratt Journal of cell science 133 (7), jcs228072, 2020 | 111 | 2020 |
| Structural insights into ankyrin repeat-containing proteins and their influence in ubiquitylation EI Kane, DE Spratt International journal of molecular sciences 22 (2), 609, 2021 | 19 | 2021 |
| Small-molecule Gankyrin inhibition as a therapeutic strategy for breast and lung cancer D Kanabar, M Goyal, EI Kane, T Chavan, A Kabir, X Wang, S Shukla, ... Journal of medicinal chemistry 65 (13), 8975-8997, 2022 | 6 | 2022 |
| Intersection of redox chemistry and ubiquitylation: post-translational modifications required for maintaining cellular homeostasis and neuroprotection EI Kane, KL Waters, DE Spratt Cells 10 (8), 2121, 2021 | 4 | 2021 |
| New discoveries on the roles of “other” HECT E3 ubiquitin ligases in disease development EI Kane, DE Spratt Ubiquitin-Proteasome Pathway, 2020 | 4 | 2020 |
| Redefining the catalytic HECT domain boundaries for the HECT E3 ubiquitin ligase family EI Kane, SA Beasley, JM Schafer, JE Bohl, YS Lee, KJ Rich, EF Bosia, ... Bioscience reports 42 (10), BSR20221036, 2022 | 2 | 2022 |
| Synthesis and evaluation of 2, 5-substituted pyrimidines as small-molecule gankyrin binders D Kanabar, EI Kane, T Chavan, TM Laflamme, E Suarez, M Goyal, ... Future Medicinal Chemistry 16 (3), 239-251, 2024 | | 2024 |
| Targeting the Oncoprotein Gankyrin with Small Molecules to Alter its 3D Global Fold M Riyazi, T Laflamme, E Kane, D Kanabar, T Chavan, A Muth, DE Spratt PROTEIN SCIENCE 32 (12), 2023 | | 2023 |
| Hereditary Spastic Paraplegia Linked Mutations in Rac1 Cause Structural Changes that Disrupt ROS Accumulation L Mazur, E Kane, DE Spratt PROTEIN SCIENCE 32 (12), 2023 | | 2023 |
| Specificity studies of small molecule inhibitors targeting the ankyrin-repeat oncoprotein gankyrin T Laflamme, E Kane, DE Spratt, A Muth, D Kanabar, T Chavan PROTEIN SCIENCE 32 (12), 2023 | | 2023 |
| PARALLEL LOSS OF SEX IN FIELD POPULATIONS OF A BROWN ALGA SHEDS LIGHT ON THE MECHANISMS UNDERLYING THE EMERGENCE OF ASEXUALITY M Hoshino, G Cossard, FB Haas, E Kane, K Kogame, T Jomori, ... bioRxiv, 2023.09. 10.557039, 2023 | | 2023 |
| Biochemical and Biophysical Characterization of Small Molecule Inhibition of Gankyrin as a Therapeutic Strategy for Cancers E Kane, D Kanabar, A Kabir, T Laflamme, A Muth, D Spratt PROTEIN SCIENCE 32, 2023 | | 2023 |
| Extending the Catalytic HECT Domain Boundaries for the HECT E3 Ubiquitin Ligase HACE1 Increases Solubility and Enzymatic Activity EI Kane, K Rich, S Beasley, DE Spratt The FASEB Journal 36, 2022 | | 2022 |
| Ankyrin Repeats in Cancer and Neurodevelopment: Multifunctionality of E3 Ligase-Substrate Interactions in HECT-Dependent Ubiquitylation EI Kane Clark University, 2022 | | 2022 |
