Melchiorre Cervello
Melchiorre Cervello
Institute for Biomedical Research and Innovation (IRIB) - CNR - Palermo - Italy
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Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging
LS Steelman, WH Chappell, SL Abrams, CR Kempf, J Long, P Laidler, ...
Aging (Albany NY) 3 (3), 192, 2011
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health
WH Chappell, LS Steelman, JM Long, RC Kempf, SL Abrams, RA Franklin, ...
Oncotarget 2 (3), 135, 2011
Epidemiology, risk factors, and natural history of hepatocellular carcinoma
G Montalto, M Cervello, L Giannitrapani, F Dantona, A Terranova, ...
Annals of the New York Academy of Sciences 963 (1), 13-20, 2002
Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB …
M Notarbartolo, P Poma, D Perri, L Dusonchet, M Cervello, ...
Cancer letters 224 (1), 53-65, 2005
GSK-3 as potential target for therapeutic intervention in cancer
JA McCubrey, LS Steelman, FE Bertrand, NM Davis, M Sokolosky, ...
Oncotarget 5 (10), 2881, 2014
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance
JA McCubrey, LS Steelman, WH Chappell, SL Abrams, RA Franklin, ...
Oncotarget 3 (10), 1068, 2012
Sex hormones and risk of liver tumor
L Giannitrapani, M Soresi, E La Spada, M Cervello, N D'alessandro, ...
Annals of the New York Academy of Sciences 1089 (1), 228-236, 2006
Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response
JA McCubrey, LS Steelman, WH Chappell, SL Abrams, G Montalto, ...
Oncotarget 3 (9), 954, 2012
Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention
NM Davis, M Sokolosky, K Stadelman, SL Abrams, M Libra, S Candido, ...
Oncotarget 5 (13), 4603, 2014
Targeting the leukemic stem cell: the Holy Grail of leukemia therapy
N Misaghian, G Ligresti, LS Steelman, FE Bertrand, J Bäsecke, M Libra, ...
Leukemia 23 (1), 25-42, 2009
Targeted therapy for hepatocellular carcinoma: novel agents on the horizon
M Cervello, JA McCubrey, A Cusimano, N Lampiasi, A Azzolina, ...
Oncotarget 3 (3), 236, 2012
The tumor microenvironment in hepatocellular carcinoma
GC Leonardi, S Candido, M Cervello, D Nicolosi, F Raiti, S Travali, ...
International journal of oncology 40 (6), 1733-1747, 2012
Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention
JA McCubrey, LS Steelman, FE Bertrand, NM Davis, SL Abrams, ...
Leukemia 28 (1), 15-33, 2014
Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways
JA McCubrey, LS Steelman, CR Kempf, WH Chappell, SL Abrams, ...
Journal of cellular physiology 226 (11), 2762-2781, 2011
Akt as a therapeutic target in cancer
LS Steelman, KM Stadelman, WH Chappell, S Horn, J Bäsecke, ...
Expert opinion on therapeutic targets 12 (9), 1139-1165, 2008
Cyclooxygenases in hepatocellular carcinoma
M Cervello, G Montalto
World journal of gastroenterology 12 (32), 5113, 2006
Resistance to diverse apoptotic triggers in multidrug resistant HL60 cells and its possible relationship to the expression of P-glycoprotein, Fas and of the novel anti …
M Notarbartolo, M Cervello, L Dusonchet, A Cusimano, N D'Alessandro
Cancer letters 180 (1), 91-101, 2002
Transcriptional regulation of miR-224 upregulated in human HCCs by NFκB inflammatory pathways
C Scisciani, S Vossio, F Guerrieri, V Schinzari, R De Iaco, PDO de Meo, ...
Journal of hepatology 56 (4), 855-861, 2012
Interleukin-6 and its soluble receptor in patients with liver cirrhosis and hepatocellular carcinoma
M Soresi, L Giannitrapani, F D’Antona, AM Florena, E La Spada, ...
World journal of gastroenterology: WJG 12 (16), 2563, 2006
Targeting the Raf/MEK/ERK pathway with small-molecule inhibitors.
JA McCubrey, M Milella, A Tafuri, AM Martelli, P Lunghi, A Bonati, ...
Current opinion in investigational drugs (London, England: 2000) 9 (6), 614-630, 2008
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