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Ryan M. Carr
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Clinical, molecular, and prognostic correlates of number, type, and functional localization of TET2 mutations in chronic myelomonocytic leukemia (CMML)—a study …
G Coltro, AA Mangaonkar, TL Lasho, CM Finke, P Pophali, R Carr, ...
Leukemia 34 (5), 1407-1421, 2020
802020
Pancreatic cancer microenvironment, to target or not to target?
RM Carr, ME Fernandez‐Zapico
EMBO molecular medicine 8 (2), 80-82, 2016
742016
Suboptimal response rates to hypomethylating agent therapy in chronic myelomonocytic leukemia; a single institutional study of 121 patients
T Coston, P Pophali, R Vallapureddy, TL Lasho, CM Finke, RP Ketterling, ...
American journal of hematology 94 (7), 767-779, 2019
622019
ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL
S Pietrobono, G Anichini, C Sala, F Manetti, LL Almada, S Pepe, RM Carr, ...
Nature communications 11 (1), 5865, 2020
572020
Akt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association …
P Li, S Jayarama, L Ganesh, D Mordi, R Carr, P Kanteti, N Hay, ...
Journal of biological chemistry 285 (29), 22713-22722, 2010
522010
RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis
RM Carr, D Vorobyev, T Lasho, DL Marks, EJ Tolosa, A Vedder, ...
Nature communications 12 (1), 2901, 2021
512021
Clinicopathologic characteristics, prognostication and treatment outcomes for myelodysplastic/myeloproliferative neoplasm, unclassifiable (MDS/MPN-U): Mayo Clinic-Moffitt …
AA Mangaonkar, DM Swoboda, G Coltro, TL Lasho, PJ Novotny, ...
Leukemia 34 (2), 656-661, 2020
422020
LSD1, a double-edged sword, confers dynamic chromatin regulation but commonly promotes aberrant cell growth
MM Kozub, RM Carr, GL Lomberk, ME Fernandez-Zapico
F1000Research 6, 2017
402017
GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression
EJ Tolosa, MG Fernandez-Barrena, E Iguchi, AL McCleary-Wheeler, ...
Biochemical Journal 477 (17), 3131-3145, 2020
302020
Spectrum of abnormalities and clonal transformation in germline RUNX1 familial platelet disorder and a genomic comparative analysis with somatic RUNX1 mutations in MDS/MPN …
EC DiFilippo, G Coltro, RM Carr, AA Mangaonkar, M Binder, SP Khan, ...
Leukemia 34 (9), 2519-2524, 2020
292020
Targeting the metabolic pathway of human colon cancer overcomes resistance to TRAIL-induced apoptosis
RM Carr, G Qiao, J Qin, S Jayaraman, BS Prabhakar, AV Maker
Cell death discovery 2 (1), 1-13, 2016
282016
Prognostic impact and timing considerations for allogeneic hematopoietic stem cell transplantation in chronic myelomonocytic leukemia
P Pophali, A Matin, AA Mangaonkar, R Carr, M Binder, A Al-Kali, ...
Blood cancer journal 10 (11), 121, 2020
262020
IG20/MADD plays a critical role in glucose-induced insulin secretion
L Li, Y Wang, R Carr, CS Haddad, Z Li, L Qian, J Oberholzer, AV Maker, ...
Diabetes 63 (5), 1612-1623, 2014
232014
SF3B1-mutant CMML defines a predominantly dysplastic CMML subtype with a superior acute leukemia–free survival
K Wudhikarn, S Loghavi, AA Mangaonkar, A Al-Kali, M Binder, R Carr, ...
Blood Advances 4 (22), 5716-5721, 2020
222020
Culture media composition influences patient-derived organoid ability to predict therapeutic responses in gastrointestinal cancers
TL Hogenson, H Xie, WJ Phillips, MD Toruner, JJ Li, IP Horn, DJ Kennedy, ...
JCI insight 7 (22), 2022
202022
Bone marrow dendritic cell aggregates associate with systemic immune dysregulation in chronic myelomonocytic leukemia
AA Mangaonkar, KK Reichard, M Binder, G Coltro, TL Lasho, RM Carr, ...
Blood Advances 4 (21), 5425-5430, 2020
192020
Epigenetics of cancer-associated muscle catabolism
RM Carr, E Enriquez-Hesles, RLO Olson, A Jatoi, J Doles, ...
Epigenomics 9 (10), 1259-1265, 2017
192017
Phase 1 trial of Vismodegib and Erlotinib combination in metastatic pancreatic cancer
AL McCleary-Wheeler, RM Carr, SR Palmer, TC Smyrk, JB Allred, ...
Pancreatology 20 (1), 101-109, 2020
182020
Oncogenic gene expression and epigenetic remodeling of cis-regulatory elements in ASXL1-mutant chronic myelomonocytic leukemia
M Binder, RM Carr, TL Lasho, CM Finke, AA Mangaonkar, CL Pin, ...
Nature communications 13 (1), 1434, 2022
142022
Targeting of the Hedgehog/GLI and mTOR pathways in advanced pancreatic cancer, a phase 1 trial of Vismodegib and Sirolimus combination
RM Carr, N Duma, AL McCleary-Wheeler, LL Almada, DL Marks, ...
Pancreatology 20 (6), 1115-1122, 2020
142020
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