| Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an … D Lamoral-Theys, A Andolfi, G Van Goietsenoven, A Cimmino, B Le Calvé, ... Journal of medicinal chemistry 52 (20), 6244-6256, 2009 | 298 | 2009 |
| Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence C Wiel, H Lallet-Daher, D Gitenay, B Gras, B Le Calvé, A Augert, ... Nature communications 5 (1), 3792, 2014 | 178 | 2014 |
| Long-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme … B Le Calvé, M Rynkowski, M Le Mercier, C Bruyère, C Lonez, T Gras, ... Neoplasia 12 (9), 727-739, 2010 | 153 | 2010 |
| 7-((4-Substituted) piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents J Azéma, B Guidetti, J Dewelle, B Le Calve, T Mijatovic, A Korolyov, ... Bioorganic & medicinal chemistry 17 (15), 5396-5407, 2009 | 115 | 2009 |
| Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway F Lessard, S Igelmann, C Trahan, G Huot, E Saint-Germain, L Mignacca, ... Nature cell biology 20 (7), 789-799, 2018 | 113 | 2018 |
| Transmembrane (TMEM) protein family members: Poorly characterized even if essential for the metastatic process S Marx, T Dal Maso, JW Chen, M Bury, J Wouters, C Michiels, B Le Calvé Seminars in cancer biology 60, 96-106, 2020 | 91 | 2020 |
| PLA2R1 mediates tumor suppression by activating JAK2 D Vindrieux, A Augert, CA Girard, D Gitenay, H Lallet-Daher, C Wiel, ... Cancer research 73 (20), 6334-6345, 2013 | 82 | 2013 |
| Structural simplification of bioactive natural products with multicomponent synthesis. 3. Fused uracil-containing heterocycles as novel topoisomerase-targeting agents NM Evdokimov, S Van Slambrouck, P Heffeter, L Tu, B Le Calve, ... Journal of medicinal chemistry 54 (7), 2012-2021, 2011 | 78 | 2011 |
| New insights into CDK regulators: novel opportunities for cancer therapy M Bury, B Le Calvé, G Ferbeyre, V Blank, F Lessard Trends in cell biology 31 (5), 331-344, 2021 | 73 | 2021 |
| NFE2L3 controls colon cancer cell growth through regulation of DUX4, a CDK1 inhibitor M Bury, B Le Calve, F Lessard, T Dal Maso, J Saliba, C Michiels, ... Cell Reports 29 (6), 1469-1481. e9, 2019 | 73 | 2019 |
| Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution B Le Calvé, A Griveau, D Vindrieux, R Maréchal, C Wiel, M Svrcek, J Gout, ... Oncotarget 7 (22), 32100, 2016 | 66 | 2016 |
| Proton irradiation orchestrates macrophage reprogramming through NFκB signaling G Genard, AC Wera, C Huart, B Le Calve, S Penninckx, A Fattaccioli, ... Cell death & disease 9 (7), 728, 2018 | 63 | 2018 |
| Potassium channel KCNA1 modulates oncogene-induced senescence and transformation H Lallet-Daher, C Wiel, D Gitenay, N Navaratnam, A Augert, B Le Calvé, ... Cancer research 73 (16), 5253-5265, 2013 | 49 | 2013 |
| PLA2R1 kills cancer cells by inducing mitochondrial stress A Augert, D Vindrieux, CA Girard, B Le Calvé, B Gras, M Ferrand, ... Free Radical Biology and Medicine 65, 969-977, 2013 | 42 | 2013 |
| Circumventing senescence is associated with stem cell properties and metformin sensitivity X Deschênes‐Simard, M Parisotto, MC Rowell, B Le Calvé, S Igelmann, ... Aging Cell 18 (2), e12889, 2019 | 38 | 2019 |
| Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth D Vindrieux, G Devailly, A Augert, B Le Calvé, M Ferrand, P Pigny, ... Oncotarget 5 (4), 1004, 2014 | 35 | 2014 |
| Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes A Griveau, C Wiel, B Le Calvé, DV Ziegler, S Djebali, M Warnier, N Martin, ... Aging Cell 17 (6), e12835, 2018 | 33 | 2018 |
| Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis C Wiel, A Augert, DF Vincent, D Gitenay, D Vindrieux, B Le Calvé, V Arfi, ... Cell death & disease 4 (10), e855-e855, 2013 | 32 | 2013 |
| Long-term temozolomide treatment induces marked amino metabolism modifications and an increase in TMZ sensitivity in Hs683 oligodendroglioma cells D Lamoral-Theys, M Le Mercier, B Le Calvé, MA Rynkowski, C Bruyère, ... Neoplasia 12 (1), 69-79, 2010 | 29 | 2010 |
| Synthesis and antitumor evaluation of analogues of the marine pyrroloiminoquinone tsitsikammamines A Rives, B Le Calvé, T Delaine, L Legentil, R Kiss, E Delfourne European journal of medicinal chemistry 45 (1), 343-351, 2010 | 22 | 2010 |
