|Mutations in ADAR1 cause Aicardi-Goutieres syndrome associated with a type I interferon signature|
GI Rice, PR Kasher, GMA Forte, NM Mannion, SM Greenwood, ...
Nature genetics 44 (11), 1243-1248, 2012
|A-to-I pre-mRNA editing in Drosophila is primarily involved in adult nervous system function and integrity|
MJ Palladino, LP Keegan, MA O'connell, RA Reenan
Cell 102 (4), 437-449, 2000
|Role of trans fatty acids in the nutritional regulation of mammary lipogenesis in ruminants|
KJ Shingfield, L Bernard, C Leroux, Y Chilliard
Animal 4 (7), 1140-1166, 2010
|The many roles of an RNA editor|
LP Keegan, A Gallo, MA O'Connell
Nature Reviews Genetics 2 (11), 869-878, 2001
|The RNA-editing enzyme ADAR1 controls innate immune responses to RNA|
NM Mannion, SM Greenwood, R Young, S Cox, J Brindle, D Read, ...
Cell reports 9 (4), 1482-1494, 2014
|Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase.|
MA O'Connell, S Krause, M Higuchi, JJ Hsuan, NF Totty, A Jenny, ...
Molecular and cellular biology 15 (3), 1389-1397, 1995
|Identifying RNA editing sites using RNA sequencing data alone|
G Ramaswami, R Zhang, R Piskol, LP Keegan, P Deng, MA O'connell, ...
Nature methods 10 (2), 128-132, 2013
|Dynamic association of RNA-editing enzymes with the nucleolus|
JMP Desterro, LP Keegan, M Lafarga, MT Berciano, M O'Connell, ...
Journal of cell science 116 (9), 1805-1818, 2003
|A standardized nomenclature for adenosine deaminases that act on RNA.|
BL Bass, K Nishikura, W Keller, PH Seeburg, RB Emeson, MA O'connell, ...
Rna 3 (9), 947, 1997
|Two forms of human double-stranded RNA-specific editase 1 (hRED1) generated by the insertion of an Alu cassette.|
A Gerber, MA O'Connell, W Keller
Rna 3 (5), 453, 1997
|Down-regulation of RNA editing in pediatric astrocytomas: ADAR2 editing activity inhibits cell migration and proliferation|
C Cenci, R Barzotti, F Galeano, S Corbelli, R Rota, L Massimi, C Di Rocco, ...
Journal of Biological Chemistry 283 (11), 7251-7260, 2008
|dADAR, a Drosophila double-stranded RNA-specific adenosine deaminase is highly developmentally regulated and is itself a target for RNA editing.|
MJ Palladino, LP Keegan, MA O'Connell, RA Reenan
Rna 6 (7), 1004-1018, 2000
|Editing independent effects of ADARs on the miRNA/siRNA pathways|
BSE Heale, LP Keegan, L McGurk, G Michlewski, J Brindle, CM Stanton, ...
The EMBO journal 28 (20), 3145-3156, 2009
|Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes|
LP Keegan, A Leroy, D Sproul, MA O'Connell
Genome biology 5 (2), 1-10, 2004
|Structural requirements for RNA editing in glutamate receptor pre-mRNAs by recombinant double-stranded RNA adenosine deaminase|
S Maas, T Melcher, A Herb, PH Seeburg, W Keller, S Krause, M Higuchi, ...
Journal of Biological Chemistry 271 (21), 12221-12226, 1996
|An ADAR that edits transcripts encoding ion channel subunits functions as a dimer|
A Gallo, LP Keegan, GM Ring, MA O'Connell
The EMBO journal 22 (13), 3421-3430, 2003
|SUMO-1 modification alters ADAR1 editing activity|
JMP Desterro, LP Keegan, E Jaffray, RT Hay, MA O'Connell, ...
Molecular biology of the cell 16 (11), 5115-5126, 2005
|Purification and properties of double-stranded RNA-specific adenosine deaminase from calf thymus|
MA O'Connell, W Keller
Proceedings of the National Academy of Sciences 91 (22), 10596-10600, 1994
|Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effects|
R Marcucci, J Brindle, S Paro, A Casadio, S Hempel, N Morrice, A Bisso, ...
The EMBO journal 30 (20), 4211-4222, 2011
|Purification of human double-stranded RNA-specific editase 1 (hRED1) involved in editing of brain glutamate receptor B pre-mRNA|
MA O'Connell, A Gerber, W Keller
Journal of Biological Chemistry 272 (1), 473-478, 1997