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Shoa L. Clarke
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GREAT improves functional interpretation of cis-regulatory regions
CY McLean, D Bristor, M Hiller, SL Clarke, BT Schaar, CB Lowe, ...
Nature biotechnology 28 (5), 495-501, 2010
43262010
The power of genetic diversity in genome-wide association studies of lipids
SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ...
Nature 600 (7890), 675-679, 2021
4602021
Coding exons function as tissue-specific enhancers of nearby genes
RY Birnbaum, EJ Clowney, O Agamy, MJ Kim, J Zhao, T Yamanaka, ...
Genome research 22 (6), 1059-1068, 2012
2592012
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations
C Tcheandjieu, X Zhu, AT Hilliard, SL Clarke, V Napolioni, S Ma, KM Lee, ...
Nature medicine 28 (8), 1679-1692, 2022
1422022
Human developmental enhancers conserved between deuterostomes and protostomes
SL Clarke, JE VanderMeer, AM Wenger, BT Schaar, N Ahituv, G Bejerano
PLoS genetics 8 (8), e1002852, 2012
802012
A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease
AP Patel, M Wang, Y Ruan, S Koyama, SL Clarke, X Yang, C Tcheandjieu, ...
Nature Medicine 29 (7), 1793-1803, 2023
602023
Validation of an integrated risk tool, including polygenic risk score, for atherosclerotic cardiovascular disease in multiple ethnicities and ancestries
ME Weale, F Riveros-Mckay, S Selzam, P Seth, R Moore, WA Tarran, ...
The American journal of cardiology 148, 157-164, 2021
582021
Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits
RA Patel, SA Musharoff, JP Spence, H Pimentel, C Tcheandjieu, ...
The American Journal of Human Genetics 109 (7), 1286-1297, 2022
50*2022
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential
T Nakao, AG Bick, MA Taub, SM Zekavat, MM Uddin, A Niroula, CL Carty, ...
Science advances 8 (14), eabl6579, 2022
45*2022
Genome-wide association studies of coronary artery disease: recent progress and challenges ahead
SL Clarke, TL Assimes
Current atherosclerosis reports 20, 1-11, 2018
392018
PRISM offers a comprehensive genomic approach to transcription factor function prediction
AM Wenger, SL Clarke, H Guturu, J Chen, BT Schaar, CY McLean, ...
Genome research 23 (5), 889-904, 2013
382013
Combining Clinical and Polygenic Risk Improves Stroke Prediction Among Individuals With Atrial Fibrillation
JW O'Sullivan, A Shcherbina, JM Justesen, M Turakhia, M Perez, H Wand, ...
Circulation: Genomic and Precision Medicine 14 (e003168), 2021
372021
Familial hypercholesterolemia
HE Ison, SL Clarke, JW Knowles
362022
ZEB2 Shapes the Epigenetic Landscape of Atherosclerosis
P Cheng, RC Wirka, L Shoa Clarke, Q Zhao, R Kundu, T Nguyen, S Nair, ...
Circulation 145 (6), 469-485, 2022
342022
The enhancer landscape during early neocortical development reveals patterns of dense regulation and co-option
AM Wenger, SL Clarke, JH Notwell, T Chung, G Tuteja, H Guturu, ...
PLoS genetics 9 (8), e1003728, 2013
342013
Control of pelvic girdle development by genes of the Pbx family and Emx2
TD Capellini, K Handschuh, L Quintana, E Ferretti, G Di Giacomo, ...
Developmental Dynamics 240 (5), 1173-1189, 2011
332011
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
S Kanoni, SE Graham, Y Wang, I Surakka, S Ramdas, X Zhu, SL Clarke, ...
Genome biology 23 (1), 268, 2022
272022
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
S Ramdas, J Judd, SE Graham, S Kanoni, Y Wang, I Surakka, B Wenz, ...
The American Journal of Human Genetics 109 (8), 1366-1387, 2022
272022
Cardiorespiratory fitness, body mass index, and markers of insulin resistance in apparently healthy women and men
SL Clarke, GM Reaven, D Leonard, CE Barlow, WL Haskell, BL Willis, ...
The American journal of medicine 133 (7), 825-830. e2, 2020
262020
Confounders mediate AI prediction of demographics in medical imaging
G Duffy, SL Clarke, M Christensen, B He, N Yuan, S Cheng, D Ouyang
NPJ digital medicine 5 (1), 188, 2022
222022
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