Segui
Youjun Chen
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Anno
The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex
Y Yokota, WY Kim, Y Chen, X Wang, A Stanco, Y Komuro, W Snider, ...
Neuron 61 (1), 42-56, 2009
1392009
Pten mutations alter brain growth trajectory and allocation of cell types through elevated β-catenin signaling
Y Chen, WC Huang, J Séjourné, AE Clipperton-Allen, DT Page
Journal of Neuroscience 35 (28), 10252-10267, 2015
1032015
Hyperconnectivity of prefrontal cortex to amygdala projections in a mouse model of macrocephaly/autism syndrome
WC Huang, Y Chen, DT Page
Nature Communications 7, 13421, 2016
1012016
Aggregation of the nucleic acid–binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation
Y Chen, TJ Cohen
Journal of Biological Chemistry, jbc. RA118. 006351, 2019
922019
Nucleocytoplasmic Shuttling of Receptor-interacting Protein 3 (RIP3)
Y Yang, J Ma, Y Chen, M Wu
Journal of Biological Chemistry 279 (37), 38820-38829, 2004
682004
An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline
H Trzeciakiewicz, D Ajit, JH Tseng, Y Chen, A Ajit, Z Tabassum, ...
Nature Communications 11 (1), 1-18, 2020
652020
Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease
S Swarnkar, Y Chen, WM Pryor, N Shahani, DT Page, S Subramaniam
Neurobiology of disease 82, 66-77, 2015
472015
Adenomatous Polyposis Coli Regulates Axon Arborization and Cytoskeleton Organization via Its N-Terminus
Y Chen, X Tian, WY Kim, WD Snider
PloS one 6 (9), e24335, 2011
322011
E2F1 inhibits MDM2 expression in a p53-dependent manner
X Tian, Y Chen, W Hu, M Wu
Cellular signalling 23 (1), 193-200, 2011
222011
Autism‐relevant behaviors are minimally impacted by conditional deletion of Pten in oxytocinergic neurons
AE Clipperton‐Allen, Y Chen, DT Page
Autism Research 9 (12), 1248-1262, 2016
192016
Tau seeds are subject to aberrant modifications resulting in distinct signatures
JH Tseng, A Ajit, Z Tabassum, N Patel, X Tian, Y Chen, AW Prevatte, ...
Cell Reports 35 (4), 109037, 2021
172021
A unique tau conformation generated by an acetylation-mimic substitution modulates P301S-dependent tau pathology and hyperphosphorylation
D Ajit, H Trzeciakiewicz, JH Tseng, CM Wander, Y Chen, A Ajit, DP King, ...
Journal of Biological Chemistry, jbc. RA119. 009674, 2019
142019
Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium
X Tian, K Patel, JR Ridpath, Y Chen, YH Zhou, D Neo, J Clement, ...
PloS one 11 (12), e0167503, 2016
142016
Genomic and Proteomic Mechanisms and Models in Toxicity and Safety Evaluation of Nutraceuticals
BM Kadakkuzha, X Liu, S Swarnkar, Y Chen
Nutraceuticals: Efficacy, Safety and Toxicity, 227-237, 2016
102016
RNA-binding deficient TDP-43 drives cognitive decline in a mouse model of TDP-43 proteinopathy
J Necarsulmer, J Simon, B Evangelista, Y Chen, X Tian, S Nafees, ...
eLife 12, 2023
72023
Genetic Suppression of mTOR Rescues Synaptic and Social Behavioral Abnormalities in a Mouse Model of Pten Haploinsufficiency
WC Huang, Y Chen, DT Page
Autism Research, 2019
52019
Activity-dependent tau cleavage by caspase-3 promotes neuronal dysfunction and synaptotoxicity
CK Opland, MR Bryan, B Harris, J McGillion-Moore, X Tian, Y Chen, ...
Iscience 26 (6), 2023
32023
Identification of a reciprocal negative feedback loop between tau-modifying proteins MARK2 kinase and CBP acetyltransferase
Z Tabassum, JH Tseng, C Isemann, X Tian, Y Chen, LE Herring, ...
Journal of Biological Chemistry 298 (6), 2022
22022
Recent Advances in Alzheimer's Drug Discovery Research
SVP Xin-An Liu, Brati Das, Youjun Chen, Zuxin Chen, Yosef Avchalumov, Xu Tian
Frontiers in Clinical Drug Research-Alzheimer Disorders: Volume 7 7, 2018
1*2018
A Distinct Tau Code Controlled by HDAC6 is Linked to Tau Pathogenesis and the Neuronal Stress Response
JH Tseng, A Ajit, Z Tabassum, N Patel, X Tian, Y Chen, AW Prevatte, ...
Available at SSRN 3618575, 2020
2020
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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