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Guillaume Hautbergue
Guillaume Hautbergue
Professor of Translational RNA Biology - SITraN - University of Sheffield
Email verificata su sheffield.ac.uk - Home page
Titolo
Citata da
Citata da
Anno
A simple method for improving protein solubility and long-term stability
AP Golovanov, GM Hautbergue, SA Wilson, LY Lian
Journal of the American Chemical Society 126 (29), 8933-8939, 2004
5732004
The C9orf72 protein interacts with Rab1a and the ULK 1 complex to regulate initiation of autophagy
CP Webster, EF Smith, CS Bauer, A Moller, GM Hautbergue, L Ferraiuolo, ...
The EMBO journal 35 (15), 1656-1676, 2016
4162016
Applications of machine learning to diagnosis and treatment of neurodegenerative diseases
MA Myszczynska, PN Ojamies, AMB Lacoste, D Neil, A Saffari, R Mead, ...
Nature Reviews Neurology 16 (8), 440-456, 2020
3702020
Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions
J Cooper-Knock, MJ Walsh, A Higginbottom, J Robin Highley, ...
Brain 137 (7), 2040-2051, 2014
3442014
Mutually exclusive interactions drive handover of mRNA from export adaptors to TAP
GM Hautbergue, ML Hung, AP Golovanov, LY Lian, SA Wilson
Proceedings of the National Academy of Sciences 105 (13), 5154-5159, 2008
2132008
TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export
N Viphakone, GM Hautbergue, M Walsh, CT Chang, A Holland, EG Folco, ...
Nature communications 3 (1), 1006, 2012
2052012
Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy
J Cooper-Knock, A Higginbottom, MJ Stopford, JR Highley, PG Ince, ...
Acta neuropathologica 130, 63-75, 2015
1932015
Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8
Y Hargous, GM Hautbergue, AM Tintaru, L Skrisovska, AP Golovanov, ...
The EMBO journal 25 (21), 5126-5137, 2006
1932006
C9ORF72 GGGGCC expanded repeats produce splicing dysregulation which correlates with disease severity in amyotrophic lateral sclerosis
J Cooper-Knock, JJ Bury, PR Heath, M Wyles, A Higginbottom, ...
PloS one 10 (5), e0127376, 2015
1792015
C9orf72 expansion disrupts ATM-mediated chromosomal break repair
C Walker, S Herranz-Martin, E Karyka, C Liao, K Lewis, W Elsayed, ...
Nature neuroscience 20 (9), 1225-1235, 2017
1712017
Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS
A Varcianna, MA Myszczynska, LM Castelli, B O'Neill, Y Kim, J Talbot, ...
EBioMedicine 40, 626-635, 2019
1612019
Ribosome-inactivating proteins: Potent poisons and molecular tools
MJ Walsh, JE Dodd, GM Hautbergue
Virulence 4 (8), 774-784, 2013
1612013
UIF, a New mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA
GM Hautbergue, ML Hung, MJ Walsh, APL Snijders, CT Chang, R Jones, ...
Current Biology 19 (22), 1918-1924, 2009
1532009
Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs
P Knuckles, MA Vogt, S Lugert, M Milo, MMW Chong, GM Hautbergue, ...
Nature neuroscience 15 (7), 962-969, 2012
1402012
SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits
GM Hautbergue, LM Castelli, L Ferraiuolo, A Sanchez-Martinez, ...
Nature communications 8 (1), 16063, 2017
1302017
Chtop is a component of the dynamic TREX mRNA export complex
CT Chang, GM Hautbergue, MJ Walsh, N Viphakone, TB Van Dijk, ...
The EMBO journal 32 (3), 473-486, 2013
1262013
A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A
A Cruz-Migoni, GM Hautbergue, PJ Artymiuk, PJ Baker, M Bokori-Brown, ...
Science 334 (6057), 821-824, 2011
1262011
Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis
SP Allen, B Hall, LM Castelli, L Francis, R Woof, AP Siskos, E Kouloura, ...
Brain 142 (3), 586-605, 2019
982019
Structural and functional analysis of RNA and TAP binding to SF2/ASF
AM Tintaru, GM Hautbergue, AM Hounslow, ML Hung, LY Lian, ...
EMBO reports 8 (8), 756-762, 2007
932007
The prototype γ-2 herpesvirus nucleocytoplasmic shuttling protein, ORF 57, transports viral RNA through the cellular mRNA export pathway
BJL Williams, JR Boyne, DJ Goodwin, L Roaden, GM Hautbergue, ...
Biochemical Journal 387 (2), 295-308, 2005
922005
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
Articoli 1–20