| Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure− activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors S Pasquini, C Mugnaini, C Tintori, M Botta, A Trejos, RK Arvela, M Larhed, ... Journal of medicinal chemistry 51 (16), 5125-5129, 2008 | 150 | 2008 |
| Pyrazolo [3, 4-d] pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation F Carraro, A Naldini, A Pucci, GA Locatelli, G Maga, S Schenone, O Bruno, ... Journal of medicinal chemistry 49 (5), 1549-1561, 2006 | 94 | 2006 |
| Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo [3, 4-d] pyrimidines S Schenone, C Brullo, O Bruno, F Bondavalli, L Mosti, G Maga, E Crespan, ... European journal of medicinal chemistry 43 (12), 2665-2676, 2008 | 81 | 2008 |
| Identification of new aminoacid amides containing the imidazo [2, 1-b] benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signaling A Furlan, F Colombo, A Kover, N Issaly, C Tintori, L Angeli, V Leroux, ... European journal of medicinal chemistry 47, 239-254, 2012 | 74 | 2012 |
| Design, Synthesis, Biological Activity, and ADME Properties of Pyrazolo[3,4-d]pyrimidines Active in Hypoxic Human Leukemia Cells: A Lead Optimization Study M Radi, E Dreassi, C Brullo, E Crespan, C Tintori, V Bernardo, M Valoti, ... Journal of medicinal chemistry 54 (8), 2610-2626, 2011 | 68 | 2011 |
| Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents A Brai, R Fazi, C Tintori, C Zamperini, F Bugli, M Sanguinetti, E Stigliano, ... Proceedings of the National Academy of Sciences 113 (19), 5388-5393, 2016 | 66 | 2016 |
| Antiproliferative and proapoptotic activities of new pyrazolo[3,4‐d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells A Spreafico, S Schenone, T Serchi, M Orlandini, A Angelucci, D Magrini, ... The FASEB Journal 22 (5), 1560-1571, 2008 | 66 | 2008 |
| Synthesis and 3D QSAR of new pyrazolo [3, 4-b] pyridines: potent and selective inhibitors of A1 adenosine receptors F Manetti, S Schenone, F Bondavalli, C Brullo, O Bruno, A Ranise, L Mosti, ... Journal of medicinal chemistry 48 (23), 7172-7185, 2005 | 60 | 2005 |
| Targets looking for drugs: a multistep computational protocol for the development of structure-based pharmacophores and their applications for hit discovery C Tintori, V Corradi, M Magnani, F Manetti, M Botta Journal of chemical information and modeling 48 (11), 2166-2179, 2008 | 57 | 2008 |
| The anti-HIV activity of ADS-J1 targets the HIV-1 gp120 M Armand-Ugón, I Clotet-Codina, C Tintori, F Manetti, B Clotet, M Botta, ... Virology 343 (1), 141-149, 2005 | 56 | 2005 |
| Exploration of novel thiobarbituric acid-, rhodanine-and thiohydantoin-based HIV-1 integrase inhibitors S Rajamaki, A Innitzer, C Falciani, C Tintori, F Christ, M Witvrouw, ... Bioorganic & medicinal chemistry letters 19 (13), 3615-3618, 2009 | 53 | 2009 |
| Toward novel HIV-1 integrase binding inhibitors: molecular modeling, synthesis, and biological studies C Mugnaini, S Rajamaki, C Tintori, F Corelli, S Massa, M Witvrouw, ... Bioorganic & medicinal chemistry letters 17 (19), 5370-5373, 2007 | 47 | 2007 |
| Docking, 3D-QSAR studies and in silico ADME prediction on c-Src tyrosine kinase inhibitors C Tintori, M Magnani, S Schenone, M Botta European journal of medicinal chemistry 44 (3), 990-1000, 2009 | 44 | 2009 |
| Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells M Radi, C Brullo, E Crespan, C Tintori, F Musumeci, M Biava, S Schenone, ... Bioorganic & medicinal chemistry letters 21 (19), 5928-5933, 2011 | 42 | 2011 |
| Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against … C Tintori, AL Fallacara, M Radi, C Zamperini, E Dreassi, E Crespan, ... Journal of medicinal chemistry 58 (1), 347-361, 2015 | 41 | 2015 |
| Development of an AlphaScreen-based HIV-1 integrase dimerization assay for discovery of novel allosteric inhibitors J Demeulemeester, C Tintori, M Botta, Z Debyser, F Christ Journal of biomolecular screening 17 (5), 618-628, 2012 | 41 | 2012 |
| 4, 6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA–PB1 Protein–Protein Interaction: Structure–Activity Relationships Exploration with the Aid of … IML Trist, G Nannetti, C Tintori, AL Fallacara, D Deodato, B Mercorelli, ... Journal of medicinal chemistry 59 (6), 2688-2703, 2016 | 39 | 2016 |
| Identification of Hck inhibitors as hits for the development of antileukemia and anti-HIV agents C Tintori, I Laurenzana, F La Rocca, F Falchi, F Carraro, A Ruiz, JA Esté, ... ChemMedChem 8 (8), 1353-1360, 2013 | 35 | 2013 |
| Design, Synthesis, and Biological Evaluation of Pyrazolo[3,4-d]pyrimidines Active in Vivo on the Bcr-Abl T315I Mutant M Radi, C Tintori, F Musumeci, C Brullo, C Zamperini, E Dreassi, ... Journal of medicinal chemistry 56 (13), 5382-5394, 2013 | 35 | 2013 |
| Discovery of small molecule HIV-1 integrase dimerization inhibitors C Tintori, J Demeulemeester, L Franchi, S Massa, Z Debyser, F Christ, ... Bioorganic & medicinal chemistry letters 22 (9), 3109-3114, 2012 | 32 | 2012 |
Giovanni MagaIGM CNRVerified email at igm.cnr.it
