cristina tintori
cristina tintori
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Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure− activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors
S Pasquini, C Mugnaini, C Tintori, M Botta, A Trejos, RK Arvela, M Larhed, ...
Journal of medicinal chemistry 51 (16), 5125-5129, 2008
Pyrazolo [3, 4-d] pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation
F Carraro, A Naldini, A Pucci, GA Locatelli, G Maga, S Schenone, O Bruno, ...
Journal of medicinal chemistry 49 (5), 1549-1561, 2006
Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo [3, 4-d] pyrimidines
S Schenone, C Brullo, O Bruno, F Bondavalli, L Mosti, G Maga, E Crespan, ...
European journal of medicinal chemistry 43 (12), 2665-2676, 2008
Identification of new aminoacid amides containing the imidazo [2, 1-b] benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signaling
A Furlan, F Colombo, A Kover, N Issaly, C Tintori, L Angeli, V Leroux, ...
European journal of medicinal chemistry 47, 239-254, 2012
Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents
A Brai, R Fazi, C Tintori, C Zamperini, F Bugli, M Sanguinetti, E Stigliano, ...
Proceedings of the National Academy of Sciences 113 (19), 5388-5393, 2016
Design, Synthesis, Biological Activity, and ADME Properties of Pyrazolo[3,4-d]pyrimidines Active in Hypoxic Human Leukemia Cells: A Lead Optimization Study
M Radi, E Dreassi, C Brullo, E Crespan, C Tintori, V Bernardo, M Valoti, ...
Journal of medicinal chemistry 54 (8), 2610-2626, 2011
Antiproliferative and proapoptotic activities of new pyrazolo[3,4‐d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells
A Spreafico, S Schenone, T Serchi, M Orlandini, A Angelucci, D Magrini, ...
The FASEB Journal 22 (5), 1560-1571, 2008
Targets looking for drugs: a multistep computational protocol for the development of structure-based pharmacophores and their applications for hit discovery
C Tintori, V Corradi, M Magnani, F Manetti, M Botta
Journal of chemical information and modeling 48 (11), 2166-2179, 2008
Synthesis and 3D QSAR of new pyrazolo [3, 4-b] pyridines: potent and selective inhibitors of A1 adenosine receptors
F Manetti, S Schenone, F Bondavalli, C Brullo, O Bruno, A Ranise, L Mosti, ...
Journal of medicinal chemistry 48 (23), 7172-7185, 2005
The anti-HIV activity of ADS-J1 targets the HIV-1 gp120
M Armand-Ugˇn, I Clotet-Codina, C Tintori, F Manetti, B Clotet, M Botta, ...
Virology 343 (1), 141-149, 2005
Exploration of novel thiobarbituric acid-, rhodanine-and thiohydantoin-based HIV-1 integrase inhibitors
S Rajamaki, A Innitzer, C Falciani, C Tintori, F Christ, M Witvrouw, ...
Bioorganic & medicinal chemistry letters 19 (13), 3615-3618, 2009
Toward novel HIV-1 integrase binding inhibitors: molecular modeling, synthesis, and biological studies
C Mugnaini, S Rajamaki, C Tintori, F Corelli, S Massa, M Witvrouw, ...
Bioorganic & medicinal chemistry letters 17 (19), 5370-5373, 2007
Docking, 3D-QSAR studies and in silico ADME prediction on c-Src tyrosine kinase inhibitors
C Tintori, M Magnani, S Schenone, M Botta
European journal of medicinal chemistry 44 (3), 990-1000, 2009
Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells
M Radi, C Brullo, E Crespan, C Tintori, F Musumeci, M Biava, S Schenone, ...
Bioorganic & medicinal chemistry letters 21 (19), 5928-5933, 2011
Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo againstá…
C Tintori, AL Fallacara, M Radi, C Zamperini, E Dreassi, E Crespan, ...
Journal of medicinal chemistry 58 (1), 347-361, 2015
Development of an AlphaScreen-based HIV-1 integrase dimerization assay for discovery of novel allosteric inhibitors
J Demeulemeester, C Tintori, M Botta, Z Debyser, F Christ
Journal of biomolecular screening 17 (5), 618-628, 2012
4, 6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA–PB1 Protein–Protein Interaction: Structure–Activity Relationships Exploration with the Aid ofá…
IML Trist, G Nannetti, C Tintori, AL Fallacara, D Deodato, B Mercorelli, ...
Journal of medicinal chemistry 59 (6), 2688-2703, 2016
Identification of Hck inhibitors as hits for the development of antileukemia and anti-HIV agents
C Tintori, I Laurenzana, F La Rocca, F Falchi, F Carraro, A Ruiz, JA EstÚ, ...
ChemMedChem 8 (8), 1353-1360, 2013
Design, Synthesis, and Biological Evaluation of Pyrazolo[3,4-d]pyrimidines Active in Vivo on the Bcr-Abl T315I Mutant
M Radi, C Tintori, F Musumeci, C Brullo, C Zamperini, E Dreassi, ...
Journal of medicinal chemistry 56 (13), 5382-5394, 2013
Novel virtual screening protocol based on the combined use of molecular modeling and electron-ion interaction potential techniques to design HIV-1 integrase inhibitors
C Tintori, F Manetti, N Veljkovic, V Perovic, J Vercammen, S Hayes, ...
Journal of chemical information and modeling 47 (4), 1536-1544, 2007
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