Piezo1 integration of vascular architecture with physiological force J Li, B Hou, S Tumova, K Muraki, A Bruns, MJ Ludlow, A Sedo, AJ Hyman, ... Nature 515 (7526), 279-282, 2014 | 980 | 2014 |
Yoda1 analogue (D ooku1) which antagonizes Y oda1‐evoked activation of P iezo1 and aortic relaxation EL Evans, K Cuthbertson, N Endesh, B Rode, NM Blythe, AJ Hyman, ... British journal of pharmacology 175 (10), 1744-1759, 2018 | 162 | 2018 |
Piezo1 channels in vascular development and the sensing of shear stress AJ Hyman, S Tumova, DJ Beech Current topics in membranes 79, 37-57, 2017 | 76 | 2017 |
Piezo1 channels are mechanosensors in human fetoplacental endothelial cells LC Morley, J Shi, HJ Gaunt, AJ Hyman, PJ Webster, C Williams, K Forbes, ... MHR: Basic science of reproductive medicine 24 (10), 510-520, 2018 | 61 | 2018 |
Sphingomyelinase disables inactivation in endogenous PIEZO1 channels J Shi, AJ Hyman, D De Vecchis, J Chong, L Lichtenstein, TS Futers, ... Cell reports 33 (1), 2020 | 50 | 2020 |
Modeling of full-length Piezo1 suggests importance of the proximal N-terminus for dome structure J Chong, D De Vecchis, AJ Hyman, OV Povstyan, MJ Ludlow, J Shi, ... Biophysical journal 120 (8), 1343-1356, 2021 | 28 | 2021 |
Improved PIEZO1 agonism through 4‐benzoic acid modification of Yoda1 G Parsonage, K Cuthbertson, N Endesh, N Murciano, AJ Hyman, ... British Journal of Pharmacology 180 (16), 2039-2063, 2023 | 16 | 2023 |
Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases PJ Webster, AT Littlejohns, HJ Gaunt, RS Young, B Rode, JE Ritchie, ... Oncotarget 8 (26), 42288, 2017 | 12 | 2017 |
Computational reconstruction of the complete Piezo1 structure reveals a unique footprint and specific lipid interactions J Chong, D De Vecchis, AJ Hyman, OV Povstyan, J Shi, DJ Beech, ... BioRxiv, 783753, 2019 | 7 | 2019 |
Sphingomyelinase disables Piezo1 channel inactivation to enable sustained response to mechanical force J Shi, AJ Hyman, D De Vecchis, J Chong, L Lichtenstein, TS Futers, ... BioRxiv, 792564, 2019 | 4 | 2019 |
Resistance of store‐operated calcium entry to tumour microenvironment conditions and enhanced potency of Synta66 in colorectal adenocarcinoma cells (1057.4) H Appleby, H Gaunt, S Jansz, A Hyman, O Stokes, R Young, R Foster, ... The FASEB Journal 28, 1057.4, 2014 | 1 | 2014 |
PIEZO1 MECHANOSENSITIVE ION CHANNELS ARE REQUIRED FOR SHEAR STRESS SENSING IN PLACENTAL VASCULATURE L Morley, J Shi, H Gaunt, A Hyman, P Webster, K Forbes, J Walker, ... Placenta, 2018 | | 2018 |
Modulation of Piezo1 by lipids and synthetic small-molecules AJ Hyman University of Leeds, 2018 | | 2018 |