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Adam Hyman
Adam Hyman
Scientist, Charles River Labs
Verified email at crl.com
Title
Cited by
Cited by
Year
Piezo1 integration of vascular architecture with physiological force
J Li, B Hou, S Tumova, K Muraki, A Bruns, MJ Ludlow, A Sedo, AJ Hyman, ...
Nature 515 (7526), 279-282, 2014
9802014
Yoda1 analogue (D ooku1) which antagonizes Y oda1‐evoked activation of P iezo1 and aortic relaxation
EL Evans, K Cuthbertson, N Endesh, B Rode, NM Blythe, AJ Hyman, ...
British journal of pharmacology 175 (10), 1744-1759, 2018
1622018
Piezo1 channels in vascular development and the sensing of shear stress
AJ Hyman, S Tumova, DJ Beech
Current topics in membranes 79, 37-57, 2017
762017
Piezo1 channels are mechanosensors in human fetoplacental endothelial cells
LC Morley, J Shi, HJ Gaunt, AJ Hyman, PJ Webster, C Williams, K Forbes, ...
MHR: Basic science of reproductive medicine 24 (10), 510-520, 2018
612018
Sphingomyelinase disables inactivation in endogenous PIEZO1 channels
J Shi, AJ Hyman, D De Vecchis, J Chong, L Lichtenstein, TS Futers, ...
Cell reports 33 (1), 2020
502020
Modeling of full-length Piezo1 suggests importance of the proximal N-terminus for dome structure
J Chong, D De Vecchis, AJ Hyman, OV Povstyan, MJ Ludlow, J Shi, ...
Biophysical journal 120 (8), 1343-1356, 2021
282021
Improved PIEZO1 agonism through 4‐benzoic acid modification of Yoda1
G Parsonage, K Cuthbertson, N Endesh, N Murciano, AJ Hyman, ...
British Journal of Pharmacology 180 (16), 2039-2063, 2023
162023
Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases
PJ Webster, AT Littlejohns, HJ Gaunt, RS Young, B Rode, JE Ritchie, ...
Oncotarget 8 (26), 42288, 2017
122017
Computational reconstruction of the complete Piezo1 structure reveals a unique footprint and specific lipid interactions
J Chong, D De Vecchis, AJ Hyman, OV Povstyan, J Shi, DJ Beech, ...
BioRxiv, 783753, 2019
72019
Sphingomyelinase disables Piezo1 channel inactivation to enable sustained response to mechanical force
J Shi, AJ Hyman, D De Vecchis, J Chong, L Lichtenstein, TS Futers, ...
BioRxiv, 792564, 2019
42019
Resistance of store‐operated calcium entry to tumour microenvironment conditions and enhanced potency of Synta66 in colorectal adenocarcinoma cells (1057.4)
H Appleby, H Gaunt, S Jansz, A Hyman, O Stokes, R Young, R Foster, ...
The FASEB Journal 28, 1057.4, 2014
12014
PIEZO1 MECHANOSENSITIVE ION CHANNELS ARE REQUIRED FOR SHEAR STRESS SENSING IN PLACENTAL VASCULATURE
L Morley, J Shi, H Gaunt, A Hyman, P Webster, K Forbes, J Walker, ...
Placenta, 2018
2018
Modulation of Piezo1 by lipids and synthetic small-molecules
AJ Hyman
University of Leeds, 2018
2018
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