Fukushima Hidefumi

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Wenyi WeiProfessor, Dept. of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical SchoolVerified email at bidmc.harvard.edu
Lixin WanH. Lee Moffitt Cancer Center and Research InstituteVerified email at moffitt.org
Pengda LiuUniversity of North Carolina at Chapel HillVerified email at med.unc.edu
Alex TokerVerified email at bidmc.harvard.edu
Rebecca ChinAssociate professor of Biomedical Sciences, City University of Hong KongVerified email at cityu.edu.hk
Fulvio D'AcquistoProfessor of Immunology, University of RoehamptonVerified email at roehampton.ac.uk
Sankar Ghoshyale OR hhmi OR columbia OR einstein OR whiteheadVerified email at columbia.edu
Michael MayAssociate Professor, University of PennsylvaniaVerified email at vet.upenn.edu
Lewis CantleyDana Farber Cancer Center and Harvard Medical SchoolVerified email at med.cornell.edu
J.Wade HarperProfessor of Cell BiologyVerified email at hms.harvard.edu
Anna BigasGroup Leader and Coordinator, Stem Cells and Cancer group. Research Institute Hospital del Mar andVerified email at imim.es
Seiji SakanoDaicel CorporationVerified email at jp.daicel.com
Tetsu TakahashiProfessor and Chairman, Division of Oral and Maxillofacial Surgery, Tohoku University Graduate School of DentistryVerified email at dent.tohoku.ac.jp
Neil AllesProfessor in Biochemistry, Dept. of Biochemistry, Faculty of Medicine, University of peradeniyaVerified email at pdn.ac.lk
Pier Paolo PandolfiDirector, Cancer Center and Cancer Research Institute, Beth Israel Deaconess Medical CenterVerified email at bidmc.harvard.edu
Jack LawlerHarvard Medical SchoolVerified email at bidmc.harvard.edu
Akinobu MatsumotoNagoya UniversityVerified email at f.mail.nagoya-u.ac.jp
Marc KirschnerProfessor of Systems Biology, Harvard Medical SchoolVerified email at hms.harvard.edu
Pengbo LiuResearch Associate Professor, Globla Health, Emory UniversityVerified email at sph.emory.edu

Fukushima Hidefumi

Associate Professor, Center for Advanced Stem Cell and Regenerative Research, Tohoku University Graduate School of Dentistry

Verified email at tohoku.ac.jp

Bone Mineral Research osteoclast osteoblast Notch Ubiquitin Proteasome


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Selective inhibition of NF-κB blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo E Jimi, K Aoki, H Saito, F D'Acquisto, MJ May, I Nakamura, T Sudo, ... Nature medicine 10 (6), 617-624, 2004	623	2004
Lactobacillus reuteri in bovine milk fermented decreases the oral carriage of mutans streptococci H Nikawa, S Makihira, H Fukushima, H Nishimura, Y Ozaki, K Ishida, ... International journal of food microbiology 95 (2), 219-223, 2004	401	2004
mTOR drives its own activation via SCFβTrCP-dependent degradation of the mTOR inhibitor DEPTOR D Gao, H Inuzuka, MKM Tan, H Fukushima, JW Locasale, P Liu, L Wan, ... Molecular cell 44 (2), 290-303, 2011	269	2011
Acetylation-dependent regulation of Skp2 function H Inuzuka, D Gao, LWS Finley, W Yang, L Wan, H Fukushima, YR Chin, ... Cell 150 (1), 179-193, 2012	218	2012
The association of Notch2 and NF-κB accelerates RANKL-induced osteoclastogenesis H Fukushima, A Nakao, F Okamoto, M Shin, H Kajiya, S Sakano, A Bigas, ... Molecular and cellular biology, 2008	198	2008
Expression and role of RANKL in periodontal ligament cells during physiological root‐resorption in human deciduous teeth H Fukushima, H Kajiya, K Takada, F Okamoto, K Okabe European journal of oral sciences 111 (4), 346-352, 2003	185	2003
Tumor suppressor functions of FBW7 in cancer development and progression Z Wang, H Inuzuka, J Zhong, L Wan, H Fukushima, FH Sarkar, W Wei FEBS letters 586 (10), 1409-1418, 2012	181	2012
The current and future therapies of bone regeneration to repair bone defects E Jimi, S Hirata, K Osawa, M Terashita, C Kitamura, H Fukushima International journal of dentistry 2012, 2012	174	2012
Tumor necrosis factor α represses bone morphogenetic protein (BMP) signaling by interfering with the DNA binding of Smads through the activation of NF-κB M Yamazaki, H Fukushima, M Shin, T Katagiri, T Doi, T Takahashi, E Jimi Journal of Biological Chemistry 284 (51), 35987-35995, 2009	139	2009
Skp2: a novel potential therapeutic target for prostate cancer Z Wang, D Gao, H Fukushima, H Inuzuka, P Liu, L Wan, FH Sarkar, W Wei Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1825 (1), 11-17, 2012	138	2012
The Fbw7 and beta-TRCP E3 ubiquitin ligases and their roles in tumorigenesis AW Lau, H Fukushima, W Wei Frontiers in bioscience: a journal and virtual library 17, 2197, 2012	127	2012
Effects of high molecular weight component on crystallization of polyethylene under shear flow Y Ogino, H Fukushima, G Matsuba, N Takahashi, K Nishida, T Kanaya Polymer 47 (15), 5669-5677, 2006	125	2006
Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1 L Wan, W Zou, D Gao, H Inuzuka, H Fukushima, AH Berg, R Drapp, ... Molecular cell 44 (5), 721-733, 2011	109	2011
SCFFbw7 modulates the NFκB signaling pathway by targeting NFκB2 for ubiquitination and destruction H Fukushima, A Matsumoto, H Inuzuka, B Zhai, AW Lau, L Wan, D Gao, ... Cell reports 1 (5), 434-443, 2012	105	2012
Low‐level laser irradiation enhances BMP‐induced osteoblast differentiation by stimulating the BMP/Smad signaling pathway S Hirata, C Kitamura, H Fukushima, I Nakamichi, Y Abiko, M Terashita, ... Journal of cellular biochemistry 111 (6), 1445-1452, 2010	98	2010
SCF^β-TRCP suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2 S Shaik, C Nucera, H Inuzuka, D Gao, M Garnaas, G Frechette, L Harris, ... Journal of Experimental Medicine 209 (7), 1289-1307, 2012	93	2012
Mcl-1 ubiquitination and destruction H Inuzuka, H Fukushima, S Shaik, P Liu, AW Lau, W Wei Oncotarget 2 (3), 239, 2011	92	2011
IL-1-induced receptor activator of NF-κB ligand in human periodontal ligament cells involves ERK-dependent PGE2 production H Fukushima, E Jimi, F Okamoto, W Motokawa, K Okabe Bone 36 (2), 267-275, 2005	89	2005
Skp2 is a promising therapeutic target in breast cancer Z Wang, H Fukushima, H Inuzuka, L Wan, P Liu, D Gao, FH Sarkar, W Wei Frontiers in oncology 1, 57, 2012	87	2012
SCF-mediated Cdh1 degradation defines a negative feedback system that coordinates cell-cycle progression H Fukushima, K Ogura, L Wan, Y Lu, V Li, D Gao, P Liu, AW Lau, T Wu, ... Cell reports 4 (4), 803-816, 2013	85	2013

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