| Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of [alpha]-Ketoglutarate-Dependent Dioxygenases W Xu, H Yang, Y Liu, Y Yang, P Wang, SH Kim, S Ito, C Yang, P Wang, ... Cancer Cell 19 (1), 17-30, 2011 | 2091 | 2011 |
| In silico design of novel probes for the atypical opioid receptor MRGPRX2 K Lansu, J Karpiak, J Liu, XP Huang, JD McCorvy, WK Kroeze, T Che, ... Nature chemical biology 13 (5), 529-536, 2017 | 128 | 2017 |
| Synthesis of resveratrol using a direct decarbonylative Heck approach from resorcylic acid MB Andrus, J Liu, EL Meredith, E Nartey Tetrahedron letters 44 (26), 4819-4822, 2003 | 116 | 2003 |
| MERTK receptor tyrosine kinase is a therapeutic target in melanoma J Schlegel, MJ Sambade, S Sather, SJ Moschos, AC Tan, A Winges, ... The Journal of clinical investigation 123 (5), 2257-2267, 2013 | 112 | 2013 |
| A potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases MS Eram, Y Shen, MM Szewczyk, H Wu, G Senisterra, F Li, KV Butler, ... ACS chemical biology 11 (3), 772-781, 2016 | 109 | 2016 |
| UNC2025, a Potent and Orally Bioavailable MER/FLT3 Dual Inhibitor W Zhang, D DeRyckere, D Hunter, J Liu, MA Stashko, KA Minson, ... Journal of medicinal chemistry 57 (16), 7031-7041, 2014 | 90 | 2014 |
| Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia J Liu, C Yang, C Simpson, D DeRyckere, A Van Deusen, MJ Miley, ... ACS Medicinal Chemistry Letters 3 (2), 129-134, 2012 | 86 | 2012 |
| Proteolysis targeting chimeras (PROTACs) of anaplastic lymphoma kinase (ALK) C Zhang, XR Han, X Yang, B Jiang, J Liu, Y Xiong, J Jin European journal of medicinal chemistry 151, 304-314, 2018 | 84 | 2018 |
| UNC1062, a new and potent Mer inhibitor J Liu, W Zhang, MA Stashko, et al. European Journal of Medicinal Chemistry, 2013 | 72 | 2013 |
| DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in Vivo KJ Thompson, E Khajehali, SJ Bradley, JS Navarrete, XP Huang, ... ACS pharmacology & translational science 1 (1), 61-72, 2018 | 69 | 2018 |
| UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo S Christoph, D DeRyckere, J Schlegel, JK Frazer, LA Batchelor, ... Molecular cancer therapeutics 12 (11), 2367-2377, 2013 | 58 | 2013 |
| Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors F Liu, F Li, A Ma, E Dobrovetsky, A Dong, C Gao, I Korboukh, J Liu, D Smil, ... Journal of medicinal chemistry 56 (5), 2110-2124, 2013 | 56 | 2013 |
| A chemical biology toolbox to study protein methyltransferases and epigenetic signaling S Scheer, S Ackloo, TS Medina, M Schapira, F Li, JA Ward, AM Lewis, ... Nature communications 10 (1), 1-14, 2019 | 55 | 2019 |
| Synthesis of polyhydroxylated ester analogs of the stilbene resveratrol using decarbonylative Heck couplings MB Andrus, J Liu Tetrahedron letters 47 (32), 5811-5814, 2006 | 54 | 2006 |
| Structural determinants of 5-HT 2B receptor activation and biased agonism JD McCorvy, D Wacker, S Wang, B Agegnehu, J Liu, K Lansu, AR Tribo, ... Nature structural & molecular biology 25 (9), 787-796, 2018 | 47 | 2018 |
| Asymmetric glycolate aldol reactions using cinchonium phase-transfer catalysts MB Andrus, J Liu, Z Ye, JF Cannon Organic letters 7 (18), 3861-3864, 2005 | 41 | 2005 |
| Discovery of a potent, selective, and cell-active dual inhibitor of protein arginine methyltransferase 4 and protein arginine methyltransferase 6 Y Shen, MM Szewczyk, MS Eram, D Smil, HU Kaniskan, ... Journal of medicinal chemistry 59 (19), 9124-9139, 2016 | 40 | 2016 |
| Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia AB Lee-Sherick, W Zhang, KK Menachof, AA Hill, S Rinella, G Kirkpatrick, ... Oncotarget 6 (9), 6722, 2015 | 38 | 2015 |
| Discovery of potent and selective inhibitors for G9a-like protein (GLP) lysine methyltransferase Y Xiong, F Li, N Babault, A Dong, H Zeng, H Wu, X Chen, CH Arrowsmith, ... Journal of medicinal chemistry 60 (5), 1876-1891, 2017 | 36 | 2017 |
| Discovery of Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT) N Babault, A Allali-Hassani, F Li, J Fan, A Yue, K Ju, F Liu, M Vedadi, ... Journal of medicinal chemistry 61 (4), 1541-1551, 2018 | 26 | 2018 |
