Jing Liu
Jing Liu
Cullgen Inc.
Verified email at cullgen.com
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Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of [alpha]-Ketoglutarate-Dependent Dioxygenases
W Xu, H Yang, Y Liu, Y Yang, P Wang, SH Kim, S Ito, C Yang, P Wang, ...
Cancer Cell 19 (1), 17-30, 2011
In silico design of novel probes for the atypical opioid receptor MRGPRX2
K Lansu, J Karpiak, J Liu, XP Huang, JD McCorvy, WK Kroeze, T Che, ...
Nature chemical biology 13 (5), 529-536, 2017
Synthesis of resveratrol using a direct decarbonylative Heck approach from resorcylic acid
MB Andrus, J Liu, EL Meredith, E Nartey
Tetrahedron letters 44 (26), 4819-4822, 2003
MERTK receptor tyrosine kinase is a therapeutic target in melanoma
J Schlegel, MJ Sambade, S Sather, SJ Moschos, AC Tan, A Winges, ...
The Journal of clinical investigation 123 (5), 2257-2267, 2013
A potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases
MS Eram, Y Shen, MM Szewczyk, H Wu, G Senisterra, F Li, KV Butler, ...
ACS chemical biology 11 (3), 772-781, 2016
UNC2025, a Potent and Orally Bioavailable MER/FLT3 Dual Inhibitor
W Zhang, D DeRyckere, D Hunter, J Liu, MA Stashko, KA Minson, ...
Journal of medicinal chemistry 57 (16), 7031-7041, 2014
Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia
J Liu, C Yang, C Simpson, D DeRyckere, A Van Deusen, MJ Miley, ...
ACS Medicinal Chemistry Letters 3 (2), 129-134, 2012
Proteolysis targeting chimeras (PROTACs) of anaplastic lymphoma kinase (ALK)
C Zhang, XR Han, X Yang, B Jiang, J Liu, Y Xiong, J Jin
European journal of medicinal chemistry 151, 304-314, 2018
UNC1062, a new and potent Mer inhibitor
J Liu, W Zhang, MA Stashko, et al.
European Journal of Medicinal Chemistry, 2013
DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in Vivo
KJ Thompson, E Khajehali, SJ Bradley, JS Navarrete, XP Huang, ...
ACS pharmacology & translational science 1 (1), 61-72, 2018
UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo
S Christoph, D DeRyckere, J Schlegel, JK Frazer, LA Batchelor, ...
Molecular cancer therapeutics 12 (11), 2367-2377, 2013
Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors
F Liu, F Li, A Ma, E Dobrovetsky, A Dong, C Gao, I Korboukh, J Liu, D Smil, ...
Journal of medicinal chemistry 56 (5), 2110-2124, 2013
A chemical biology toolbox to study protein methyltransferases and epigenetic signaling
S Scheer, S Ackloo, TS Medina, M Schapira, F Li, JA Ward, AM Lewis, ...
Nature communications 10 (1), 1-14, 2019
Synthesis of polyhydroxylated ester analogs of the stilbene resveratrol using decarbonylative Heck couplings
MB Andrus, J Liu
Tetrahedron letters 47 (32), 5811-5814, 2006
Structural determinants of 5-HT 2B receptor activation and biased agonism
JD McCorvy, D Wacker, S Wang, B Agegnehu, J Liu, K Lansu, AR Tribo, ...
Nature structural & molecular biology 25 (9), 787-796, 2018
Asymmetric glycolate aldol reactions using cinchonium phase-transfer catalysts
MB Andrus, J Liu, Z Ye, JF Cannon
Organic letters 7 (18), 3861-3864, 2005
Discovery of a potent, selective, and cell-active dual inhibitor of protein arginine methyltransferase 4 and protein arginine methyltransferase 6
Y Shen, MM Szewczyk, MS Eram, D Smil, HU Kaniskan, ...
Journal of medicinal chemistry 59 (19), 9124-9139, 2016
Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia
AB Lee-Sherick, W Zhang, KK Menachof, AA Hill, S Rinella, G Kirkpatrick, ...
Oncotarget 6 (9), 6722, 2015
Discovery of potent and selective inhibitors for G9a-like protein (GLP) lysine methyltransferase
Y Xiong, F Li, N Babault, A Dong, H Zeng, H Wu, X Chen, CH Arrowsmith, ...
Journal of medicinal chemistry 60 (5), 1876-1891, 2017
Discovery of Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT)
N Babault, A Allali-Hassani, F Li, J Fan, A Yue, K Ju, F Liu, M Vedadi, ...
Journal of medicinal chemistry 61 (4), 1541-1551, 2018
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