| Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element ACG Kankanamalage, Y Kim, VC Damalanka, AD Rathnayake, AR Fehr, ... European journal of medicinal chemistry 150, 334-346, 2018 | 114 | 2018 |
| A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells M Matthew, CD Vishnu, T Michael, C Dong hee, L André Luiz, P Dustin, ... Proceedings of the National Academy of Sciences 118 (43), 1-12, 2021 | 71 | 2021 |
| Structure-guided design and optimization of dipeptidyl inhibitors of norovirus 3CL protease. Structure–activity relationships and biochemical, X-ray crystallographic, cell … AC Galasiti Kankanamalage, Y Kim, PM Weerawarna, RAZ Uy, ... Journal of medicinal chemistry 58 (7), 3144-3155, 2015 | 66 | 2015 |
| Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies PM Weerawarna, Y Kim, ACG Kankanamalage, VC Damalanka, ... European journal of medicinal chemistry 119, 300-318, 2016 | 43 | 2016 |
| Oxadiazole-based cell permeable macrocyclic transition state inhibitors of norovirus 3CL protease. VC Damalanka, K Y., AK Weerawarna P., G K. A., L G., M N., K B., L S., ... Abstracts of Papers, 251st ACS National Meeting & Exposition, San Diego, CA …, 2016 | 36 | 2016 |
| Oxadiazole-based cell permeable macrocyclic transition state inhibitors of norovirus 3CL protease VC Damalanka, Y Kim, KR Alliston, PM Weerawarna, ... Journal of medicinal chemistry 59 (5), 1899-1913, 2016 | 36 | 2016 |
| Potent inhibition of enterovirus D68 and human rhinoviruses by dipeptidyl aldehydes and α-ketoamides Y Kim, ACG Kankanamalage, VC Damalanka, PM Weerawarna, ... Antiviral research 125, 84-91, 2016 | 31 | 2016 |
| Discovery of selective matriptase and hepsin serine protease inhibitors: useful chemical tools for cancer cell biology VC Damalanka, Z Han, P Karmakar, AJ O’Donoghue, F La Greca, T Kim, ... Journal of medicinal chemistry 62 (2), 480-490, 2018 | 28 | 2018 |
| Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors ACG Kankanamalage, Y Kim, AD Rathnayake, VC Damalanka, ... European journal of medicinal chemistry 126, 502-516, 2017 | 26 | 2017 |
| Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease VC Damalanka, Y Kim, ACG Kankanamalage, GH Lushington, ... European journal of medicinal chemistry 127, 41-61, 2017 | 21 | 2017 |
| Recent progress on inhibitors of the type II transmembrane serine proteases, hepsin, matriptase and matriptase-2 VC Damalanka, JW Janetka Future medicinal chemistry 11 (7), 743-769, 2019 | 16 | 2019 |
| Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease VC Damalanka, Y Kim, ACG Kankanamalage, AD Rathnayake, ... European journal of medicinal chemistry 143, 881-890, 2018 | 16 | 2018 |
| Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin VC Damalanka, SA Wildman, JW Janetka MedChemComm 10 (9), 1646-1655, 2019 | 10 | 2019 |
| Macrocyclic inhibitors of HGF-activating serine proteases overcome resistance to receptor tyrosine kinase inhibitors and block lung cancer progression VC Damalanka, JJLP Voss, MW Mahoney, T Primeau, S Li, L Klampfer, ... Journal of medicinal chemistry 64 (24), 18158-18174, 2021 | 8 | 2021 |
| Novel approaches to glycomimetic design: development of small molecular weight lectin antagonists VC Damalanka, AR Maddirala, JW Janetka Expert Opinion on Drug Discovery 16 (5), 513-536, 2021 | 8 | 2021 |
| HGF/c-Met pathway inhibition combined with chemotherapy increases cytotoxic T-cell infiltration and inhibits pancreatic tumour growth and metastasis AR Mekapogu, Z Xu, S Pothula, C Perera, T Pang, SMZ Hosen, ... Cancer Letters 568, 216286, 2023 | 2 | 2023 |
| Inhibition of autocrine HGF maturation overcomes cetuximab resistance in colorectal cancer VT Jones, R Graves-Deal, Z Cao, G Bogatcheva, MA Ramirez, ... Cellular and Molecular Life Sciences 81 (1), 1-18, 2024 | 1 | 2024 |
| Hepatocyte growth factor/c-met pathway inhibition combined chemotherapy improves tumor immunity and eliminates metastasis in pancreatic cancer AR Mekapogu, Z Xu, SP Pothula, C Perera, T Pang, S Hosen, ... PANCREAS 50 (7), 1082-1082, 2021 | 1 | 2021 |
| Compounds and Methods Treating Bacterial Infections V Kalas, J Janetka, S Hultgren, J Pinkner, A Maddirala, V Damalanka WO Patent PCT/US2018/059,877, 2019 | 1 | 2019 |
| Mechanism-Based Macrocyclic Inhibitors of Serine Proteases VC Damalanka, V Banas, P De Bona, MM Kashipathy, K Battaile, S Lovell, ... Journal of Medicinal Chemistry 67 (6), 4833-4854, 2024 | | 2024 |
