Laurent Verkoczy
Laurent Verkoczy
Professor, San Diego Biomedical Research Institute
Verified email at
Cited by
Cited by
Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance
L Verkoczy, M Diaz, TM Holl, YB Ouyang, H Bouton-Verville, SM Alam, ...
Proceedings of the National Academy of Sciences 107 (1), 181-186, 2010
Antibody polyspecificity and neutralization of HIV-1: a hypothesis
BF Haynes, MA Moody, L Verkoczy, G Kelsoe, SM Alam
Human antibodies 14 (3-4), 59-67, 2005
Decreased frequency of somatic hypermutation and impaired affinity maturation but intact germinal center formation in mice expressing antisense RNA to DNA polymerase ζ
M Diaz, LK Verkoczy, MF Flajnik, NR Klinman
The Journal of Immunology 167 (1), 327-335, 2001
Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodies
L Verkoczy, G Kelsoe, MA Moody, BF Haynes
Current opinion in immunology 23 (3), 383-390, 2011
Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection
L Verkoczy, B Duong, P Skog, D Aït-Azzouzene, K Puri, JL Vela, ...
The Journal of Immunology 178 (10), 6332-6341, 2007
Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH× VL knockin mice reveals multiple tolerance controls
L Verkoczy, Y Chen, H Bouton-Verville, J Zhang, M Diaz, J Hutchinson, ...
The Journal of Immunology 187 (7), 3785-3797, 2011
An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1
M Bonsignori, K Wiehe, SK Grimm, R Lynch, G Yang, DM Kozink, F Perrin, ...
The Journal of clinical investigation 124 (4), 1835-1843, 2014
A role for nuclear factor kappa B/rel transcription factors in the regulation of the recombinase activator genes
L Verkoczy, D Aït-Azzouzene, P Skog, A Märtensson, J Lang, B Duong, ...
Immunity 22 (4), 519-531, 2005
Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10
Y Chen, J Zhang, KK Hwang, H Bouton-Verville, SM Xia, A Newman, ...
The Journal of Immunology 191 (3), 1260-1275, 2013
Immune perturbations in HIV–1-infected individuals who make broadly reactive neutralizing antibodies
MA Moody, I Pedroza-Pacheco, NA Vandergrift, C Chui, KE Lloyd, ...
Science immunology 1 (1), aag0851, 2016
Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: selection against MPER-associated autoreactivity limits T-dependent responses
L Verkoczy, Y Chen, J Zhang, H Bouton-Verville, A Newman, B Lockwood, ...
The Journal of Immunology 191 (5), 2538-2550, 2013
Decreased Frequency and Highly Aberrant Spectrum of Ultraviolet-Induced Mutations in the hprt Gene of Mouse Fibroblasts Expressing Antisense RNA to DNA Polymerase ζ11Public …
M Diaz, NB Watson, G Turkington, LK Verkoczy, NR Klinman, ...
Molecular Cancer Research 1 (11), 836-847, 2003
Progress in HIV-1 vaccine development
BF Haynes, MA Moody, M Alam, M Bonsignori, L Verkoczy, G Ferrari, ...
Journal of Allergy and Clinical Immunology 134 (1), 3-10, 2014
An immunoglobulin Cκ-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system
D Ait-Azzouzene, L Verkoczy, J Peters, A Gavin, P Skog, JL Vela, ...
The Journal of experimental medicine 201 (5), 817-828, 2005
Initiation of immune tolerance–controlled HIV gp41 neutralizing B cell lineages
R Zhang, L Verkoczy, K Wiehe, SM Alam, NI Nicely, S Santra, T Bradley, ...
Science translational medicine 8 (336), 336ra62-336ra62, 2016
HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design
M Bonsignori, SM Alam, HX Liao, L Verkoczy, GD Tomaras, BF Haynes, ...
Trends in microbiology 20 (11), 532-539, 2012
The bryophyte Physcomitrella patens replicates extrachromosomal transgenic elements
NW Ashton, CEM Champagne, T Weiler, LK Verkoczy
New Phytologist 146 (3), 391-402, 2000
Host controls of HIV neutralizing antibodies
BF Haynes, L Verkoczy
Science 344 (6184), 588-589, 2014
Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation
SM Alam, HX Liao, SM Dennison, F Jaeger, R Parks, K Anasti, A Foulger, ...
Journal of virology 85 (22), 11725-11731, 2011
Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution
X Shen, SM Dennison, P Liu, F Gao, F Jaeger, DC Montefiori, L Verkoczy, ...
Proceedings of the National Academy of Sciences 107 (13), 5972-5977, 2010
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