Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases L Minghetti Journal of Neuropathology & Experimental Neurology 63 (9), 901-910, 2004 | 836 | 2004 |
Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide L Minghetti, G Levi Progress in neurobiology 54 (1), 99-125, 1998 | 719 | 1998 |
Role of inflammation in neurodegenerative diseases L Minghetti Current opinion in neurology 18 (3), 315-321, 2005 | 457 | 2005 |
Activation of α7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures R De Simone, MA Ajmone-Cat, D Carnevale, L Minghetti Journal of neuroinflammation 2 (1), 1-10, 2005 | 291 | 2005 |
Role of the peroxisome proliferator‐activated receptor‐γ (PPAR‐γ) and its natural ligand 15‐deoxy‐Δ12,14‐prostaglandin J2 in the regulation of microglial functions A Bernardo, G Levi, L Minghetti European Journal of Neuroscience 12 (7), 2215-2223, 2000 | 287 | 2000 |
In vitro neuronal and glial differentiation from embryonic or adult neural precursor cells are differently affected by chronic or acute activation of microglia E Cacci, MA Ajmone‐Cat, T Anelli, S Biagioni, L Minghetti Glia 56 (4), 412-425, 2008 | 253 | 2008 |
PPAR-γ agonists as regulators of microglial activation and brain inflammation A Bernardo, L Minghetti Current pharmaceutical design 12 (1), 93-109, 2006 | 227 | 2006 |
Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation L Minghetti, MA Ajmone-Cat, MA De Berardinis, R De Simone Brain research reviews 48 (2), 251-256, 2005 | 199 | 2005 |
Induction of prostanoid biosynthesis by bacterial lipopolysaccharide and isoproterenol in rat microglial cultures L Minghetti, G Levi Journal of neurochemistry 65 (6), 2690-2698, 1995 | 197 | 1995 |
Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors L Minghetti, A Nicolini, E Polazzi, C CRéminon, J Maclouf, G Levi Glia 19 (2), 152-160, 1997 | 183 | 1997 |
Regulation of prostanoid synthesis in microglial cells and effects of prostaglandin E2 on microglial functions G Levi, L Minghetti, F Aloisi Biochimie 80 (11), 899-904, 1998 | 166 | 1998 |
Microglia-neuron interaction in inflammatory and degenerative diseases: role of cholinergic and noradrenergic systems L Minghetti, D Carnevale, RD Simone CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2007 | 164 | 2007 |
Isoprostanes, novel markers of oxidative injury, help understanding the pathogenesis of neurodegenerative diseases A Greco, L Minghetti, G Levi Neurochemical research 25, 1357-1364, 2000 | 149 | 2000 |
Purification of multiple forms of glial growth factor. AD Goodearl, JB Davis, K Mistry, L Minghetti, M Otsu, MD Waterfield, ... Journal of Biological Chemistry 268 (24), 18095-18102, 1993 | 146 | 1993 |
Regulation of glial cell functions by PPAR-γ natural and synthetic agonists A Bernardo, L Minghetti PPAR research 2008, 2008 | 131 | 2008 |
Interferon‐γ and nitric oxide down‐regulate lipopolysaccharide‐induced prostanoid production in cultured rat microglial cells by inhibiting cyclooxygenase‐2 expression L Minghetti, E Polazzi, A Nicolini, C Créminon, G Levi Journal of neurochemistry 66 (5), 1963-1970, 1996 | 130 | 1996 |
Non-steroidal anti-inflammatory drugs and brain inflammation: effects on microglial functions MA Ajmone-Cat, A Bernardo, A Greco, L Minghetti Pharmaceuticals 3 (6), 1949-1965, 2010 | 125 | 2010 |
Cyclo‐oxygenase‐1 and ‐2 differently contribute to prostaglandin E2 synthesis and lipid peroxidation after in vivo activation of N‐methyl‐d‐aspartate receptors … O Pepicelli, E Fedele, M Berardi, M Raiteri, G Levi, A Greco, ... Journal of neurochemistry 93 (6), 1561-1567, 2005 | 125 | 2005 |
Functional characterization of substance P receptors on cultured human spinal cord astrocytes: synergism of substance P with cytokines in inducing interleukin‐6 and … C Palma, L Minghetti, M Astolfi, E Ambrosini, F Ceccherini Silberstein, ... Glia 21 (2), 183-193, 1997 | 125 | 1997 |
Up‐regulation of Cyclooxygenase‐2 Expression in Cultured Microglia by Prostaglandin E2, Cyclic AMP and Non‐steroidal Anti‐inflammatory Drugs L Minghetti, E Polazzi, A Nicolini, C Créminon, G Levi European Journal of Neuroscience 9 (5), 934-940, 1997 | 125 | 1997 |