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Rachel D. Melamed
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Year
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum
SC Bendall, EF Simonds, P Qiu, ED Amir, PO Krutzik, R Finck, ...
Science 332 (6030), 687-696, 2011
23992011
Foxp3 transcription-factor-dependent and-independent regulation of the regulatory T cell transcriptional signature
JA Hill, M Feuerer, K Tash, S Haxhinasto, J Perez, R Melamed, D Mathis, ...
Immunity 27 (5), 786-800, 2007
7622007
A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk
DR Blair, CS Lyttle, JM Mortensen, CF Bearden, AB Jensen, ...
Cell 155 (1), 70-80, 2013
2472013
Sustained antigen presentation can promote an immunogenic T cell response, like dendritic cell activation
R Obst, HM van Santen, R Melamed, AO Kamphorst, C Benoist, D Mathis
Proceedings of the National Academy of Sciences 104 (39), 15460-15465, 2007
1002007
FBXW7 Mutations in Melanoma and a New Therapeutic Paradigm
IT Aydin, RD Melamed, SJ Adams, M Castillo-Martin, A Demir, D Bryk, ...
Journal of the National Cancer Institute 106 (6), dju107, 2014
932014
Gene expression microarrays: glimpses of the immunological genome
G Hyatt, R Melamed, R Park, R Seguritan, C Laplace, L Poirot, S Zucchelli, ...
Nature immunology 7 (7), 686-691, 2006
872006
Genomic characterization of dysplastic nevi unveils implications for diagnosis of melanoma
RD Melamed, IT Aydin, GS Rajan, R Phelps, DN Silvers, KJ Emmett, ...
Journal of Investigative Dermatology 137 (4), 905-909, 2017
632017
The variable immunological self: genetic variation and nongenetic noise in Aire-regulated transcription
ES Venanzi, R Melamed, D Mathis, C Benoist
Proceedings of the National Academy of Sciences 105 (41), 15860-15865, 2008
592008
Genetic similarity between cancers and comorbid Mendelian diseases identifies candidate driver genes
RD Melamed, KJ Emmett, C Madubata, A Rzhetsky, R Rabadan
Nature communications 6 (1), 7033, 2015
432015
Data-driven discovery of seasonally linked diseases from an Electronic Health Records system
RD Melamed, H Khiabanian, R Rabadan
BMC bioinformatics 15, 1-10, 2014
382014
GAB2 induces tumor angiogenesis in NRAS-driven melanoma
Y Yang, J Wu, A Demir, M Castillo-Martin, RD Melamed, G Zhang, ...
Oncogene 32 (31), 3627-3637, 2013
312013
An information theoretic method to identify combinations of genomic alterations that promote glioblastoma
RD Melamed, J Wang, A Iavarone, R Rabadan
Journal of molecular cell biology 7 (3), 203-213, 2015
162015
Patchwork of contrasting medication cultures across the USA
RD Melamed, A Rzhetsky
Nature Communications 9 (1), 1-12, 2018
52018
Using indication embeddings to represent patient health for drug safety studies
RD Melamed
JAMIA open 3 (3), 422-430, 2020
42020
Effects of Antidepressants on COVID-19 Outcomes: Retrospective Study on Large-Scale Electronic Health Record Data
MM Rahman, AM Mahi, R Melamed, MAU Alam
Interactive Journal of Medical Research 12 (1), e39455, 2023
12023
Mapping drug biology to disease genetics to discover drug impacts on the human phenome
M Habib, PN Lalagkas, RD Melamed
bioRxiv, 2023.01. 22.525094, 2023
2023
Mendelian disease comorbidity as a resource for novel therapeutic targets
PN Lalakgas, RD Melamed
bioRxiv, 2023.07. 23.550190, 2023
2023
Drug-combination wide association studies of cancer
PN Lalagkas, RD Melamed
medRxiv, 2022.09. 29.22280479, 2022
2022
Mining patterns in genomic and clinical cancer data to characterize novel driver genes
RD Melamed
Columbia University, 2015
2015
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Articles 1–19