| Discovery of ledipasvir (GS-5885): a potent, once-daily oral NS5A inhibitor for the treatment of hepatitis C virus infection JO Link, JG Taylor, L Xu, M Mitchell, H Guo, H Liu, D Kato, T Kirschberg, ... Journal of medicinal chemistry 57 (5), 2033-2046, 2014 | 314 | 2014 |
| Perspectives on alkyl carbonates in organic synthesis JP Parrish, RN Salvatore, KW Jung Tetrahedron 56 (42), 8207-8238, 2000 | 215 | 2000 |
| Antiviral compounds H Guo, D Kato, TA Kirschberg, H Liu, JO Link, ML Mitchell, JP Parrish, ... US Patent 8,088,368, 2012 | 142 | 2012 |
| Antiviral compounds H Guo, D Kato, TA Kirschberg, H Liu, JO Link, ML Mitchell, JP Parrish, ... US Patent 8,088,368, 2012 | 134 | 2012 |
| Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study RL Mackman, M Sangi, D Sperandio, JP Parrish, E Eisenberg, M Perron, ... Journal of Medicinal Chemistry 58 (4), 1630-1643, 2015 | 129 | 2015 |
| 1′-substituted carba-nucleoside analogs for antiviral treatment T Butler, A Cho, CU Kim, J Parrish, OL Saunders, L Zhang US Patent 8,008,264, 2011 | 117 | 2011 |
| Oxidative dimerization: Pd (II) catalysis in the presence of oxygen using aqueous media JP Parrish, YC Jung, RJ Floyd, KW Jung Tetrahedron letters 43 (44), 7899-7902, 2002 | 113 | 2002 |
| Carba-nucleoside analogs for antiviral treatment A Cho, CU Kim, J Parrish, J Xu US Patent 8,012,941, 2011 | 111 | 2011 |
| Mild and Efficient Aryl− Alkenyl Coupling via Pd (II) Catalysis in the Presence of Oxygen or Cu (II) Oxidants JP Parrish, YC Jung, SI Shin, KW Jung The Journal of Organic Chemistry 67 (20), 7127-7130, 2002 | 110 | 2002 |
| 1′ substituted carba-nucleoside analogs for antiviral treatment T Butler, A Cho, CU Kim, JP Parrish, OL Saunders, L Zhang US Patent 8,318,682, 2012 | 99 | 2012 |
| DNA alkylation properties of yatakemycin JP Parrish, DB Kastrinsky, SE Wolkenberg, Y Igarashi, DL Boger Journal of the American Chemical Society 125 (36), 10971-10976, 2003 | 90 | 2003 |
| Sensor fusion system architecture D Skrbina, ST Kronen US Patent 6,862,537, 2005 | 85* | 2005 |
| Methods for treating Filoviridae virus infections BK Chun, MONH Clarke, E Doerffler, HC Hui, R Jordan, RL Mackman, ... US Patent 9,724,360, 2017 | 70 | 2017 |
| 1′-substituted carba-nucleoside analogs for antiviral treatment T Butler, A Cho, CU Kim, JP Parrish, OL Saunders, L Zhang US Patent 8,853,171, 2014 | 69* | 2014 |
| Design, synthesis, and anti-HIV activity of 4′-modified carbocyclic nucleoside phosphonate reverse transcriptase inhibitors CG Boojamra, JP Parrish, D Sperandio, Y Gao, OV Petrakovsky, SK Lee, ... Bioorganic & Medicinal Chemistry 17 (4), 1739-1746, 2009 | 67 | 2009 |
| Nucleoside analogs for antiviral treatment JM Chen, AX Huang, RL Mackman, J Parrish, JK Perry, OL Saunders, ... US Patent 8,324,179, 2012 | 64 | 2012 |
| Establishment of substituent effects in the DNA binding subunit of CBI analogues of the duocarmycins and CC-1065 JP Parrish, DB Kastrinsky, F Stauffer, MP Hedrick, I Hwang, DL Boger Bioorganic & medicinal chemistry 11 (17), 3815-3838, 2003 | 62 | 2003 |
| A human single-chain antibody specific for integrin α3β1 capable of cell internalization and delivery of antitumor agents AM Lillo, C Sun, C Gao, H Ditzel, J Parrish, CM Gauss, J Moss, ... Chemistry & Biology 11 (7), 897-906, 2004 | 51 | 2004 |
| Establishing the parabolic relationship between reactivity and activity for derivatives and analogues of the duocarmycin and CC-1065 alkylation subunits JP Parrish, TV Hughes, I Hwang, DL Boger Journal of the American Chemical Society 126 (1), 80-81, 2004 | 48 | 2004 |
| Synthesis and characterization of 2′-C-Me branched C-nucleosides as HCV polymerase inhibitors A Cho, L Zhang, J Xu, D Babusis, T Butler, R Lee, OL Saunders, T Wang, ... Bioorganic & medicinal chemistry letters 22 (12), 4127-4132, 2012 | 45 | 2012 |
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