Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study J Geisler, B Haynes, G Anker, M Dowsett, PE Lønning Journal of Clinical Oncology 20 (3), 751-757, 2002 | 707 | 2002 |
Pharmacology of novel steroidal inhibitors of cytochrome P45017α (17α-hydroxylase/C17–20 lyase) SE Barrie, GA Potter, PM Goddard, BP Haynes, M Dowsett, M Jarman The Journal of steroid biochemistry and molecular biology 50 (5-6), 267-273, 1994 | 312 | 1994 |
CYP2D6 and UGT2B7 Genotype and Risk of Recurrence in Tamoxifen-Treated Breast Cancer Patients JM Rae, S Drury, DF Hayes, V Stearns, JN Thibert, BP Haynes, J Salter, ... Journal of the National Cancer Institute 104 (6), 452-460, 2012 | 303 | 2012 |
The pharmacology of letrozole BP Haynes, M Dowsett, WR Miller, JM Dixon, AS Bhatnagar The Journal of steroid biochemistry and molecular biology 87 (1), 35-45, 2003 | 195 | 2003 |
The relationship between inhibition of vitamin K1 2, 3‐epoxide reductase and reduction of clotting factor activity with warfarin. IA Choonara, RG Malia, BP Haynes, CR Hay, S Cholerton, ... British journal of clinical pharmacology 25 (1), 1-7, 1988 | 150 | 1988 |
Acquired tamoxifen resistance in human breast cancer and reduced intra-tumoral drug concentration SRD Johnston, M Dowsett, IE Smith, NPM Sacks, BP Haynes, M Jarman, ... The Lancet 342 (8886-8887), 1521-1522, 1993 | 126 | 1993 |
Idoxifene: report of a phase I study in patients with metastatic breast cancer RC Coombes, BP Haynes, M Dowsett, M Quigley, J English, IR Judson, ... Cancer Research 55 (5), 1070-1074, 1995 | 123 | 1995 |
Intratumoral estrogen disposition in breast cancer BP Haynes, AH Straume, J Geisler, R A'Hern, H Helle, IE Smith, ... Clinical Cancer Research 16 (6), 1790-1801, 2010 | 115 | 2010 |
Stereoselective interaction between the R enantiomer of warfarin and cimetidine. IA Choonara, S Cholerton, BP Haynes, AM Breckenridge, BK Park British journal of clinical pharmacology 21 (3), 271-277, 1986 | 104 | 1986 |
Hormonal effects of aromatase inhibitors: focus on premenopausal effects and interaction with tamoxifen M Dowsett, BP Haynes The Journal of steroid biochemistry and molecular biology 86 (3-5), 255-263, 2003 | 102 | 2003 |
Plasma disposition of vitamin K1 in relation to anticoagulant poisoning. BK Park, AK Scott, AC Wilson, BP Haynes, AM Breckenridge British journal of clinical pharmacology 18 (5), 655-662, 1984 | 98 | 1984 |
The influence of CGS 16949A on peripheral aromatisation in breast cancer patients PE Lønning, S Jacobs, A Jones, B Haynes, T Powles, M Dowsett British journal of cancer 63 (5), 789-793, 1991 | 92 | 1991 |
Enantiomers of warfarin and vitamin K1 metabolism. IA Choonara, BP Haynes, S Cholerton, AM Breckenridge, BK Park British journal of clinical pharmacology 22 (6), 729-732, 1986 | 90 | 1986 |
Idoxifene antagonizes estradiol-dependent MCF-7 breast cancer xenograft growth through sustained induction of apoptosis SRD Johnston, IM Boeddinghaus, S Riddler, BP Haynes, IR Hardcastle, ... Cancer research 59 (15), 3646-3651, 1999 | 73 | 1999 |
3- and 4-Pyridylalkyl Adamantanecarboxylates: Inhibitors of Human Cytochrome P45017α (17α-Hydroxylase/C17,20-Lyase). Potential Nonsteroidal Agents for … FCY Chan, GA Potter, SE Barrie, BP Haynes, MG Rowlands, J Houghton, ... Journal of medicinal chemistry 39 (17), 3319-3323, 1996 | 69 | 1996 |
Total body aromatization in postmenopausal breast cancer patients is strongly correlated to plasma leptin levels J Geisler, B Haynes, D Ekse, M Dowsett, PE Lønning The Journal of steroid biochemistry and molecular biology 104 (1-2), 27-34, 2007 | 68 | 2007 |
Exploring breast cancer estrogen disposition: the basis for endocrine manipulation PE Lønning, BP Haynes, AH Straume, A Dunbier, H Helle, S Knappskog, ... Clinical Cancer Research 17 (15), 4948-4958, 2011 | 67 | 2011 |
The biology of steroid hormones and endocrine treatment of breast cancer M Dowsett, E Folkerd, D Doody, B Haynes The breast 14 (6), 452-457, 2005 | 66 | 2005 |
Abstract S1-7: Lack of Correlation between Gene Variants in Tamoxifen Metabolizing Enymes with Primary Endpoints in the ATAC Trial. JM Rae, S Drury, DF Hayes, V Stearns, JN Thibert, BP Haynes, J Salter, ... Cancer Research 70 (24_Supplement), S1-7-S1-7, 2010 | 65 | 2010 |
Biochemistry and pharmacokinetics of potent non-steroidal cytochrome P45017α inhibitors SE Barrie, BP Haynes, GA Potter, FCY Chan, PM Goddard, M Dowsett, ... The Journal of steroid biochemistry and molecular biology 60 (5-6), 347-351, 1997 | 58 | 1997 |