Delivery of siRNA to the brain using a combination of nose-to-brain delivery and cell-penetrating peptide-modified nano-micelles T Kanazawa, F Akiyama, S Kakizaki, Y Takashima, Y Seta Biomaterials 34 (36), 9220-9226, 2013 | 229 | 2013 |
Cell-penetrating peptide-modified block copolymer micelles promote direct brain delivery via intranasal administration T Kanazawa, H Taki, K Tanaka, Y Takashima, H Okada Pharmaceutical research 28, 2130-2139, 2011 | 164 | 2011 |
Prolongation of life in rats with malignant glioma by intranasal siRNA/drug codelivery to the brain with cell-penetrating peptide-modified micelles T Kanazawa, K Morisaki, S Suzuki, Y Takashima Molecular pharmaceutics 11 (5), 1471-1478, 2014 | 141 | 2014 |
Spray-drying preparation of microparticles containing cationic PLGA nanospheres as gene carriers for avoiding aggregation of nanospheres Y Takashima, R Saito, A Nakajima, M Oda, A Kimura, T Kanazawa, ... International journal of pharmaceutics 343 (1-2), 262-269, 2007 | 110 | 2007 |
Topical drug delivery to retinal pigment epithelium with microfluidizer produced small liposomes T Lajunen, K Hisazumi, T Kanazawa, H Okada, Y Seta, M Yliperttula, ... European Journal of Pharmaceutical Sciences 62, 23-32, 2014 | 106 | 2014 |
Disulfide crosslinked stearoyl carrier peptides containing arginine and histidine enhance siRNA uptake and gene silencing K Tanaka, T Kanazawa, T Ogawa, Y Takashima, T Fukuda, H Okada International journal of pharmaceutics 398 (1-2), 219-224, 2010 | 87 | 2010 |
Development of an efficient transdermal delivery system of small interfering RNA using functional peptides, Tat and AT-1002 T Uchida, T Kanazawa, Y Takashima, H Okada Chemical and Pharmaceutical Bulletin 59 (2), 196-201, 2011 | 86 | 2011 |
Suppression of tumor growth by systemic delivery of anti-VEGF siRNA with cell-penetrating peptide-modified MPEG–PCL nanomicelles T Kanazawa, K Sugawara, K Tanaka, S Horiuchi, Y Takashima, H Okada European journal of pharmaceutics and biopharmaceutics 81 (3), 470-477, 2012 | 77 | 2012 |
Development of cell-penetrating peptide-modified MPEG-PCL diblock copolymeric nanoparticles for systemic gene delivery K Tanaka, T Kanazawa, Y Shibata, Y Suda, T Fukuda, Y Takashima, ... International journal of pharmaceutics 396 (1-2), 229-238, 2010 | 73 | 2010 |
Sustained-release of protein from biodegradable sericin film, gel and sponge A Nishida, M Yamada, T Kanazawa, Y Takashima, K Ouchi, H Okada International journal of pharmaceutics 407 (1-2), 44-52, 2011 | 72 | 2011 |
Therapeutic effects on atopic dermatitis by anti-RelA short interfering RNA combined with functional peptides Tat and AT1002 T Uchida, T Kanazawa, M Kawai, Y Takashima, H Okada Journal of Pharmacology and Experimental Therapeutics 338 (2), 443-450, 2011 | 71 | 2011 |
Intranasal delivery of camptothecin-loaded tat-modified nanomicells for treatment of intracranial brain tumors H Taki, T Kanazawa, F Akiyama, Y Takashima, H Okada Pharmaceuticals 5 (10), 1092-1102, 2012 | 68 | 2012 |
Nose-to-brain drug delivery system with ligand/cell-penetrating peptide-modified polymeric nano-micelles for intracerebral gliomas T Kanazawa, H Taki, H Okada European Journal of Pharmaceutics and Biopharmaceutics 152, 85-94, 2020 | 59 | 2020 |
Enhancement of nose-to-brain delivery of hydrophilic macromolecules with stearate-or polyethylene glycol-modified arginine-rich peptide T Kanazawa, M Kaneko, T Niide, F Akiyama, S Kakizaki, H Ibaraki, ... International Journal of Pharmaceutics 530 (1-2), 195-200, 2017 | 58 | 2017 |
Cytoplasm-responsive nanocarriers conjugated with a functional cell-penetrating peptide for systemic siRNA delivery K Tanaka, T Kanazawa, S Horiuchi, T Ando, K Sugawara, Y Takashima, ... International journal of pharmaceutics 455 (1-2), 40-47, 2013 | 57 | 2013 |
Brain delivery of small interfering ribonucleic acid and drugs through intranasal administration with nano-sized polymer micelles T Kanazawa Medical Devices: Evidence and Research, 57-64, 2015 | 47 | 2015 |
Therapeutic effects in a transient middle cerebral artery occlusion rat model by nose-to-brain delivery of anti-TNF-alpha siRNA with cell-penetrating peptide-modified polymer … T Kanazawa, T Kurano, H Ibaraki, Y Takashima, T Suzuki, Y Seta Pharmaceutics 11 (9), 478, 2019 | 39 | 2019 |
Effects of menstrual cycle on gene transfection through mouse vagina for DNA vaccine T Kanazawa, Y Takashima, S Hirayama, H Okada International journal of pharmaceutics 360 (1-2), 164-170, 2008 | 39 | 2008 |
Effects of surface charge and flexibility of liposomes on dermal drug delivery H Ibaraki, T Kanazawa, C Oogi, Y Takashima, Y Seta Journal of drug delivery science and technology 50, 155-162, 2019 | 38 | 2019 |
A novel, bio-reducible gene vector containing arginine and histidine enhances gene transfection and expression of plasmid DNA K Tanaka, T Kanazawa, T Ogawa, Y Suda, Y Takashima, T Fukuda, ... Chemical and Pharmaceutical Bulletin 59 (2), 202-207, 2011 | 38 | 2011 |