Lubor Borsig
Lubor Borsig
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Molecular basis of metastasis
AC Chiang, J Massagué
New England Journal of Medicine 359 (26), 2814-2823, 2008
Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis
L Borsig, R Wong, J Feramisco, DR Nadeau, NM Varki, A Varki
Proceedings of the National Academy of Sciences 98 (6), 3352-3357, 2001
P-selectin deficiency attenuates tumor growth and metastasis
YJ Kim, L Borsig, NM Varki, A Varki
Proceedings of the National Academy of Sciences 95 (16), 9325-9330, 1998
Synergistic effects of L-and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis
L Borsig, R Wong, RO Hynes, NM Varki, A Varki
Proceedings of the National Academy of Sciences 99 (4), 2193-2198, 2002
Cancer cell adhesion and metastasis: selectins, integrins, and the inhibitory potential of heparins
G Bendas, L Borsig
International journal of cell biology 2012, 2012
Selectins promote tumor metastasis
H Läubli, L Borsig
Seminars in cancer biology 20 (3), 169-177, 2010
Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas
M Wahrenbrock, L Borsig, D Le, N Varki, A Varki
The Journal of clinical investigation 112 (6), 853-862, 2003
Altered tumor-cell glycosylation promotes metastasis
I Häuselmann, L Borsig
Frontiers in oncology 4, 28, 2014
P-selectin mediates the adhesion of sickle erythrocytes to the endothelium
NM Matsui, L Borsig, SD Rosen, M Yaghmai, A Varki, SH Embury
Blood 98 (6), 1955-1962, 2001
Distinct selectin ligands on colon carcinoma mucins can mediate pathological interactions among platelets, leukocytes, and endothelium
YJ Kim, L Borsig, HL Han, NM Varki, A Varki
The American journal of pathology 155 (2), 461-472, 1999
Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway
MJ Wolf, A Hoos, J Bauer, S Boettcher, M Knust, A Weber, N Simonavicius, ...
Cancer cell 22 (1), 91-105, 2012
The role of platelet activation in tumor metastasis
L Borsig
Expert review of anticancer therapy 8 (8), 1247-1255, 2008
Selectin blocking activity of a fucosylated chondroitin sulfate glycosaminoglycan from sea cucumber effect on tumor metastasis and neutrophil recruitment
L Borsig, L Wang, MCM Cavalcante, L Cardilo-Reis, PL Ferreira, ...
Journal of Biological Chemistry 282 (20), 14984-14991, 2007
L-selectin facilitation of metastasis involves temporal induction of Fut7-dependent ligands at sites of tumor cell arrest
H Läubli, JL Stevenson, A Varki, NM Varki, L Borsig
Cancer research 66 (3), 1536-1542, 2006
Inflammatory chemokines and metastasis—tracing the accessory
L Borsig, MJ Wolf, M Roblek, A Lorentzen, M Heikenwalder
Oncogene 33 (25), 3217-3224, 2014
Heparin attenuates metastasis mainly due to inhibition of P-and L-selectin, but non-anticoagulant heparins can have additional effects
JL Stevenson, A Varki, L Borsig
Thrombosis Research 120, S107-S111, 2007
Tumor attenuation by combined heparan sulfate and polyamine depletion
M Belting, L Borsig, MM Fuster, JR Brown, L Persson, LÅ Fransson, ...
Proceedings of the National Academy of Sciences 99 (1), 371-376, 2002
P‐selectin‐and heparanase‐dependent antimetastatic activity of non‐anticoagulant heparins
N Hostettler, A Naggi, G Torri, R Ishai‐Michaeli, B Casu, I Vlodavsky, ...
The FASEB Journal 21 (13), 3562-3572, 2007
Increased primary tumor growth in mice null for β3-or β3/β5-integrins or selectins
D Taverna, H Moher, D Crowley, L Borsig, A Varki, RO Hynes
Proceedings of the National Academy of Sciences 101 (3), 763-768, 2004
Selectin-mediated activation of endothelial cells induces expression of CCL5 and promotes metastasis through recruitment of monocytes
H Läubli, KS Spanaus, L Borsig
Blood, The Journal of the American Society of Hematology 114 (20), 4583-4591, 2009
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