Transient PLK4 overexpression accelerates tumorigenesis in p53-deficient epidermis Ö Serçin, JC Larsimont, AE Karambelas, V Marthiens, V Moers, B Boeckx, ... Nature cell biology 18 (1), 100-110, 2016 | 177 | 2016 |
Reconstitution of human claspin-mediated phosphorylation of Chk1 by the ATR (ataxia telangiectasia-mutated and rad3-related) checkpoint kinase LA Lindsey-Boltz, Ö Serçin, JH Choi, A Sancar Journal of biological chemistry 284 (48), 33107-33114, 2009 | 56 | 2009 |
A scalable CRISPR/Cas9-based fluorescent reporter assay to study DNA double-strand break repair choice P Roidos, S Sungalee, S Benfatto, Ö Serçin, AM Stütz, A Abdollahi, ... Nature Communications 11 (1), 4077, 2020 | 39 | 2020 |
Characterization of functional domains in human Claspin Ö Serçin, MG Kemp Cell Cycle 10 (10), 1599-1606, 2011 | 34 | 2011 |
Genome-wide screens implicate loss of cullin ring ligase 3 in persistent proliferation and genome instability in TP53-deficient cells AP Drainas, RA Lambuta, I Ivanova, Ö Serçin, I Sarropoulos, ML Smith, ... Cell Reports 31 (1), 2020 | 23 | 2020 |
Uncovering cancer vulnerabilities by machine learning prediction of synthetic lethality S Benfatto, Ö Serçin, FR Dejure, A Abdollahi, FT Zenke, BR Mardin Molecular Cancer 20 (1), 111, 2021 | 14 | 2021 |
A solid‐phase transfection platform for arrayed CRISPR screens Ö Serçin, S Reither, P Roidos, N Ballin, S Palikyras, A Baginska, K Rein, ... Molecular systems biology 15 (12), e8983, 2019 | 10 | 2019 |
High‐resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD U Schwartz, M Llamazares Prada, ST Pohl, M Richter, R Tamas, ... The EMBO Journal 42 (12), e111272, 2023 | 3 | 2023 |
High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD phenotypes in human lung fibroblasts U Schwartz, ML Prada, ST Pohl, M Richter, R Tamas, M Schuler, C Keller, ... bioRxiv, 2022.03. 28.486023, 2022 | 1 | 2022 |
The interplay of DNA repair context with target sequence predictably biasses Cas9-generated mutations A Pallaseni, EM Peets, G Girling, L Crepaldi, I Kuzmin, U Raudvere, ... bioRxiv, 2023 | | 2023 |
A solid‐phase transfection platform for arrayed CRISPR screens Ö Serçin, S Reither, P Roidos, N Ballin, S Palikyras, A Baginska, K Rein, ... Molecular Systems Biology 16 (6), e9611, 2020 | | 2020 |
Interactions of Claspin with replication and checkpoint proteins O Sercin University of North Carolina at Chapel Hill, 2011 | | 2011 |
RECONSTITUTION OF HUMAN CLASPIN-MEDIATED PHOSPHORYLATION OF CHK1 BY THE ATR CHECKPOINT KINASE LA Lindsey-Boltz, Ö Serçin, JH Choi, A Sancar | | 2009 |