Tokiharu Takahashi
Tokiharu Takahashi
Professor and Chair, Tokyo Medical University
Verified email at - Homepage
Cited by
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Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells
K Kumano, S Chiba, A Kunisato, M Sata, T Saito, E Nakagami-Yamaguchi, ...
Immunity 18 (5), 699-711, 2003
The oncoprotein Evi-1 represses TGF-β signalling by inhibiting Smad3
M Kurokawa, K Mitani, K Irie, T Matsuyama, T Takahashi, S Chiba, ...
Nature 394 (6688), 92-96, 1998
Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone
T Yamauchi, K Ueki, K Tobe, H Tamemoto, N Sekine, M Wada, M Honjo, ...
Nature 390 (6655), 91-96, 1997
Mouse jagged1 physically interacts with notch2 and other notch receptors: assessment by quantitative methods
K Shimizu, S Chiba, K Kumano, N Hosoya, T Takahashi, Y Kanda, ...
Journal of Biological Chemistry 274 (46), 32961-32969, 1999
Amphioxus functional genomics and the origins of vertebrate gene regulation
F Marlétaz, PN Firbas, I Maeso, JJ Tena, O Bogdanovic, M Perry, ...
Nature 564 (7734), 64-70, 2018
Homozygous loss of the cyclin-dependent kinase 4-inhibitor (p16) gene in human leukemias
S Ogawa, N Hirano, N Sato, T Takahashi, A Hangaishi, K Tanaka, ...
Suppression of arthritic bone destruction by adenovirus-mediated csk gene transfer to synoviocytes and osteoclasts
H Takayanagi, T Juji, T Miyazaki, H Iizuka, T Takahashi, M Isshiki, ...
The Journal of clinical investigation 104 (2), 137-146, 1999
Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression
K Kumano, S Chiba, K Shimizu, T Yamagata, N Hosoya, T Saito, ...
Blood, The Journal of the American Society of Hematology 98 (12), 3283-3289, 2001
Expression of costimulatory molecules in human leukemias.
N Hirano, T Takahashi, S Ohtake, K Hirashima, N Emi, K Saito, M Hirano, ...
Leukemia 10 (7), 1168-1176, 1996
Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulation
K Shimizu, S Chiba, T Saito, K Kumano, T Takahashi, H Hirai
Journal of Biological Chemistry 276 (28), 25753-25758, 2001
The evi‐1 oncoprotein inhibits c‐Jun N‐terminal kinase and prevents stress‐induced cell death
M Kurokawa, K Mitani, T Yamagata, T Takahashi, K Izutsu, S Ogawa, ...
The EMBO journal, 2000
Expression of Notch ligands, Jagged1, 2 and Delta1 in antigen presenting cells in mice
E Yamaguchi, S Chiba, K Kumano, A Kunisato, T Takahashi, T Takahashi, ...
Immunology letters 81 (1), 59-64, 2002
The evolution of homeobox genes: Implications for the study of brain development
PWH Holland, T Takahashi
Brain research bulletin 66 (4-6), 484-490, 2005
Comparative genomic and phylogenetic analysis of vitellogenin and other large lipid transfer proteins in metazoans
A Hayward, T Takahashi, WG Bendena, SS Tobe, JHL Hui
FEBS letters 584 (6), 1273-1278, 2010
Amphioxus and ascidian Dmbx homeobox genes give clues to the vertebrate origins of midbrain development
T Takahashi, PWH Holland
Oxford University Press for The Company of Biologists Limited 131 (14), 3285 …, 2004
Growth hormone-induced tyrosine phosphorylation of EGF receptor as an essential element leading to MAP kinase activation and gene expression
T Yamauchi, K Ueki, K Tobe, H Tamemoto, N Sekine, M Wada, M Honjo, ...
Endocrine journal 45 (Suppl), S27-S31, 1998
Defective neural crest migration revealed by a Zebrafish model of Alx1-related frontonasal dysplasia
CT Dee, CR Szymoniuk, PED Mills, T Takahashi
Human molecular genetics 22 (2), 239-251, 2013
Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain
K Shimizu, S Chiba, T Saito, T Takahashi, K Kumano, Y Hamada, H Hirai
The EMBO Journal, 2002
Evolution and functional divergence of enzymes involved in sesquiterpenoid hormone biosynthesis in crustaceans and insects
JHL Hui, A Hayward, WG Bendena, T Takahashi, SS Tobe
Peptides 31 (3), 451-455, 2010
Modulation of osteoclast function by adenovirus vector‐induced epidermal growth factor receptor
S Tanaka, T Takahashi, H Takayanagi, T Miyazaki, H Oda, K Nakamura, ...
Journal of Bone and Mineral Research 13 (11), 1714-1720, 1998
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