| Genetic clonal diversity predicts progression to esophageal adenocarcinoma CC Maley, PC Galipeau, JC Finley, VJ Wongsurawat, X Li, CA Sanchez, ... Nature genetics 38 (4), 468-473, 2006 | 805 | 2006 |
| Telomere-to-telomere assembly of a complete human X chromosome KH Miga, S Koren, A Rhie, MR Vollger, A Gershman, A Bzikadze, ... Nature 585 (7823), 79-84, 2020 | 679 | 2020 |
| Detecting ultralow-frequency mutations by Duplex Sequencing SR Kennedy, MW Schmitt, EJ Fox, BF Kohrn, JJ Salk, EH Ahn, MJ Prindle, ... Nature protocols 9 (11), 2586, 2014 | 527 | 2014 |
| Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers J Rodriguez, J Frigola, E Vendrell, RA Risques, MF Fraga, C Morales, ... Cancer research 66 (17), 8462-9468, 2006 | 426 | 2006 |
| Promoter hypermethylation of the DNA repair gene O6-methylguanine-DNA methyltransferase is associated with the presence of G: C to A: T transition mutations in p53 in human … M Esteller, RA Risques, M Toyota, G Capella, V Moreno, MA Peinado, ... Cancer research 61 (12), 4689-4692, 2001 | 424 | 2001 |
| K-ras and p16 Aberrations Confer Poor Prognosis in Human Colorectal Cancer M Esteller, S Gonzalez, RA Risques, E Marcuello, R Mangues, JR Germa, ... Journal of Clinical Oncology 19 (2), 299-304, 2001 | 335 | 2001 |
| Ultra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 mutations in noncancerous tissues JD Krimmel, MW Schmitt, MI Harrell, KJ Agnew, SR Kennedy, MJ Emond, ... Proceedings of the National Academy of Sciences 113 (21), 6005-6010, 2016 | 210 | 2016 |
| Ulcerative colitis is a disease of accelerated colon aging: evidence from telomere attrition and DNA damage RA Risques, LA Lai, TA Brentnall, L Li, Z Feng, J Gallaher, MT Mandelson, ... Gastroenterology 135 (2), 410-418, 2008 | 208 | 2008 |
| Aging and the rise of somatic cancer-associated mutations in normal tissues RA Risques, SR Kennedy PLoS genetics 14 (1), e1007108, 2018 | 201 | 2018 |
| Leukocyte telomere length predicts cancer risk in Barrett's esophagus RA Risques, TL Vaughan, X Li, RD Odze, PL Blount, K Ayub, JL Gallaher, ... Cancer Epidemiology and Prevention Biomarkers 16 (12), 2649-2655, 2007 | 168 | 2007 |
| Accelerated telomere shortening and replicative senescence in human fibroblasts overexpressing mutant and wild-type lamin A S Huang, RA Risques, GM Martin, PS Rabinovitch, J Oshima Experimental cell research 314 (1), 82-91, 2008 | 158 | 2008 |
| Methylome profiling of cancer cells by amplification of inter-methylated sites (AIMS) J Frigola, M Ribas, RA Risques, MA Peinado Nucleic acids research 30 (7), e28-e28, 2002 | 152 | 2002 |
| Ulcerative colitis–associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation RA Risques, LA Lai, C Himmetoglu, A Ebaee, L Li, Z Feng, MP Bronner, ... Cancer research 71 (5), 1669-1679, 2011 | 147 | 2011 |
| Independent and combined effects of dietary weight loss and exercise on leukocyte telomere length in postmenopausal women C Mason, RA Risques, L Xiao, CR Duggan, I Imayama, KL Campbell, ... Obesity 21 (12), E549-E554, 2013 | 121 | 2013 |
| Effect of heartfulness meditation on burnout, emotional wellness, and telomere length in health care professionals J Thimmapuram, R Pargament, K Sibliss, R Grim, R Risques, E Toorens Journal of community hospital internal medicine perspectives 7 (1), 21-27, 2017 | 113 | 2017 |
| Telomere length assessment in tissue sections by quantitative FISH: image analysis algorithms JN O'Sullivan, JC Finley, R Risques, WT Shen, KA Gollahon, ... Cytometry Part A: The Journal of the International Society for Analytical …, 2004 | 96 | 2004 |
| Telomere length in the colon declines with age: a relation to colorectal cancer? J O'Sullivan, RA Risques, MT Mandelson, L Chen, TA Brentnall, ... Cancer Epidemiology and Prevention Biomarkers 15 (3), 573-577, 2006 | 89 | 2006 |
| Change in peripheral blood leukocyte telomere length and mortality in breast cancer survivors C Duggan, R Risques, C Alfano, D Prunkard, I Imayama, S Holte, ... JNCI: Journal of the National Cancer Institute 106 (4), 2014 | 75 | 2014 |
| Ultra-sensitive TP53 sequencing for cancer detection reveals progressive clonal selection in normal tissue over a century of human lifespan JJ Salk, K Loubet-Senear, E Maritschnegg, CC Valentine, LN Williams, ... Cell reports 28 (1), 132-144. e3, 2019 | 74 | 2019 |
| Clonal expansions in ulcerative colitis identify patients with neoplasia JJ Salk, SJ Salipante, RA Risques, DA Crispin, L Li, MP Bronner, ... Proceedings of the National Academy of Sciences 106 (49), 20871-20876, 2009 | 68 | 2009 |
