| Whole-genome sequencing is more powerful than whole-exome sequencing for detecting exome variants A Belkadi, A Bolze, Y Itan, A Cobat, QB Vincent, A Antipenko, L Shang, ... Proceedings of the National Academy of Sciences 112 (17), 5473-5478, 2015 | 683 | 2015 |
| Characterization of Greater Middle Eastern genetic variation for enhanced disease gene discovery EM Scott, A Halees, Y Itan, EG Spencer, Y He, MA Azab, SB Gabriel, ... Nature genetics 48 (9), 1071-1076, 2016 | 345 | 2016 |
| The mutation significance cutoff: gene-level thresholds for variant predictions Y Itan, L Shang, B Boisson, MJ Ciancanelli, JG Markle, ... Nature methods 13 (2), 109-110, 2016 | 293 | 2016 |
| Genetic diagnosis using whole exome sequencing in common variable immunodeficiency P Maffucci, CA Filion, B Boisson, Y Itan, L Shang, JL Casanova, ... Frontiers in immunology 7, 203536, 2016 | 259 | 2016 |
| The human gene damage index as a gene-level approach to prioritizing exome variants Y Itan, L Shang, B Boisson, E Patin, A Bolze, M Moncada-Vélez, E Scott, ... Proceedings of the National Academy of Sciences 112 (44), 13615-13620, 2015 | 243 | 2015 |
| Whole-exome sequencing to analyze population structure, parental inbreeding, and familial linkage A Belkadi, V Pedergnana, A Cobat, Y Itan, QB Vincent, A Abhyankar, ... Proceedings of the National Academy of Sciences 113 (24), 6713-6718, 2016 | 68 | 2016 |
| Blacklisting variants common in private cohorts but not in public databases optimizes human exome analysis P Maffucci, B Bigio, F Rapaport, A Cobat, A Borghesi, M Lopez, E Patin, ... Proceedings of the National Academy of Sciences 116 (3), 950-959, 2019 | 63 | 2019 |
| Capturing the biology of disease severity in a PSC-based model of familial dysautonomia N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, ... Nature medicine 22 (12), 1421-1427, 2016 | 63 | 2016 |
| Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-β J Li, M Ritelli, CS Ma, G Rao, T Habib, E Corvilain, S Bougarn, S Cypowyj, ... Science immunology 4 (41), eaax7965, 2019 | 43 | 2019 |
| Structural constraints identified with covariation analysis in ribosomal RNA L Shang, W Xu, S Ozer, RR Gutell PLoS One 7 (6), e39383, 2012 | 34 | 2012 |
| Analysis of phage Mu DNA transposition by whole-genome Escherichia coli tiling arrays reveals a complex relationship to distribution of target selection protein B … J Ge, Z Lou, H Cui, L Shang, RM Harshey Journal of biosciences 36, 587-601, 2011 | 18 | 2011 |
| Molecular evolution and multilocus sequence typing of 145 strains of SARS-CoV ZG Wang, ZH Zheng, L Shang, LJ Li, LM Cong, MG Feng, Y Luo, ... FEBS letters 579 (22), 4928-4936, 2005 | 17 | 2005 |
| Two accurate sequence, structure, and phylogenetic template-based RNA alignment systems L Shang, DP Gardner, W Xu, JJ Cannone, DP Miranker, S Ozer, RR Gutell BMC Systems Biology 7, 1-15, 2013 | 11 | 2013 |
| RNA2DMap: A Visual Exploration Tool of the Information in RNA's Higher-Order Structure W Xu, A Wongsa, J Lee, L Shang, JJ Cannone, RR Gutell 2011 IEEE International Conference on Bioinformatics and Biomedicine, 613-617, 2011 | 9 | 2011 |
| CDG: an online server for detecting biologically closest disease-causing genes and its application to primary immunodeficiency D Requena, P Maffucci, B Bigio, L Shang, A Abhyankar, B Boisson, ... Frontiers in Immunology 9, 1340, 2018 | 8 | 2018 |
| Polymorphism of SARS-CoV genomes L Shang, QI Yan, BAO Qi-Yu, T Wei, XU Jian-Cheng, F Ming-Guang, ... Acta Genetica Sinica 33 (4), 354-364, 2006 | 4 | 2006 |
| CDG: an online server proposing biologically closest disease-causing genes and pathologies and its application to primary immunodeficiency D Requena, P Maffucci, B Bigio, L Shang, A Abhyankar, B Boisson, ... Frontiers in Immunology 9, 2018 | | 2018 |
| ELIMINATING NON-PATHOGENIC VARIATIONS FROM HUMAN EXOMES USING BLACKLISTS P Maffucci, Y Itan, B Boisson, L Shang, B Bigio, A Cobat, JL Casanova, ... JOURNAL OF CLINICAL IMMUNOLOGY 37 (2), 229-230, 2017 | | 2017 |
| FINDING A NEEDLE IN A HAYSTACK: NEW APPROACHES TO IDENTIFY DISEASE-CAUSING MUTATIONS IN PATIENTS'HIGH-THROUGHPUT SEQUENCING DATA Y Itan, L Shang, SY Zhang, B Boisson, L Abel, JL Casanova JOURNAL OF CLINICAL IMMUNOLOGY 36 (3), 238-239, 2016 | | 2016 |
| Characterization of Greater Middle Eastern genetic variation for enhanced disease gene discovery Nature Genetics 48, 1071-1076, 2016 | | 2016 |
