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Yuichi Umegawa
Yuichi Umegawa
Bestätigte E-Mail-Adresse bei chem.sci.osaka-u.ac.jp
Titel
Zitiert von
Zitiert von
Jahr
Self‐Assembled Amphotericin B Is Probably Surrounded by Ergosterol: Bimolecular Interactions as Evidenced by Solid‐State NMR and CD Spectra
Y Kasai, N Matsumori, Y Umegawa, S Matsuoka, H Ueno, H Ikeuchi, ...
Chemistry–A European Journal 14 (4), 1178-1185, 2008
562008
Head-to-tail interaction between amphotericin B and ergosterol occurs in hydrated phospholipid membrane
Y Umegawa, Y Nakagawa, K Tahara, H Tsuchikawa, N Matsumori, ...
Biochemistry 51 (1), 83-89, 2012
492012
Ergosterol increases the intermolecular distance of amphotericin B in the membrane-bound assembly as evidenced by solid-state NMR
Y Umegawa, N Matsumori, T Oishi, M Murata
Biochemistry 47 (51), 13463-13469, 2008
462008
Bioactive fluorinated derivative of amphotericin B
N Matsumori, Y Umegawa, T Oishi, M Murata
Bioorganic & medicinal chemistry letters 15 (15), 3565-3567, 2005
372005
Membrane interaction of amphotericin B as single-length assembly examined by solid state NMR for uniformly 13C-enriched agent
S Matsuoka, H Ikeuchi, Y Umegawa, N Matsumori, M Murata
Bioorganic & medicinal chemistry 14 (19), 6608-6614, 2006
322006
The structure of the bimolecular complex between amphotericin B and ergosterol in membranes is stabilized by face-to-face van der Waals interaction with their rigid cyclic cores
Y Nakagawa, Y Umegawa, N Matsushita, T Yamamoto, H Tsuchikawa, ...
Biochemistry 55 (24), 3392-3402, 2016
292016
The perpendicular orientation of amphotericin B methyl ester in hydrated lipid bilayers supports the barrel-stave model
T Yamamoto, Y Umegawa, M Yamagami, T Suzuki, H Tsuchikawa, ...
Biochemistry 58 (17), 2282-2291, 2019
272019
Amphotericin B covalent dimers with carbonyl-amino linkage: a new probe for investigating ion channel assemblies
Y Umegawa, N Matsumori, T Oishi, M Murata
Tetrahedron letters 48 (19), 3393-3396, 2007
272007
The amphotericin B–ergosterol complex spans a lipid bilayer as a single-length assembly
T Yamamoto, Y Umegawa, H Tsuchikawa, S Hanashima, N Matsumori, ...
Biochemistry 58 (51), 5188-5196, 2019
252019
Ion channel complex of antibiotics as viewed by NMR
M Murata, Y Kasai, Y Umegawa, N Matsushita, H Tsuchikawa, ...
Pure and Applied Chemistry 81 (6), 1123-1129, 2009
232009
Amphotericin B assembles into seven-molecule ion channels: An NMR and molecular dynamics study
Y Umegawa, T Yamamoto, M Dixit, K Funahashi, S Seo, Y Nakagawa, ...
Science Advances 8 (24), eabo2658, 2022
212022
Effect of sterol side chain on ion channel formation by amphotericin B in lipid bilayers
Y Nakagawa, Y Umegawa, T Takano, H Tsuchikawa, N Matsumori, ...
Biochemistry 53 (19), 3088-3094, 2014
212014
Axial hydrogen at C7 position and bumpy tetracyclic core markedly reduce sterol’s affinity to amphotericin B in membrane
Y Nakagawa, Y Umegawa, K Nonomura, N Matsushita, T Takano, ...
Biochemistry 54 (2), 303-312, 2015
202015
Cholesterol-induced conformational change in the sphingomyelin headgroup
S Hanashima, K Murakami, M Yura, Y Yano, Y Umegawa, H Tsuchikawa, ...
Biophysical Journal 117 (2), 307-318, 2019
162019
Role of polyol moiety of amphotericin B in ion channel formation and sterol selectivity in bilayer membrane
T Yamamoto, Y Umegawa, H Tsuchikawa, N Matsumori, S Hanashima, ...
Bioorganic & medicinal chemistry 23 (17), 5782-5788, 2015
152015
Evaluation of diacylphospholipids as boundary lipids for bacteriorhodopsin from structural and functional aspects
S Kawatake, Y Umegawa, S Matsuoka, M Murata, M Sonoyama
Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (9), 2106-2115, 2016
142016
Stereoselective synthesis of the head group of archaeal phospholipid PGP-Me to investigate bacteriorhodopsin–lipid interactions
J Cui, S Kawatake, Y Umegawa, S Lethu, M Yamagami, S Matsuoka, ...
Organic & Biomolecular Chemistry 13 (41), 10279-10284, 2015
112015
Diosgenin-induced physicochemical effects on phospholipid bilayers in comparison with cholesterol
JC Ondevilla, S Hanashima, A Mukogawa, Y Umegawa, M Murata
Bioorganic & Medicinal Chemistry Letters 36, 127816, 2021
92021
Average conformation of branched chain lipid PGP-Me that accounts for the thermal stability and high-salinity resistance of archaeal membranes
M Yamagami, H Tsuchikawa, J Cui, Y Umegawa, Y Miyazaki, S Seo, ...
Biochemistry 58 (37), 3869-3879, 2019
92019
13C‐TmDOTA as versatile thermometer compound for solid‐state NMR of hydrated lipid bilayer membranes
Y Umegawa, Y Tanaka, M Nobuaki, M Murata
Magnetic Resonance in Chemistry 54 (3), 227-233, 2016
82016
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