| Role of mitochondrial DNA in toxic responses to oxidative stress B Van Houten, V Woshner, JH Santos DNA repair 5 (2), 145-152, 2006 | 540 | 2006 |
| TCA cycle and mitochondrial membrane potential are necessary for diverse biological functions I Martínez-Reyes, LP Diebold, H Kong, M Schieber, H Huang, CT Hensley, ... Molecular cell 61 (2), 199-209, 2016 | 510 | 2016 |
| Mitochondrial DNA repair and aging BS Mandavilli, JH Santos, B Van Houten Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 509 (1 …, 2002 | 475 | 2002 |
| Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells JH Santos, JN Meyer, BS Mandavilli, B Van Houten DNA repair protocols: mammalian systems, 183-199, 2006 | 360 | 2006 |
| Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance HY Lee, CS Choi, AL Birkenfeld, TC Alves, FR Jornayvaz, MJ Jurczak, ... Cell metabolism 12 (6), 668-674, 2010 | 349 | 2010 |
| Mitochondrial hTERT exacerbates free‐radical‐mediated mtDNA damage JH Santos, JN Meyer, M Skorvaga, LA Annab, B Van Houten Aging cell 3 (6), 399-411, 2004 | 312 | 2004 |
| Mitochondria, energetics, epigenetics, and cellular responses to stress DT Shaughnessy, K McAllister, L Worth, AC Haugen, JN Meyer, ... Environmental health perspectives 122 (12), 1271-1278, 2014 | 257 | 2014 |
| MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer PC Hart, M Mao, ALP De Abreu, K Ansenberger-Fricano, DN Ekoue, ... Nature communications 6 (1), 6053, 2015 | 252 | 2015 |
| Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death JH Santos, L Hunakova, Y Chen, C Bortner, B Van Houten Journal of Biological Chemistry 278 (3), 1728-1734, 2003 | 246 | 2003 |
| Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis JH Santos, JN Meyer, B Van Houten Human molecular genetics 15 (11), 1757-1768, 2006 | 242 | 2006 |
| Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria NK Sharma, A Reyes, P Green, MJ Caron, MG Bonini, DM Gordon, IJ Holt, ... Nucleic acids research 40 (2), 712-725, 2012 | 195 | 2012 |
| Measuring oxidative mtDNA damage and repair using quantitative PCR JH Santos, BS Mandavilli, B Van Houten Mitochondrial DNA: methods and protocols, 159-176, 2002 | 178 | 2002 |
| Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance B Lu, S Yadav, PG Shah, T Liu, B Tian, S Pukszta, N Villaluna, ... Journal of Biological Chemistry 282 (24), 17363-17374, 2007 | 162 | 2007 |
| Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APCMin/+ mice DK Woo, PD Green, JH Santos, AD D'Souza, Z Walther, WD Martin, ... The American journal of pathology 180 (1), 24-31, 2012 | 143 | 2012 |
| Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells A Furda, JH Santos, JN Meyer, B Van Houten Molecular Toxicology Protocols, 419-437, 2014 | 141 | 2014 |
| Reduction in frataxin causes progressive accumulation of mitochondrial damage G Karthikeyan, JH Santos, MA Graziewicz, WC Copeland, G Isaya, ... Human molecular genetics 12 (24), 3331-3342, 2003 | 117 | 2003 |
| A mutant telomerase defective in nuclear‐cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction OA Kovalenko, MJ Caron, P Ulema, C Medrano, AP Thomas, M Kimura, ... Aging cell 9 (2), 203-219, 2010 | 111 | 2010 |
| Critical role for telomerase in the mechanism of flow-mediated dilation in the human microcirculation AM Beyer, JK Freed, MJ Durand, M Riedel, K Ait-Aissa, P Green, ... Circulation research 118 (5), 856-866, 2016 | 107 | 2016 |
| Selected mitochondrial DNA landscapes activate the SIRT3 axis of the UPRmt to promote metastasis TC Kenny, P Hart, M Ragazzi, M Sersinghe, J Chipuk, MAK Sagar, ... Oncogene 36 (31), 4393-4404, 2017 | 93 | 2017 |
| Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation OA Lozoya, I Martinez-Reyes, T Wang, D Grenet, P Bushel, J Li, ... PLoS biology 16 (4), e2005707, 2018 | 90 | 2018 |
