| Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes MD Eldridge, CW Murray, TR Auton, GV Paolini, RP Mee Journal of computer-aided molecular design 11, 425-445, 1997 | 2204 | 1997 |
| Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1706* | 2020 |
| Enhanced detection of circulating tumor DNA by fragment size analysis F Mouliere, D Chandrananda, AM Piskorz, EK Moore, J Morris, ... Science translational medicine 10 (466), eaat4921, 2018 | 819 | 2018 |
| Flexible docking using Tabu search and an empirical estimate of binding affinity CA Baxter, CW Murray, DE Clark, DR Westhead, MD Eldridge Proteins: Structure, Function, and Bioinformatics 33 (3), 367-382, 1998 | 540 | 1998 |
| A biobank of breast cancer explants with preserved intra-tumor heterogeneity to screen anticancer compounds A Bruna, OM Rueda, W Greenwood, AS Batra, M Callari, RN Batra, ... Cell 167 (1), 260-274. e22, 2016 | 445 | 2016 |
| Entropy-driven formation of a superlattice in a hard-sphere binary mixture MD Eldridge, PA Madden, D Frenkel Nature 365 (6441), 35-37, 1993 | 390 | 1993 |
| Copy number signatures and mutational processes in ovarian carcinoma G Macintyre, TE Goranova, D De Silva, D Ennis, AM Piskorz, M Eldridge, ... Nature genetics 50 (9), 1262-1270, 2018 | 380 | 2018 |
| Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis JMJ Weaver, CS Ross-Innes, N Shannon, AG Lynch, T Forshew, ... Nature genetics 46 (8), 837-843, 2014 | 374 | 2014 |
| Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance M Secrier, X Li, N De Silva, MD Eldridge, G Contino, J Bornschein, ... Nature genetics 48 (10), 1131-1141, 2016 | 356 | 2016 |
| A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing TS Alioto, I Buchhalter, S Derdak, B Hutter, MD Eldridge, E Hovig, ... Nature communications 6 (1), 1-13, 2015 | 322 | 2015 |
| Whole-genome sequencing provides new insights into the clonal architecture of Barrett's esophagus and esophageal adenocarcinoma CS Ross-Innes, J Becq, A Warren, RK Cheetham, H Northen, ... Nature genetics 47 (9), 1038-1046, 2015 | 299 | 2015 |
| Cooperative interaction between retinoic acid receptor-α and estrogen receptor in breast cancer CS Ross-Innes, R Stark, KA Holmes, D Schmidt, C Spyrou, R Russell, ... Genes & development 24 (2), 171-182, 2010 | 285 | 2010 |
| Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis HN March, AG Rust, NA Wright, J ten Hoeve, J de Ridder, M Eldridge, ... Nature genetics 43 (12), 1202-1209, 2011 | 209 | 2011 |
| Empirical scoring functions. II. The testing of an empirical scoring function for the prediction of ligand-receptor binding affinities and the use of Bayesian regression to … CW Murray, TR Auton, MD Eldridge Journal of computer-aided molecular design 12, 503-519, 1998 | 203 | 1998 |
| The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic AM Frankell, SG Jammula, X Li, G Contino, S Killcoyne, S Abbas, J Perner, ... Nature genetics 51 (3), 506-516, 2019 | 189 | 2019 |
| Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours L Harewood, K Kishore, MD Eldridge, S Wingett, D Pearson, ... Genome biology 18, 1-11, 2017 | 158 | 2017 |
| Representing and analysing molecular and cellular function in the computer J Van Helden, A Naim, R Mancuso, M Eldridge, L Wernisch, D Gilbert, ... Biological chemistry 381 (9-10), 921-935, 2000 | 154 | 2000 |
| ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung MJ Schuijs, S Png, AC Richard, A Tsyben, G Hamm, J Stockis, C Garcia, ... Nature immunology 21 (9), 998-1009, 2020 | 134 | 2020 |
| The stability of the AB 13 crystal in a binary hard sphere system MD Eldridge, PA Madden, D Frenkel Molecular physics 79 (1), 105-120, 1993 | 127 | 1993 |
| A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes EK Papachristou, K Kishore, AN Holding, K Harvey, TI Roumeliotis, ... Nature communications 9 (1), 2311, 2018 | 120 | 2018 |
Rebecca FitzgeraldProfessor of Cancer Prevention, Cambridge UniversityEmail verificata su cam.ac.uk
