| Novel short-acting A2A adenosine receptor agonists for coronary vasodilation: inverse relationship between affinity and duration of action of A2A agonists Z Gao, Z Li, SP Baker, RD Lasley, S Meyer, E Elzein, V Palle, JA Zablocki, ... Journal of Pharmacology and Experimental therapeutics 298 (1), 209-218, 2001 | 143 | 2001 |
| N6 heterocyclic 8-modified adenosine derivatives JA Zablocki, VP Palle, PN Ibrahim, L Belardenelli US Patent 6,294,522, 2001 | 98 | 2001 |
| A2B adenosine receptor antagonists R Kalla, T Perry, E Elzein, V Varkhedkar, X Li, P Ibrahim, V Palle, D Xiao, ... US Patent 6,825,349, 2004 | 96* | 2004 |
| N-pyrazole A2A adenosine receptor agonists JA Zablocki, EO Elzein, VP Palle US Patent 6,403,567, 2002 | 83 | 2002 |
| Novel 1,3-Disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) Xanthines: High Affinity and Selective A2B Adenosine Receptor Antagonists RV Kalla, E Elzein, T Perry, X Li, V Palle, V Varkhedkar, A Gimbel, T Maa, ... Journal of medicinal chemistry 49 (12), 3682-3692, 2006 | 82 | 2006 |
| Discovery of a potent and selective small molecule hGPR91 antagonist D Bhuniya, D Umrani, B Dave, D Salunke, G Kukreja, J Gundu, M Naykodi, ... Bioorganic & medicinal chemistry letters 21 (12), 3596-3602, 2011 | 81 | 2011 |
| Partial or full A1agonists-N-6 heterocyclic 5′-thio substituted adenosine derivatives JA Zablocki, VP Palle, V Varkhedkar, L Belardinelli US Patent 6,605,597, 2003 | 76 | 2003 |
| Efficient synthesis of isoxazoles and isoxazolines from aldoximes using Magtrieve™(CrO2) S Bhosale, S Kurhade, UV Prasad, VP Palle, D Bhuniya Tetrahedron Letters 50 (27), 3948-3951, 2009 | 73 | 2009 |
| The discovery of a selective, high affinity A2B adenosine receptor antagonist for the potential treatment of asthma J Zablocki, R Kalla, T Perry, V Palle, V Varkhedkar, D Xiao, A Piscopio, ... Bioorganic & medicinal chemistry letters 15 (3), 609-612, 2005 | 73 | 2005 |
| C-pyrazole 2A A receptor agonists JA Zablocki, VP Palle, EO Elzein US Patent 6,214,807, 2001 | 60 | 2001 |
| A partial agonist of the A1-adenosine receptor selectively slows AV conduction in guinea pig hearts LIN Wu, L Belardinelli, JA Zablocki, V Palle, JC Shryock American Journal of Physiology-Heart and Circulatory Physiology 280 (1 …, 2001 | 57 | 2001 |
| Novel 1, 3-dipropyl-8-(1-heteroarylmethyl-1H-pyrazol-4-yl)-xanthine derivatives as high affinity and selective A2B adenosine receptor antagonists E Elzein, R Kalla, X Li, T Perry, E Parkhill, V Palle, V Varkhedkar, ... Bioorganic & medicinal chemistry letters 16 (2), 302-306, 2006 | 55 | 2006 |
| Substituted piperazine compounds J Zablocki, E Elzein, G Nudelman, T Marquart, BK Blackburn, VP Palle US Patent 6,677,336, 2004 | 54 | 2004 |
| C-pyrazole A2A receptor agonists JA Zablocki, EO Elzein, VP Palle US Patent 7,553,823, 2009 | 52 | 2009 |
| Aralkyl substituted piperazine compounds J Zablocki, E Elzein, BK Blackburn, T Marquart, PN Ibrahim, VP Palle US Patent 6,552,023, 2003 | 50 | 2003 |
| 2-Pyrazolyl-N6-substituted adenosine derivatives as high affinity and selective adenosine A3 receptor agonists E Elzein, V Palle, Y Wu, T Maa, D Zeng, J Zablocki Journal of medicinal chemistry 47 (19), 4766-4773, 2004 | 47 | 2004 |
| 2-(N-pyrazolo) adenosines with application as adenosine A2A receptor agonists JA Zablocki, EO Elzein, VP Palle US Patent 6,642,210, 2003 | 44 | 2003 |
| Heteroaryl alkyl piperazine derivatives J Zablocki, PN Ibrahim, K Shenk, E Elzein, V Palle US Patent 6,573,264, 2003 | 41 | 2003 |
| 2-substituted pi system derivatives of adenosine that are coronary vasodilators acting via the A2A adenosine receptor J Zablocki, V Palle, B Blackburn, E Elzein, G Nudelman, S Gothe, Z Gao, ... Nucleosides, Nucleotides and Nucleic Acids 20 (4-7), 343-360, 2001 | 41 | 2001 |
| N-pyrazole A2A receptor agonists JA Zablocki, EO Elzein, V Palle, L Belardinelli US Patent 7,144,872, 2006 | 40 | 2006 |
