Geza Ambrus
Geza Ambrus
Jecure Therapeutics
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Natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and-2: a study on recombinant catalytic fragments
G Ambrus, P Gál, M Kojima, K Szilágyi, J Balczer, J Antal, L Gráf, A Laich, ...
The Journal of Immunology 170 (3), 1374-1382, 2003
The biological functions of MBL-associated serine proteases (MASPs)
K Hajela, M Kojima, G Ambrus, KHN Wong, BE Moffatt, J Ferluga, ...
Immunobiology 205 (4-5), 467-475, 2002
Differential substrate and inhibitor profiles for human MASP-1 and MASP-2
JS Presanis, K Hajela, G Ambrus, P Gál, RB Sim
Molecular immunology 40 (13), 921-929, 2004
Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production
S Naji, G Ambrus, P Cimermančič, JR Reyes, JR Johnson, R Filbrandt, ...
Molecular & Cellular Proteomics 11 (4), 2012
A true autoactivating enzyme: structural insight into mannose-binding lectin-associated serine protease-2 activations
P Gál, V Harmat, A Kocsis, T Bián, L Barna, G Ambrus, B Végh, J Balczer, ...
Journal of Biological Chemistry 280 (39), 33435-33444, 2005
The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme–substrate …
V Harmat, P Gal, J Kardos, K Szilagyi, G Ambrus, B Vegh, G Naray-Szabo, ...
Journal of molecular biology 342 (5), 1533-1546, 2004
Activities of the MBL-associated serine proteases (MASPs) and their regulation by natural inhibitors
NKH Wong, M Kojima, J Dobo, G Ambrus, RB Sim
Molecular immunology 36 (13-14), 853-861, 1999
DDX1 is an RNA-dependent ATPase involved in HIV-1 Rev function and virus replication
SP Edgcomb, AB Carmel, S Naji, G Ambrus-Aikelin, JR Reyes, ...
Journal of molecular biology 415 (1), 61-74, 2012
Identification of a small molecule inhibitor of importin β mediated nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries
M Hintersteiner, G Ambrus, J Bednenko, M Schmied, AJS Knox, ...
ACS chemical biology 5 (10), 967-979, 2010
Structure and function of complement activating enzyme complexes C1 and MBL-MASPs
P Gal, G Ambrus
Current Protein and Peptide Science 2 (1), 43-59, 2001
Small molecule peptidomimetic inhibitors of importin α/β mediated nuclear transport
G Ambrus, LR Whitby, EL Singer, O Trott, E Choi, AJ Olson, DL Boger, ...
Bioorganic & medicinal chemistry 18 (21), 7611-7620, 2010
Folded recombinant catalytic fragments of multidomain serine proteases, preparation and uses thereof
P Gál, P Závodszky, G Ambrus-Aikelin, J Kardos
US Patent 7,666,627, 2010
A neural network based classification scheme for cytotoxicity predictions: Validation on 30,000 compounds
L Molnár, GM Keserű, Á Papp, Z Lőrincz, G Ambrus, F Darvas
Bioorganic & medicinal chemistry letters 16 (4), 1037-1039, 2006
C1s, the protease messenger of C1
P Gál, G Ambrus, P Závodszky
Immunobiology 205 (4-5), 383-394, 2002
The cleavage of two C1s subunits by a single active C1r reveals substantial flexibility of the C1s-C1r-C1r-C1s tetramer in the C1 complex
Z Lörincz, P Gál, J Dobó, S Cseh, K Szilágyi, G Ambrus, P Závodszky
The Journal of Immunology 165 (4), 2048-2051, 2000
Folded recombinant catalytic fragments of multidomain serine proteases, preparation and uses thereof
P Gál, P Závodszky, G Ambrus-Aikelin, J Kardos
US Patent 8,173,397, 2012
The structure of the NXF2/NXT1 heterodimeric complex reveals the combined specificity and versatility of the NTF2-like fold
DE Kerkow, AB Carmel, E Menichelli, G Ambrus, RD Hills Jr, L Gerace, ...
Journal of molecular biology 415 (4), 649-665, 2012
A Fragment-Based Approach to Identifying S-Adenosyl-l-methionine -Competitive Inhibitors of Catechol O-Methyl Transferase (COMT).
M Lanier, G Ambrus, DC Cole, R Davenport, J Ellery, R Fosbeary, ...
Journal of Medicinal Chemistry 57 (12), 5459-5463, 2014
OpenMolGRID, a GRID based system for solving large-scale drug design problems
F Darvas, Á Papp, I Bágyi, G Ambrus, L Ürge
European Across Grids Conference, 69-76, 2004
The initiation complexes of the classical and lectin pathways
P Gál, G Ambrus, Z Lőrincz, P Závodszky
The Complement System, 19-43, 2004
Il sistema al momento non puň eseguire l'operazione. Riprova piů tardi.
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