David Scadden
David Scadden
Verified email at mgh.harvard.edu - Homepage
TitleCited byYear
Osteoblastic cells regulate the haematopoietic stem cell niche
LM Calvi, GB Adams, KW Weibrecht, JM Weber, DP Olson, MC Knight, ...
Nature 425 (6960), 841, 2003
35922003
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
S Méndez-Ferrer, TV Michurina, F Ferraro, AR Mazloom, BD MacArthur, ...
Nature 466 (7308), 829, 2010
25102010
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
CG Willett, Y Boucher, E Di Tomaso, DG Duda, LL Munn, RT Tong, ...
Nature medicine 10 (2), 145, 2004
21792004
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
CG Willett, Y Boucher, E Di Tomaso, DG Duda, LL Munn, RT Tong, ...
Nature medicine 10 (2), 145, 2004
21792004
Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
M Lewin, N Carlesso, CH Tung, XW Tang, D Cory, DT Scadden, ...
Nature biotechnology 18 (4), 410, 2000
20782000
The stem-cell niche as an entity of action
DT Scadden
Nature 441 (7097), 1075, 2006
18922006
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
TT Batchelor, AG Sorensen, E di Tomaso, WT Zhang, DG Duda, ...
Cancer cell 11 (1), 83-95, 2007
17882007
Hematopoietic stem cell quiescence maintained by p21cip1/waf1
T Cheng, N Rodrigues, H Shen, Y Yang, D Dombkowski, M Sykes, ...
Science 287 (5459), 1804-1808, 2000
13972000
The bone marrow niche for haematopoietic stem cells
SJ Morrison, DT Scadden
Nature 505 (7483), 327-334, 2014
13092014
Biology of hematopoietic stem cells and progenitors: implications for clinical application
M Kondo, AJ Wagers, MG Manz, SS Prohaska, DC Scherer, GF Beilhack, ...
Annual review of immunology 21 (1), 759-806, 2003
11662003
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
V Janzen, R Forkert, HE Fleming, Y Saito, MT Waring, DM Dombkowski, ...
Nature 443 (7110), 421, 2006
10772006
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
MHGP Raaijmakers, S Mukherjee, S Guo, S Zhang, T Kobayashi, ...
Nature 464 (7290), 852, 2010
9032010
In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment
DA Sipkins, X Wei, JW Wu, JM Runnels, D Côté, TK Means, AD Luster, ...
Nature 435 (7044), 969, 2005
8492005
Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation
KW Orford, DT Scadden
Nature Reviews Genetics 9 (2), 115, 2008
8022008
A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection
LM Albritton, L Tseng, D Scadden, JM Cunningham
Cell 57 (4), 659-666, 1989
7901989
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
CL Celso, HE Fleming, JW Wu, CX Zhao, S Miake-Lye, J Fujisaki, D Côté, ...
Nature 457 (7225), 92, 2009
7812009
Oocyte generation in adult mammalian ovaries by putative germ cells in bone marrow and peripheral blood
J Johnson, J Bagley, M Skaznik-Wikiel, HJ Lee, GB Adams, Y Niikura, ...
Cell 122 (2), 303-315, 2005
7492005
Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor
GB Adams, KT Chabner, IR Alley, DP Olson, ZM Szczepiorkowski, ...
Nature 439 (7076), 599, 2006
7472006
Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size
S Stier, Y Ko, R Forkert, C Lutz, T Neuhaus, E Grünewald, T Cheng, ...
Journal of Experimental Medicine 201 (11), 1781-1791, 2005
6522005
Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells
JS Duffield, KM Park, LL Hsiao, VR Kelley, DT Scadden, T Ichimura, ...
The Journal of clinical investigation 115 (7), 1743-1755, 2005
6242005
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