A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity Z Ahmed, J Cooper, TK Murray, K Garn, E McNaughton, H Clarke, ... Acta neuropathologica 127, 667-683, 2014 | 495 | 2014 |
Conformation determines the seeding potencies of native and recombinant Tau aggregates B Falcon, A Cavallini, R Angers, S Glover, TK Murray, L Barnham, ... Journal of biological chemistry 290 (2), 1049-1065, 2015 | 286 | 2015 |
Short fibrils constitute the major species of seed-competent tau in the brains of mice transgenic for human P301S tau SJ Jackson, C Kerridge, J Cooper, A Cavallini, B Falcon, CV Cella, ... Journal of Neuroscience 36 (3), 762-772, 2016 | 151 | 2016 |
An unbiased approach to identifying tau kinases that phosphorylate tau at sites associated with Alzheimer disease A Cavallini, S Brewerton, A Bell, S Sargent, S Glover, C Hardy, R Moore, ... Journal of Biological Chemistry 288 (32), 23331-23347, 2013 | 140 | 2013 |
Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model H Wang, Y Li, JW Ryder, JT Hole, PJ Ebert, DC Airey, HR Qian, ... Molecular neurodegeneration 13, 1-19, 2018 | 60 | 2018 |
Tau protein aggregates inhibit the protein-folding and vesicular trafficking arms of the cellular proteostasis network A Yu, SG Fox, A Cavallini, C Kerridge, MJ O’Neill, J Wolak, S Bose, ... Journal of Biological Chemistry 294 (19), 7917-7930, 2019 | 48 | 2019 |
Quantitative propagation of assembled human Tau from Alzheimer's disease brain in microfluidic neuronal cultures A Katsikoudi, E Ficulle, A Cavallini, G Sharman, A Guyot, M Zagnoni, ... Journal of Biological Chemistry 295 (37), 13079-13093, 2020 | 27 | 2020 |
Determination of amphetamines in human urine by liquid chromatography with fluorimetric detection using a solid‐phase extraction procedure F Bugamelli, R Mandrioli, A Cavallini, C Baccini, M Conti, MA Raggi Journal of separation science 29 (15), 2322-2329, 2006 | 12 | 2006 |
Development of P301S tau seeded organotypic hippocampal slice cultures to study potential therapeutics JM McCarthy, J Virdee, J Brown, D Ursu, Z Ahmed, A Cavallini, ... Scientific Reports 11 (1), 10309, 2021 | 4 | 2021 |
[O2–14–04]: AGGREGATE‐SELECTIVE ANTI‐TAU ANTIBODY MC‐1 DEMONSTRATED ROBUST IN VITRO AND IN VIVO ACTIVITY TO NEUTRALIZE TRANSMISSIBLE TAU AND REDUCE TAU PATHOLOGY ML Hayashi, J Lu, S Wu, S Bose, Z Ahmed, J Cooper, TK Murray, ... Alzheimer's & Dementia 13 (7S_Part_11), P592-P592, 2017 | 3 | 2017 |
Synaptic alterations associated with disrupted sensory encoding in a mouse model of tauopathy S Meftah, A Cavallini, TK Murray, L Jankowski, S Bose, MC Ashby, ... bioRxiv, 2023.05. 24.542163, 2023 | 1 | 2023 |
Identifying early markers of synaptic dysfunction in a mouse model of tauopathy: Molecular and cell biology/synaptic disruption S Meftah, J Witton, A Cavallini, TK Murray, L Jankowski, S Bose, M Ashby, ... Alzheimer's & Dementia 16, e040342, 2020 | | 2020 |
Identifying early markers of synaptic dysfunction in a mouse model of tauopathy S Meftah, J Witton, A Cavallini, TK Murray, L Jankowski, S Bose, M Ashby, ... 2020 Alzheimer's Association International Conference, 2020 | | 2020 |
Development and characterization of cell models of tau aggregation A Cavallini UCL (University College London), 2018 | | 2018 |
Developing an in vivo model of tau propagation using tau aggregates derived from Alzheimer's Disease brain tissue J Cooper, G Portlock, A Guyot, T Vargova, C Kerridge, T Murray, M Ward, ... NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 44, 19-19, 2018 | | 2018 |
[P3–081]: ESTABLISHING MICROFLUIDIC DEVICES AS AN IN VITRO NEURONAL MODEL FOR STUDYING MOLECULAR AND FUNCTIONAL ASPECTS OF … A Katsikoudi, C Soubrane, O Grubisha, A Fouillet, A Cavallini, S Bose, ... Alzheimer's & Dementia 13 (7S_Part_20), P963-P963, 2017 | | 2017 |
[O3–04–02]: DEVELOPING IN VIVO MODELS OF TAU PROPAGATION WHICH ARE RELEVANT TO HUMAN DISEASE PATHOGENESIS AND APPLICABLE TO … Z Ahmed, J Cooper, C Kerridge, T Vargova, A Fisher, TK Murray, M Ward, ... Alzheimer's & Dementia 13 (7S_Part_18), P906-P906, 2017 | | 2017 |
Transection of targeted axonal pathways inhibits network spread of tau pathology in a P301S model of tau propagation A Fisher, Z Ahmed, J Cooper, K Jackson, TK Murray, A Cavallini, S Bose, ... NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 43, 26-26, 2017 | | 2017 |
O4‐04‐02: Characterisation of Tau Species Involved in Tau Seeding and Spread in Cellular and Animal Models S Bose, A Cavallini, C Kerridge, J Cooper, SJ Jackson, A Landi, CV Cella, ... Alzheimer's & Dementia 12, P340-P340, 2016 | | 2016 |
P3‐065: Transection of Targeted Axonal Pathways Inhibits Network Spread of Tau Pathology in a P301S Model of TAU Propagation Z Ahmed, J Cooper, A Fisher, K Jackson, TK Murray, A Cavallini, S Bose, ... Alzheimer's & Dementia 12, P842-P842, 2016 | | 2016 |