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Silvano Sanchini
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Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism
JR Clapper, G Moreno-Sanz, R Russo, A Guijarro, F Vacondio, A Duranti, ...
Nature neuroscience 13 (10), 1265-1270, 2010
3732010
A second generation of carbamate‐based fatty acid amide hydrolase inhibitors with improved activity in vivo
JR Clapper, F Vacondio, AR King, A Duranti, A Tontini, C Silva, ...
ChemMedChem: Chemistry Enabling Drug Discovery 4 (9), 1505-1513, 2009
882009
Synthesis and quantitative structure− activity relationship of fatty acid amide hydrolase inhibitors: Modulation at the N-portion of biphenyl-3-yl alkylcarbamates
M Mor, A Lodola, S Rivara, F Vacondio, A Duranti, A Tontini, S Sanchini, ...
Journal of medicinal chemistry 51 (12), 3487-3498, 2008
782008
Structure–Property Relationships of a Class of Carbamate‐Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability
F Vacondio, C Silva, A Lodola, A Fioni, S Rivara, A Duranti, A Tontini, ...
ChemMedChem: Chemistry Enabling Drug Discovery 4 (9), 1495-1504, 2009
502009
Design, synthesis, and biological evaluation of a biyouyanagin compound library
KC Nicolaou, S Sanchini, D Sarlah, G Lu, TR Wu, DK Nomura, BF Cravatt, ...
Proceedings of the National Academy of Sciences 108 (17), 6715-6720, 2011
372011
Synthesis and Structure–Activity Relationship Studies of O-Biphenyl-3-yl Carbamates as Peripherally Restricted Fatty Acid Amide Hydrolase Inhibitors
G Moreno-Sanz, A Duranti, L Melzig, C Fiorelli, GF Ruda, G Colombano, ...
Journal of medicinal chemistry 56 (14), 5917-5930, 2013
272013
Total synthesis and structural revision of biyouyanagin B
KC Nicolaou, S Sanchini, TR Wu, D Sarlah
Chemistry (Weinheim an der Bergstrasse, Germany) 16 (26), 7678, 2010
272010
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability
F Vacondio, C Silva, A Lodola, C Carmi, S Rivara, A Duranti, A Tontini, ...
European journal of medicinal chemistry 46 (9), 4466-4473, 2011
232011
Facile solid-phase synthesis and assessment of nucleoside analogs as inhibitors of bacterial UDP-sugar processing enzymes
AGE Madec, NS Schocker, S Sanchini, G Myratgeldiyev, D Das, ...
ACS chemical biology 13 (9), 2542-2550, 2018
122018
Rational design, synthesis and biological evaluation of modular fluorogenic substrates with high affinity and selectivity for PTP1B
S Sanchini, F Perruccio, G Piizzi
ChemBioChem 15 (7), 961-976, 2014
62014
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies
P Mestichelli, G MORENO SANZ, A Duranti, S Sanchini, A Tontini, ...
13° SAYCS Riccione 28-30 Ottobre 2013, P21 (Poster), 2013
2013
Sintesi e studi di relazione struttura–attività/selettività su O-bifenil-3-ilcarbammati disostituiti quali inibitori periferici dell’enzima FAAH
P Mestichelli, G MORENO SANZ, A Duranti, S Sanchini, A Tontini, ...
TUMA 2013 Sesto Fiorentino (FI) 1-2 Luglio 2013 OC23, 28 (Comunicazione orale), 2013
2013
Sintesi e studi biologici preliminari su analoghi di URB937, il primo inibitore ad azione periferica dell'enzima FAAH
P Mestichelli, A Duranti, S Sanchini, A Tontini, G Tarzia, A Lodola, ...
11° SAYCS Pesaro 17-19 Ottobre 2011, P19 (Poster), 2011
2011
Perspectives on Neuroscience and Behavior
JR Clapper, G Moreno-Sanz, R Russo, A Guijarro, F Vacondio, A Duranti, ...
2011
Scoperta del primo inibitore dell’enzima idrolasi delle ammidi degli acidi grassi (FAAH) ad azione periferica
S Sanchini, A Duranti, A Tontini, G Tarzia, A Lodola, S Rivara, F Vacondio, ...
10° SAYCS, Pesaro 18-20 Ottobre 2010, O20 (Comunicazione orale), 2010
2010
Synthesis and Structure-Activity/Stability Relationships of Carbamate Inhibitors of the FAAH Enzyme
S Sanchini, A Duranti, A Tontini, G Tarzia, F Vacondio, A Fioni, A Lodola, ...
Nuove prospettive in chimica farmaceutica III° meeting-workshop Il Ciocco …, 2009
2009
Sintesi e studi di relazione struttura-attività/stabilità di carbammati inibitori dell’enzima FAAH
S Sanchini, A Duranti, A Tontini, G Tarzia, F Vacondio, A Fioni, A Lodola, ...
8° SAYCS, Pesaro 20-22 Ottobre 2008, P65 (Poster), 2008
2008
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