Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia JA Fraietta, SF Lacey, EJ Orlando, I Pruteanu-Malinici, M Gohil, S Lundh, ... Nature medicine 24 (5), 563-571, 2018 | 1476 | 2018 |
Histone H4 lysine 16 acetylation regulates cellular lifespan W Dang, KK Steffen, R Perry, JA Dorsey, FB Johnson, A Shilatifard, ... Nature 459 (7248), 802-807, 2009 | 739 | 2009 |
Molecular biology of aging FB Johnson, DA Sinclair, L Guarente Cell 96 (2), 291-302, 1999 | 708 | 1999 |
Astrocyte senescence as a component of Alzheimer’s disease R Bhat, EP Crowe, A Bitto, M Moh, CD Katsetos, FU Garcia, FB Johnson, ... Public Library of Science 7 (9), e45069, 2012 | 582 | 2012 |
Detection of G-quadruplex DNA in mammalian cells A Henderson, Y Wu, YC Huang, EA Chavez, J Platt, FB Johnson, ... Nucleic acids research 42 (2), 860-869, 2013 | 502 | 2013 |
Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae SG Hershman, Q Chen, JY Lee, ML Kozak, P Yue, LS Wang, FB Johnson Nucleic acids research 36 (1), 144-156, 2008 | 341 | 2008 |
The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase FB Johnson, RA Marciniak, M McVey, SA Stewart, WC Hahn, L Guarente The EMBO journal 20 (4), 905-913, 2001 | 335 | 2001 |
Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells MJ Frigault, J Lee, MC Basil, C Carpenito, S Motohashi, J Scholler, ... Cancer immunology research 3 (4), 356-367, 2015 | 331 | 2015 |
Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease R Nativio, G Donahue, A Berson, Y Lan, A Amlie-Wolf, F Tuzer, JB Toledo, ... Nature neuroscience 21 (4), 497-505, 2018 | 305 | 2018 |
Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes X Du, J Shen, N Kugan, EE Furth, DB Lombard, C Cheung, S Pak, G Luo, ... Molecular and cellular biology 24 (19), 8437-8446, 2004 | 259 | 2004 |
DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function Q Yu, YV Katlinskaya, CJ Carbone, B Zhao, KV Katlinski, H Zheng, ... Cell reports 11 (5), 785-797, 2015 | 253 | 2015 |
Nucleolar localization of the Werner syndrome protein in human cells RA Marciniak, DB Lombard, FB Johnson, L Guarente Proceedings of the National Academy of Sciences 95 (12), 6887-6892, 1998 | 246 | 1998 |
SLC25A51 is a mammalian mitochondrial NAD+ transporter TS Luongo, JM Eller, MJ Lu, M Niere, F Raith, C Perry, MR Bornstein, ... Nature 588 (7836), 174-179, 2020 | 229 | 2020 |
Sir2: an NAD-dependent histone deacetylase that connects chromatin silencing, metabolism, and aging S Imai, FB Johnson, RA Marciniak, M McVey, PU Park, L Guarente Cold Spring Harbor symposia on quantitative biology 65, 297-302, 2000 | 200 | 2000 |
Role for G-quadruplex RNA binding by Epstein-Barr virus nuclear antigen 1 in DNA replication and metaphase chromosome attachment J Norseen, FB Johnson, PM Lieberman Journal of virology 83 (20), 10336-10346, 2009 | 193 | 2009 |
Association of the Bloom syndrome protein with topoisomerase IIIα in somatic and meiotic cells FB Johnson, DB Lombard, NF Neff, MA Mastrangelo, W Dewolf, NA Ellis, ... Cancer research 60 (5), 1162-1167, 2000 | 187 | 2000 |
Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential JE Johnson, K Cao, P Ryvkin, LS Wang, FB Johnson Nucleic acids research 38 (4), 1114-1122, 2010 | 168 | 2010 |
Rudimentary G-quadruplex–based telomere capping in Saccharomyces cerevisiae JS Smith, Q Chen, LA Yatsunyk, JM Nicoludis, MS Garcia, R Kranaster, ... Nature structural & molecular biology 18 (4), 478-485, 2011 | 163 | 2011 |
Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis RJ Pignolo, RK Suda, EA McMillan, J Shen, SH Lee, Y Choi, AC Wright, ... Aging cell 7 (1), 23-31, 2008 | 163 | 2008 |
HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci KM Aird, O Iwasaki, AV Kossenkov, H Tanizawa, N Fatkhutdinov, BG Bitler, ... Journal of Cell Biology 215 (3), 325-334, 2016 | 157 | 2016 |