Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing Q Cheng*, T Wei*, L Farbiak, LT Johnson, SA Dilliard, DJ Siegwart Nature Nanotechnology 15 (4), 313-320, 2020 | 1062 | 2020 |
Size-Dependent Localization and Penetration of Ultrasmall Gold Nanoparticles in Cancer Cells, Multicellular Spheroids, and Tumors in Vivo K Huang, H Ma, J Liu, S Huo, A Kumar, T Wei, X Zhang, S Jin, Y Gan, ... ACS nano 6 (5), 4483-4493, 2012 | 865 | 2012 |
Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing T Wei*, Q Cheng*, YL Min, EN Olson, DJ Siegwart Nature Communications 11 (1), 1-12, 2020 | 410 | 2020 |
Gold nanoparticles functionalized with therapeutic and targeted peptides for cancer treatment A Kumar, H Ma, X Zhang, K Huang, S Jin, J Liu, T Wei, W Cao, G Zou, ... Biomaterials 33 (4), 1180-1189, 2012 | 376 | 2012 |
Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance T Wei, C Chen, J Liu, C Liu, P Posocco, X Liu, Q Cheng, S Huo, Z Liang, ... Proceedings of the National Academy of Sciences 112 (10), 2978-2983, 2015 | 370 | 2015 |
Superior penetration and retention behavior of 50 nm gold nanoparticles in tumors S Huo, H Ma, K Huang, J Liu, T Wei, S Jin, J Zhang, S He, XJ Liang Cancer research 73 (1), 319-330, 2013 | 332 | 2013 |
Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR–Cas gene editing S Liu, Q Cheng, T Wei, X Yu, LT Johnson, L Farbiak, DJ Siegwart Nature materials 20 (5), 701-710, 2021 | 310 | 2021 |
Multifunctional aptamer-based nanoparticles for targeted drug delivery to circumvent cancer resistance J Liu*, T Wei*, J Zhao, Y Huang, H Deng, A Kumar, C Wang, Z Liang, ... Biomaterials 91, 44-56, 2016 | 212 | 2016 |
Functionalized nanoscale micelles improve drug delivery for cancer therapy in vitro and in vivo T Wei*, J Liu*, H Ma, Q Cheng, Y Huang, J Zhao, S Huo, X Xue, Z Liang, ... Nano letters 13 (6), 2528-2534, 2013 | 184 | 2013 |
Getting drugs across biological barriers R Yang, T Wei, H Goldberg, W Wang, K Cullion, DS Kohane Advanced Materials 29 (37), 1606596, 2017 | 183 | 2017 |
Dendrimer‐based lipid nanoparticles deliver therapeutic FAH mRNA to normalize liver function and extend survival in a mouse model of hepatorenal tyrosinemia type I Q Cheng, T Wei, Y Jia, L Farbiak, K Zhou, S Zhang, Y Wei, H Zhu, ... Advanced materials 30 (52), 1805308, 2018 | 168 | 2018 |
Amphiphilic and biodegradable methoxy polyethylene glycol-block-(polycaprolactone-graft-poly (2-(dimethylamino) ethyl methacrylate)) as an effective gene carrier S Guo, Y Huang, T Wei, W Zhang, W Wang, D Lin, X Zhang, A Kumar, ... Biomaterials 32 (3), 879-889, 2011 | 119 | 2011 |
Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery X Wang, S Liu, Y Sun, X Yu, SM Lee, Q Cheng, T Wei, J Gong, ... Nature protocols 18 (1), 265-291, 2023 | 112 | 2023 |
Enhancing CRISPR/Cas gene editing through modulating cellular mechanical properties for cancer therapy D Zhang, G Wang, X Yu, T Wei, L Farbiak, LT Johnson, AM Taylor, J Xu, ... Nature nanotechnology 17 (7), 777-787, 2022 | 105 | 2022 |
The promising nanocarrier for doxorubicin and siRNA co-delivery by PDMAEMA-based amphiphilic nanomicelles Q Cheng, L Du, L Meng, S Han, T Wei, X Wang, Y Wu, X Song, J Zhou, ... ACS applied materials & interfaces 8 (7), 4347-4356, 2016 | 89 | 2016 |
Ternary complexes of amphiphilic polycaprolactone-graft-poly (N, N-dimethylaminoethyl methacrylate), DNA and polyglutamic acid-graft-poly (ethylene glycol) for gene delivery S Guo, Y Huang, W Zhang, W Wang, T Wei, D Lin, J Xing, L Deng, Q Du, ... Biomaterials 32 (18), 4283-4292, 2011 | 87 | 2011 |
Zinc oxide nanoparticles as adjuvant to facilitate doxorubicin intracellular accumulation and visualize pH-responsive release for overcoming drug resistance J Liu, X Ma, S Jin, X Xue, C Zhang, T Wei, W Guo, XJ Liang Molecular pharmaceutics 13 (5), 1723-1730, 2016 | 86 | 2016 |
Gene transfection efficacy and biocompatibility of polycation/DNA complexes coated with enzyme degradable PEGylated hyaluronic acid W Zhang, Q Cheng, S Guo, D Lin, P Huang, J Liu, T Wei, L Deng, Z Liang, ... Biomaterials 34 (27), 6495-6503, 2013 | 86 | 2013 |
Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing T Wei, Q Cheng, L Farbiak, DG Anderson, R Langer, DJ Siegwart ACS nano 14 (8), 9243-9262, 2020 | 78 | 2020 |
Dendrimeric nanosystem consistently circumvents heterogeneous drug response and resistance in pancreatic cancer J Liu, C Chen, T Wei, O Gayet, C Loncle, L Borge, N Dusetti, X Ma, ... Exploration 1 (1), 21-34, 2021 | 76 | 2021 |