| Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex W Wei, NG Ayad, Y Wan, GJ Zhang, MW Kirschner, WG Kaelin Jr Nature 428 (6979), 194-198, 2004 | 562 | 2004 |
| The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC–Cdc20 complex MS Song, SJ Song, NG Ayad, JS Chang, JH Lee, HK Hong, H Lee, ... Nature cell biology 6 (2), 129-137, 2004 | 410 | 2004 |
| Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates S Rankin, NG Ayad, MW Kirschner Molecular cell 18 (2), 185-200, 2005 | 279 | 2005 |
| Serum long noncoding RNA HOTAIR as a novel diagnostic and prognostic biomarker in glioblastoma multiforme SK Tan, C Pastori, C Penas, RJ Komotar, ME Ivan, C Wahlestedt, ... Molecular cancer 17, 1-7, 2018 | 244 | 2018 |
| The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation C Pastori, P Kapranov, C Penas, V Peschansky, CH Volmar, JN Sarkaria, ... Proceedings of the National Academy of Sciences 112 (27), 8326-8331, 2015 | 208 | 2015 |
| Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC NG Ayad, S Rankin, M Murakami, J Jebanathirajah, S Gygi, MW Kirschner Cell 113 (1), 101-113, 2003 | 207 | 2003 |
| BET bromodomain proteins are required for glioblastoma cell proliferation C Pastori, M Daniel, C Penas, CH Volmar, AL Johnstone, SP Brothers, ... Epigenetics 9 (4), 611-620, 2014 | 155 | 2014 |
| Model of Human Chorionic Gonadotropin and Lutropin Receptor Interaction That Explains Signal Transduction of the Glycoprotein Hormones (∗) WR Moyle, RK Campbell, SNV Rao, NG Ayad, MP Bernard, Y Han, ... Journal of Biological Chemistry 270 (34), 20020-20031, 1995 | 154 | 1995 |
| The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers J Long, B Li, J Rodriguez-Blanco, C Pastori, CH Volmar, C Wahlestedt, ... Journal of Biological Chemistry 289 (51), 35494-35502, 2014 | 121 | 2014 |
| Drug repositioning in glioblastoma: a pathway perspective SK Tan, A Jermakowicz, AK Mookhtiar, CB Nemeroff, SC Schürer, ... Frontiers in pharmacology 9, 218, 2018 | 96 | 2018 |
| Drug and disease signature integration identifies synergistic combinations in glioblastoma V Stathias, AM Jermakowicz, ME Maloof, M Forlin, W Walters, RK Suter, ... Nature communications 9 (1), 5315, 2018 | 95 | 2018 |
| Epigenetic pathways and glioblastoma treatment J Clarke, C Penas, C Pastori, RJ Komotar, A Bregy, AH Shah, ... Epigenetics 8 (8), 785-795, 2013 | 76 | 2013 |
| Large-scale computational screening identifies first in class multitarget inhibitor of EGFR kinase and BRD4 BK Allen, S Mehta, SWJ Ember, E Schonbrunn, N Ayad, SC Schürer Scientific reports 5 (1), 16924, 2015 | 71 | 2015 |
| Mitotic phosphorylation of rab4 prevents binding to a specific receptor on endosome membranes N Ayad, M Hull, I Mellman The EMBO journal, 1997 | 70 | 1997 |
| Redundant ubiquitin ligase activities regulate wee1 degradation and mitotic entry A Smith, S Simanski, M Fallahi, NG Ayad Cell Cycle 6 (22), 2795-2799, 2007 | 59 | 2007 |
| The APC/C ubiquitin ligase: from cell biology to tumorigenesis C Penas, V Ramachandran, NG Ayad Frontiers in oncology 1, 60, 2012 | 57 | 2012 |
| Organoid models of glioblastoma and their role in drug discovery MJ Rybin, ME Ivan, NG Ayad, Z Zeier Frontiers in cellular neuroscience 15, 605255, 2021 | 49 | 2021 |
| Casein kinase 1δ Is an APC/CCdh1 substrate that regulates cerebellar granule cell neurogenesis C Penas, EE Govek, Y Fang, V Ramachandran, M Daniel, W Wang, ... Cell reports 11 (2), 249-260, 2015 | 41 | 2015 |
| Bromodomain and extraterminal domain-containing protein inhibition attenuates acute inflammation after spinal cord injury MD Rudman, JS Choi, HE Lee, SK Tan, NG Ayad, JK Lee Experimental neurology 309, 181-192, 2018 | 40 | 2018 |
| Isolation of a preadipocyte cell line from rat bone marrow and differentiation to adipocytes O Marko, MA Cascieri, N Ayad, CD Strader, MR Candelore Endocrinology 136 (10), 4582-4588, 1995 | 39 | 1995 |
