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Christine Brown
Christine Brown
Email verificata su coh.org
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Anno
Regression of glioblastoma after chimeric antigen receptor T-cell therapy
CE Brown, D Alizadeh, R Starr, L Weng, JR Wagner, A Naranjo, ...
New England Journal of Medicine 375 (26), 2561-2569, 2016
16342016
Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma
CE Brown, B Badie, ME Barish, L Weng, JR Ostberg, WC Chang, ...
Clinical cancer research 21 (18), 4062-4072, 2015
7192015
The many HATs of transcription coactivators
CE Brown, T Lechner, LA Howe, JL Workman
Trends in biochemical sciences 25 (1), 15-19, 2000
5292000
Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit
CE Brown, LA Howe, K Sousa, SC Alley, MJ Carrozza, S Tan, ...
Science 292 (5525), 2333-2337, 2001
4402001
Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells
KS Kahlon, C Brown, LJN Cooper, A Raubitschek, SJ Forman, ...
Cancer research 64 (24), 9160-9166, 2004
4342004
T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia
A Mardiros, C Dos Santos, T McDonald, CE Brown, X Wang, LE Budde, ...
Blood, The Journal of the American Society of Hematology 122 (18), 3138-3148, 2013
4202013
Poly (A) tail length control in Saccharomyces cerevisiae occurs by message-specific deadenylation
CE Brown, AB Sachs
Molecular and cellular biology, 1998
3891998
Phase 1 studies of central memory–derived CD19 CAR T–cell therapy following autologous HSCT in patients with B-cell NHL
X Wang, LL Popplewell, JR Wagner, A Naranjo, MS Blanchard, MR Mott, ...
Blood, The Journal of the American Society of Hematology 127 (24), 2980-2990, 2016
3202016
Reporter gene imaging of targeted T cell immunotherapy in recurrent glioma
KV Keu, TH Witney, S Yaghoubi, J Rosenberg, A Kurien, R Magnusson, ...
Science translational medicine 9 (373), eaag2196, 2017
3122017
IL15 enhances CAR-T cell antitumor activity by reducing mTORC1 activity and preserving their stem cell memory phenotype
D Alizadeh, RA Wong, X Yang, D Wang, JR Pecoraro, CF Kuo, B Aguilar, ...
Cancer immunology research 7 (5), 759-772, 2019
2902019
Regional Delivery of Chimeric Antigen Receptor–Engineered T Cells Effectively Targets HER2+ Breast Cancer Metastasis to the Brain
SJ Priceman, D Tilakawardane, B Jeang, B Aguilar, JP Murad, AK Park, ...
Clinical Cancer Research 24 (1), 95-105, 2018
2632018
Neural stem cell–mediated enzyme/prodrug therapy for glioma: Preclinical studies
KS Aboody, J Najbauer, MZ Metz, M D’Apuzzo, M Gutova, AJ Annala, ...
Science translational medicine 5 (184), 184ra59-184ra59, 2013
2632013
Optimization of IL13Rα2-targeted chimeric antigen receptor T cells for improved anti-tumor efficacy against glioblastoma
CE Brown, B Aguilar, R Starr, X Yang, WC Chang, L Weng, B Chang, ...
Molecular Therapy 26 (1), 31-44, 2018
2532018
Stem-like tumor-initiating cells isolated from IL13Rα2 expressing gliomas are targeted and killed by IL13-zetakine–redirected T cells
CE Brown, R Starr, B Aguilar, AF Shami, C Martinez, M D'Apuzzo, ...
Clinical Cancer Research 18 (8), 2199-2209, 2012
2472012
PAN3 Encodes a Subunit of the Pab1p-Dependent Poly(A) Nuclease in Saccharomyces cerevisiae
CE Brown, SZ Tarun Jr, R Boeck, AB Sachs
Molecular and cellular biology 16 (10), 5744-5753, 1996
2401996
Transcription activator interactions with multiple SWI/SNF subunits
KE Neely, AH Hassan, CE Brown, LA Howe, JL Workman
Molecular and cellular biology 22 (6), 1615-1625, 2002
2272002
Chimeric antigen receptors with mutated IgG4 Fc spacer avoid fc receptor binding and improve T cell persistence and antitumor efficacy
M Jonnalagadda, A Mardiros, R Urak, X Wang, LJ Hoffman, A Bernanke, ...
Molecular Therapy 23 (4), 757-768, 2015
2162015
Targeting alpha-fetoprotein (AFP)–MHC complex with CAR T-cell therapy for liver cancer
H Liu, Y Xu, J Xiang, L Long, S Green, Z Yang, B Zimdahl, J Lu, N Cheng, ...
Clinical cancer research 23 (2), 478-488, 2017
2142017
Chimeric antigen receptors T cell therapy in solid tumor: challenges and clinical applications
HR Mirzaei, A Rodriguez, J Shepphird, CE Brown, B Badie
Frontiers in immunology 8, 327477, 2017
2082017
Tumor PD-L1 co-stimulates primary human CD8+ cytotoxic T cells modified to express a PD1: CD28 chimeric receptor
ME Prosser, CE Brown, AF Shami, SJ Forman, MC Jensen
Molecular immunology 51 (3-4), 263-272, 2012
2062012
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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