| EpCAM in carcinogenesis: the good, the bad or the ugly BTF van der Gun, LJ Melchers, MHJ Ruiters, LFMH de Leij, ... Carcinogenesis 31 (11), 1913-1921, 2010 | 320 | 2010 |
| Expression of deoxycytidine kinase in leukaemic cells compared with solid tumour cell lines, liver metastases and normal liver CL Van Der Wilt, JR Kroep, WJP Loves, MG Rots, CJ Van Groeningen, ... European Journal of Cancer 39 (5), 691-697, 2003 | 302 | 2003 |
| Epigenetic reprogramming of cancer cells via targeted DNA methylation AG Rivenbark, S Stolzenburg, AS Beltran, X Yuan, MG Rots, BD Strahl, ... Epigenetics 7 (4), 350-360, 2012 | 236 | 2012 |
| Differential effects of NF-κB and p38 MAPK inhibitors and combinations thereof on TNF-α-and IL-1β-induced proinflammatory status of endothelial cells in vitro JM Kułdo, J Westra, SA Ásgeirsdóttir, RJ Kok, K Oosterhuis, MG Rots, ... American Journal of Physiology-Cell Physiology 289 (5), C1229-C1239, 2005 | 177 | 2005 |
| Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome CM Zwaan, GJL Kaspers, R Pieters, K Hählen, GE Janka-Schaub, ... Blood, The Journal of the American Society of Hematology 99 (1), 245-251, 2002 | 169 | 2002 |
| A Novel Strategy to Modify Adenovirus Tropism and Enhance Transgene Delivery to Activated Vascular Endothelial Cells In Vitro and In Vivo K Ogawara, MG Rots, RJ Kok, HE Moorlag, AM Van Loenen, DKF Meijer, ... Human gene therapy 15 (5), 433-443, 2004 | 164 | 2004 |
| Epigenetic Editing : targeted rewriting of epigenetic marks to modulate expression of selected target genes ML de Groote, PJ Verschure, MG Rots Nucleic acids research 40 (21), 10596-10613, 2012 | 155 | 2012 |
| Role of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in methotrexate accumulation and polyglutamylation in childhood leukemia MG Rots, R Pieters, GJ Peters, P Noordhuis, CH Van Zantwijk, ... Blood, The Journal of the American Society of Hematology 93 (5), 1677-1683, 1999 | 155 | 1999 |
| Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer S Stolzenburg, MG Rots, AS Beltran, AG Rivenbark, X Yuan, H Qian, ... Nucleic acids research 40 (14), 6725-6740, 2012 | 149 | 2012 |
| Genetic evidence of assortative mating in humans MR Robinson, A Kleinman, M Graff, AAE Vinkhuyzen, D Couper, ... Nature Human Behaviour 1 (1), 1-13, 2017 | 142 | 2017 |
| Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter H Chen, HG Kazemier, ML de Groote, MHJ Ruiters, GL Xu, MG Rots Nucleic acids research 42 (3), 1563-1574, 2014 | 134 | 2014 |
| Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a–Dnmt3L single-chain fusion protein with increased DNA methylation activity AN Siddique, S Nunna, A Rajavelu, Y Zhang, RZ Jurkowska, R Reinhardt, ... Journal of molecular biology 425 (3), 479-491, 2013 | 131 | 2013 |
| Writing of H3K4Me3 overcomes epigenetic silencing in a sustained but context-dependent manner D Cano-Rodriguez, RAF Gjaltema, LJ Jilderda, P Jellema, ... Nature communications 7 (1), 1-11, 2016 | 130 | 2016 |
| Therapeutic modulation of endogenous gene function by agents with designed DNA‐sequence specificities TG Uil, HJ Haisma, MG Rots Nucleic acids research 31 (21), 6064-6078, 2003 | 114 | 2003 |
| mRNA expression levels of methotrexate resistance-related proteins in childhood leukemia as determined by a standardized competitive template-based RT-PCR method MG Rots, JC Willey, G Jansen, CH Van Zantwijk, P Noordhuis, JP DeMuth, ... Leukemia 14 (12), 2166-2175, 2000 | 102 | 2000 |
| Protein transduction domains and their utility in gene therapy AMJ Beerens, AFY Al Hadithy, MG Rots, HJ Haisma Current gene therapy 3 (5), 486-494, 2003 | 84 | 2003 |
| A novel ex vivo model system for evaluation of conditionally replicative adenoviruses therapeutic efficacy and toxicity TO Kirby, A Rivera, D Rein, M Wang, I Ulasov, M Breidenbach, M Kataram, ... Clinical Cancer Research 10 (24), 8697-8703, 2004 | 83 | 2004 |
| Genome analyses of> 200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders S Ligthart, A Vaez, U Võsa, MG Stathopoulou, PS De Vries, BP Prins, ... The American Journal of Human Genetics 103 (5), 691-706, 2018 | 81 | 2018 |
| Polyinosinic acid enhances delivery of adenovirus vectors in vivo by preventing sequestration in liver macrophages HJ Haisma, JAAM Kamps, GK Kamps, JA Plantinga, MG Rots, AR Bellu Journal of general virology 89 (5), 1097-1105, 2008 | 80 | 2008 |
| Engineering zinc finger protein transcription factors: the therapeutic relevance of switching endogenous gene expression on or off at command WM Gommans, HJ Haisma, MG Rots Journal of molecular biology 354 (3), 507-519, 2005 | 79 | 2005 |
