| PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4+ T cell function MA Ghonim, K Pyakurel, SV Ibba, AA Al-Khami, J Wang, P Rodriguez, ... Journal of Translational Medicine 13, 1-12, 2015 | 49 | 2015 |
| PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice MA Ghonim, K Pyakurel, SV Ibba, J Wang, P Rodriguez, AA Al-Khami, ... Clinical Science 129 (11), 951-962, 2015 | 39 | 2015 |
| Fuelling the mechanisms of asthma: Increased fatty acid oxidation in inflammatory immune cells may represent a novel therapeutic target AA Al‐Khami, MA Ghonim, L Del Valle, SV Ibba, L Zheng, K Pyakurel, ... Clinical & Experimental Allergy 47 (9), 1170-1184, 2017 | 37 | 2017 |
| DNA-dependent protein kinase inhibition blocks asthma in mice and modulates human endothelial and CD4+ T-cell function without causing severe combined immunodeficiency MA Ghonim, K Pyakurel, J Ju, PC Rodriguez, MR Lammi, C Davis, ... Journal of Allergy and Clinical Immunology 135 (2), 425-440, 2015 | 32 | 2015 |
| Minocycline blocks asthma-associated inflammation in part by interfering with the T cell receptor-nuclear factor κB-GATA-3-IL-4 axis without a prominent effect on poly (ADP … AS Naura, H Kim, J Ju, PC Rodriguez, J Jordan, AD Catling, BM Rezk, ... Journal of Biological Chemistry 288 (3), 1458-1468, 2013 | 27 | 2013 |
| Microparticles in systemic sclerosis: potential pro‐inflammatory mediators and pulmonary hypertension biomarkers MR Lammi, LA Saketkoo, SC Okpechi, MA Ghonim, D Wyczechowska, ... Respirology 24 (7), 675-683, 2019 | 21 | 2019 |
| Sulfated non-anticoagulant heparin blocks Th2-induced asthma by modulating the IL-4/signal transducer and activator of transcription 6/Janus kinase 1 pathway MA Ghonim, J Wang, SV Ibba, HH Luu, K Pyakurel, I Benslimane, ... Journal of Translational Medicine 16, 1-12, 2018 | 19 | 2018 |
| Potential of inducible nitric oxide synthase as a therapeutic target for allergen-induced airway hyperresponsiveness: a critical connection to nitric oxide levels and PARP activity SV Ibba, MA Ghonim, K Pyakurel, MR Lammi, A Mishra, AH Boulares Mediators of inflammation 2016, 2016 | 12 | 2016 |
| Treatment with intranasal iloprost reduces disease manifestations in a murine model of previously established COPD MR Lammi, MA Ghonim, K Pyakurel, AS Naura, SV Ibba, CJ Davis, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 310 (7 …, 2016 | 8 | 2016 |
| Acute effect of inhaled iloprost on exercise dynamic hyperinflation in COPD patients: A randomized crossover study MR Lammi, MA Ghonim, J Johnson, J D'Aquin, JB Zamjahn, A Pellett, ... Respiratory medicine 180, 106354, 2021 | 2 | 2021 |
| The catalytic subunit of DNA-PK has a unique function in inflammation independently of Ku70 and DNA repair: a new opportunity to target the enzyme without interfering with DNA … MA Ghonim, K Pyakurel, H Luu, S Okpechi, J Ju, H Boulares The Journal of Immunology 200 (1_Supplement), 173.18-173.18, 2018 | 2 | 2018 |
| Poly (ADP) Ribose Polymerase (PARP)‐1 Is A critical Determinant of Atopic Dermatitis through Control of Allergen‐Induced Th2 And T‐regulatory Responses And Expression of The … MA Ghonim, MM Abouzeid, K Pyakurel, J Wang, A Tarhuni, H Boulares The FASEB Journal 31, 995.13-995.13, 2017 | 2 | 2017 |
| THE DUAL ACTIONS OF DNA REPAIR ENZYME, PARP‐1, IN COLON INFLAMMATION AND CARCINOGENESIS AF Tarhuni, Y Errami, AH El‐Bahrawy, A Al‐Khami, M Gohnim, A Naura, ... The FASEB Journal 30, 1268.3-1268.3, 2016 | 1 | 2016 |
| Common and differential roles of inducible NO synthase and poly (ADP-ribose) polymerase in allergen-induced inflammation and airway hyperresponsiveness: a potential connection … SV Ibba Università degli Studi di Milano, 2015 | 1 | 2015 |
| Acute effects on inhaled iloprost on dynamic hyperinflation and exercise performance in COPD patients, independent of pulmonary hypertension MR Lammi, B Aiello, J Johnson, M Ghonim, K Pyakurel, J D'Aquin, ... B95. GETTING BETTER: ADVANCES IN COPD THERAPIES, A3640-A3640, 2015 | 1 | 2015 |
| DNA‐PK Is Activated in Human Atherosclerotic Plaques And Its Partial Inhibition by Gene Heterozygosity Reduces Atherogenesis in Mouse Model of The Disease MA Ghonim, K Pyakurel, H Luu, M Dean, H Bazan, H Boulares The FASEB Journal 32, 570.2-570.2, 2018 | | 2018 |
| Poly (ADP‐ribosyl) ation of Signal Transducer And Activator of Transcription (STAT) 6 by Poly (ADP‐ribose) Polymerase (PARP)‐1 Is Critical for Its Integrity And Subsequent … J Wang, M Ghonim, SV Ibba, K Pyakurel, M Lammi, H Boulares The FASEB Journal 31, 820.7-820.7, 2017 | | 2017 |
| Microparticles From Systemic Sclerosis Patients May Affect Vascular Inflammation of Endothelial Cells In Vitro MR Lammi, S Okpechi, D Wyczechowska, LA Saketkoo, N Bauer, ... Circulation 134 (suppl_1), A20249-A20249, 2016 | | 2016 |
| Endothelial Microparticles As Biomarkers Of Pulmonary Hypertension In Systemic Sclerosis MR Lammi, LA Saketkoo, S Okpechi, D Wyczechowska, N Bauer, ... D54. CLINICAL PULMONARY HYPERTENSION, A7390-A7390, 2016 | | 2016 |
| DNA‐Dependent Protein Kinase Inhibition Prevents Manifestation of Acute Lung Injury in Mice, a Novel Target Associated with Th1 Type Disease K Pyakurel, M Ghonim, S Ibba, A Tarhuni, J Wang, H Boulares The FASEB Journal 30, 1202.4-1202.4, 2016 | | 2016 |
