| Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors AS Kalgutkar, AB Marnett, BC Crews, RP Remmel, LJ Marnett Journal of medicinal chemistry 43 (15), 2860-2870, 2000 | 462 | 2000 |
| Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors AS Kalgutkar, BC Crews, SW Rowlinson, AB Marnett, KR Kozak, ... Proceedings of the National Academy of Sciences 97 (2), 925-930, 2000 | 344 | 2000 |
| Lamotrigine clearance during pregnancy TA Tran, IE Leppik, K Blesi, ST Sathanandan, R Remmel Neurology 59 (2), 251-255, 2002 | 315 | 2002 |
| Primary hepatocytes outperform Hep G2 cells as the source of biotransformation functions in a bioartificial liver. SL Nyberg, RP Remmel, HJ Mann, MV Peshwa, WS Hu, FB Cerra Annals of surgery 220 (1), 59, 1994 | 293 | 1994 |
| Concise review of the cytochrome P 450 s and their roles in toxicology CJ Omiecinski, RP Remmel, VP Hosagrahara Toxicological Sciences 48 (2), 151-156, 1999 | 225 | 1999 |
| Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer S Nagar, RP Remmel Oncogene 25 (11), 1659-1672, 2006 | 221 | 2006 |
| Rat hepatocyte spheroids formed by rocked technique maintain differentiated hepatocyte gene expression and function CM Brophy, JL Luebke‐Wheeler, BP Amiot, H Khan, RP Remmel, ... Hepatology 49 (2), 578-586, 2009 | 181 | 2009 |
| Zidovudine triphosphate and lamivudine triphosphate concentration–response relationships in HIV-infected persons CV Fletcher, SP Kawle, TN Kakuda, PL Anderson, D Weller, LR Bushman, ... Aids 14 (14), 2137-2144, 2000 | 165 | 2000 |
| Rapid, large‐scale formation of porcine hepatocyte spheroids in a novel spheroid reservoir bioartificial liver SL Nyberg, J Hardin, B Amiot, UA Argikar, RP Remmel, P Rinaldo Liver transplantation 11 (8), 901-910, 2005 | 162 | 2005 |
| Effect of aging on glucuronidation of valproic acid in human liver microsomes and the role of UDP-glucuronosyltransferase UGT1A4, UGT1A8, and UGT1A10 UA Argikar, RP Remmel Drug Metabolism and Disposition 37 (1), 229-236, 2009 | 160 | 2009 |
| Human bilirubin UDP-glucuronosyltransferase catalyzes the glucuronidation of ethinylestradiol T Ebner, RP Remmel, B Burchell MOLECULAR PHARMACOLOGY-NEW YORK THEN BALTIMORE- 43, 649-649, 1993 | 159 | 1993 |
| Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus S Chen, D Beaton, N Nguyen, K Senekeo-Effenberger, ... Journal of Biological Chemistry 280 (45), 37547-37557, 2005 | 158 | 2005 |
| Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2, 3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through … K Senekeo-Effenberger, S Chen, E Brace-Sinnokrak, JA Bonzo, MF Yueh, ... Drug metabolism and disposition 35 (3), 419-427, 2007 | 147 | 2007 |
| Genomewide association study of tacrolimus concentrations in African American kidney transplant recipients identifies multiple CYP3A5 alleles WS Oetting, DP Schladt, W Guan, MB Miller, RP Remmel, C Dorr, ... American Journal of Transplantation 16 (2), 574-582, 2016 | 128 | 2016 |
| High-speed simultaneous determination of nine antiepileptic drugs using liquid chromatography-mass spectrometry M Subramanian, AK Birnbaum, RP Remmel Therapeutic drug monitoring 30 (3), 347-356, 2008 | 127 | 2008 |
| Acridine-based agents with topoisomerase II activity inhibit pancreatic cancer cell proliferation and induce apoptosis JR Goodell, AV Ougolkov, H Hiasa, H Kaur, R Remmel, DD Billadeau, ... Journal of medicinal chemistry 51 (2), 179-182, 2008 | 127 | 2008 |
| Association of carbamazepine major metabolism and transport pathway gene polymorphisms and pharmacokinetics in patients with epilepsy YG Puranik, AK Birnbaum, SE Marino, G Ahmed, JC Cloyd, RP Remmel, ... Pharmacogenomics 14 (1), 35-45, 2013 | 126 | 2013 |
| Probing the mechanism of action and decomposition of amino acid phosphomonoester amidates of antiviral nucleoside prodrugs EJ McIntee, RP Remmel, RF Schinazi, TW Abraham, CR Wagner Journal of medicinal chemistry 40 (21), 3323-3331, 1997 | 118 | 1997 |
| Extended liver-specific functions of porcine hepatocyte spheroids entrapped in collagen gel A Lazar, HJ Mann, RP Remmel, RA Shatford, FB Cerra, WS Hu In Vitro Cellular & Developmental Biology-Animal 31, 340-346, 1995 | 118 | 1995 |
| Food effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy AK Birnbaum, A Karanam, SE Marino, CM Barkley, RP Remmel, ... Epilepsia 60 (8), 1586-1592, 2019 | 116 | 2019 |
William S. OettingProfessor, University of MinnesotaVerified email at umn.edu
